A Review on Advancement of Cancer Therapy with Metal Based Nanoparticle

Muhammad Irfan, Affifa Tajammal, Ansa Gulnaz, Mehtab Shareef

Lahore Garrison University Journal of Life Sciences(2024)

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摘要
The primary cause of numerous diseases that frequently affect the human body is a compromised immune system. For instance, it can increase the body's susceptibility to infection, which also increases the body's resistance to medicines, by triggering pro-inflammatory reactions and even the loss of good cells and tissues. Metal nanoparticles have the potential to overcome the challenges caused by conventional chemotherapies. Metal nanoparticles play an essential role in the treatment of cancer by targeting, gene suppression, and drug delivery to thetargeted area. The best suitable metal nanoparticles better work with targeted ligands to control the energy deposition within the tumors. Other than therapeutic advantages, metal nanoparticles are also helpful as a diagnostic tool for the imaging of cancerous cells. Moreover, metal nanoparticles provide beneficial options in controlled targeted drug delivery, instant diagnosis, and therapeutic methods. Nanoparticles are useful as therapies and diagnostics because cancer cells are heterogeneous. Breast cancer anti-cancer therapy is difficult due to the disease's aggressive spread to the body. Noble metal nanoparticles are used in the treatment of cancer because of their distinctive features, great biocompatibility, surface effects, and tiny size effects. Numerous cancer treatments have been developed thanks to advances in science and technology, but the global mortality rate for cancer patients is still astronomically high, necessitating conventional treatment approaches in order to preserve lives. Scientists are trying to find a cancer cure, working day and night. Due to their effectiveness and promising outcomes, nanoparticles for the treatment of cancer have acquired relevance.
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