N-Arylamino-1,2,4-oxadiazol-5(4H)-ones: Synthesis, Luminescent, Antibacterial, and Antienteroviral Properties

Method for the preparation of N-arylamino-1,2,4-oxadiazol-5(4H)-ones via reduction of N-nitrophenyl-1,2,4-oxadiazol-5(4H)-ones with tin(II) chloride has been developed. The results of experiments to study photophysical properties showed that the synthesized compounds have potential for use as fluorophores in the visible region of the spectrum. In addition, one of the obtained N-arylamino-1,2,4-oxadiazol-5(4H)-ones demonstrate antibacterial activity against both Gram-positive (S. Aureus) and Gram-negative (E. Coli) strains.