The importance of ABO in platelet refractoriness, an often overlooked option

ABO-non-identical (ni) platelets provide less of an increase in platelet count and may increase the length of patient transfusions. The paper by Han and Badami showed that ABO-ni platelets may be a risk factor for immune platelet transfusion refractoriness. Commentary on: Han et al. ABO non-identical platelet transfusions, immune platelet refractoriness and platelet support. Br J Haematol 2024 (Online ahead of print). doi: 10.1111/bjh.19359.