Cabotegravir and Rilpivirine Long Acting Injectables in a Pregnant Woman Living with HIV

Lena van der Wekken-Pas,Fabian Weiss, Charlotte Simon-Zuber, Rena Sebisch,Carmen Wiese,Elisabeth van Leeuwen,David Burger,Angela Colbers

Clinical infectious diseases/Clinical infectious diseases (Online University of Chicago Press)（2024）

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摘要

This case report describes bimonthly LAI CAB/RPV prior to and throughout pregnancy. CAB concentration was comparable to non-pregnant individuals, RPV was 70-75% lower. No virologic failure orvertical transmission occurred. Despite placental transfer, no congenital malformations were noted. Bimonthly CAB/RPV LAI may not be suitable for pregnant women and monitoring of exposed infants is warranted.

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