Figure S3 from <i>De Novo</i> Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression

Naveen Kumar Tangudu,Raquel Buj, Hui Wang,Jiefei Wang, Aidan R. Cole,Apoorva Uboveja, Richard Fang, Amandine Amalric, Baixue Yang,Adam Chatoff, Claudia V. Crispim,Peter Sajjakulnukit,Maureen A. Lyons,Kristine Cooper,Nadine Hempel,Costas A. Lyssiotis,Uma R. Chandran,Nathaniel W. Snyder,Katherine M. Aird

crossref（2024）

引用 0|浏览3

暂无评分

摘要

Anti-folates induce death and increased DNA damage foci in shCdkn2a cells; shp16 cells do not mount a robust senescence-associated secretory phenotype (SASP) in response to Palbociclib; anti-proliferative effects of anti-folates are longer-lived than palbociclib; and folate transporters are upregulated in shp16/shCdk2na cells. Related to Figure 4.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要

Figure S3 from &lt;i&gt;De Novo&lt;/i&gt; Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression

Figure S3 from <i>De Novo</i> Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression