A comprehensive review on transdermal patches as an efficient approach for the delivery of drug

POLYMER-PLASTICS TECHNOLOGY AND MATERIALS(2024)

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摘要
In past years, various studies have considered transdermal drug delivery system for improving patient compliance. One approach to deliver drug via transdermal route is transdermal patch. These patches include single-layer drug in adhesive patches and micro reservoir transdermal patch & matrix system. Acrylic-acid, hydroxypropyl methylcellulose (HPMC) and polyethylene glycol are commonly used polymers for manufacturing of transdermal patches. Characterization of patches includes patch thickness, weight uniformity, irritation studies, in-vitro drug release and permeation studies. This review summarizes various polymers, types of transdermal patches and evaluation of transdermal patches based on up-to-date data extracted from reputed journals and official websites.
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关键词
Characterization,drug hydrolysis,skin irritation study,transdermal drug delivery system,transdermal patch
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