A comprehensive review of m⁶A research in cervical cancer

Cervical cancer (CC) remains one of the most common malignancies among women worldwide, posing a serious threat to women's health. N6-methyladenosine (m(6)A) modification, as the most abundant type of RNA methylation modification, and has been found to play a crucial role in various cancers. Current research suggests a close association between RNA m(6)A modification and the occurrence and progression of CC, encompassing disruptions in m(6)A levels and its regulatory machinery. This review summarizes the current status of m(6)A modification research in CC, explores the mechanisms underlying m(6)A levels and regulators (methyltransferases, demethylases, reader proteins) in CC and examines the application of small-molecule inhibitors of m(6)A regulators in disease treatment. The findings provide new insights into the future treatment of CC.