High-grade transformation in adenoid cystic carcinoma: Can it be diagnosed on cytology? A cytohistological correlation
CYTOJOURNAL(2024)
摘要
Adenoid cystic carcinomas (ADCC) are distinctive salivary gland neoplasms with characteristic histomorphology. The diagnosis of dedifferentiation/high-grade transformation (HGT) indicates poor prognosis and is most often made on histopathology. We present a case of ADCC arising from a minor salivary gland tumor exhibiting HGT, reaching up to the submandibular gland and having lymph node metastases, suspected on fine-needle aspiration cytology. The index case highlights the awareness of the entity of the HGT of salivary gland tumors and raises suspicion for cytological diagnosis.
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关键词
Adenoid cystic carcinoma,High-grade transformation,Cytopathology,Histopathology,Dedifferentiation
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