Catalytic oxidative cyclization of α-carbonyl-γ-alkynyl sulfoxonium ylides for stereospecific synthesis of (1Z,3Z)-1,3-bismethyleneisobenzofurans

A new copper(II)-catalyzed annulation-enabled radical cross-coupling cascade of α-carbonyl-γ-alkynyl sulfoxonium ylides with sulfonyl hydrazides in the presence of tert-butyl hydroperoxide (TBHP) is reported, enabling a completely regio- and stereoselective strategy...