SinoNasal Microbiota Transfer to treat recalcitrant chronic rhinosinusitis: A case series

Sandeep K. Gill, Juan C. Hernaiz-Leonardo,Thaddeus J. Edens, Athenea Pascual, Chris Tang,Judy Fan,Andrew Thamboo,Warren Mullings,Saad Alsaleh,Bader M. Alim,Amin R. Javer,Amee R. Manges

INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY（2024）

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摘要

Key Points SinoNasal Microbiota Transfer (SNMT) was safe with immediate benefit in all recipients, with sustained improvement in two of three recipients for up to 180 days. The addition of antimicrobial photodynamic therapy worsened chronic rhinosinusitis. These promising SNMT results warrant further study of safety and efficacy.

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关键词

chronic rhinosinusitis,experimental therapy,microbiome,microbiome therapy,mucus transplant,sinusitis

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