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Outcomes and Prognosis of Postpartum Hemorrhage According to Management Protocol: an 11-Year Retrospective Study from Two Referral Centers

Ye Won Jung, Jin Kim,Won Kyo Shin,Soo Youn Song, Jae Sung Choi, Suk Hwan Hyun, Young Bok Ko, Mina Lee, Byung Hun Kang, Bo Young Kim,Jin Hong Min,Yong Nam In,Sang Min Jung,Se Kwang Oh,Heon Jong Yoo

WORLD JOURNAL OF EMERGENCY SURGERY(2024)

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摘要
No standard treatment guidelines have been established for postpartum hemorrhage (PPH). We aimed to assess the differences in outcomes and prognoses between patients with PPH who underwent surgical and non-surgical treatment. This retrospective study included 230 patients diagnosed with PPH at two referral hospitals between August 2013 and October 2023. The patients were divided into non-surgical (group 1, n = 159) and surgical intervention groups (group 2, n = 71). A subgroup analysis was performed by dividing the surgical intervention group into immediate (n = 45) and delayed surgical intervention groups (n = 26). Initial lactic acid levels and shock index were significantly higher in group 2 (2.85 ± 1.37 vs. 4.54 ± 3.63 mmol/L, p = 0.001, and 0.83 ± 0.26 vs. 1.10 ± 0.51, p < 0.001, respectively). Conversely, initial heart rate and body temperature were significantly lower in group 2 (92.5 ± 21.0 vs. 109.0 ± 28.1 beat/min, p < 0.001, and 37.3 ± 0.8 °C vs. 37.0 ± 0.9 °C, p = 0.011, respectively). Logistic regression analysis identified low initial body temperature, high lactic acid level, and shock index as independent predictors of surgical intervention (p = 0.029, p = 0.027, and p = 0.049, respectively). Regarding the causes of PPH, tone was significantly more prevalent in group 1 (57.2
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关键词
Postpartum Hemorrhage,Lactic acid,Hemorrhagic shock,Uterine Atony,Hysterectomy,Disseminated intravascular coagulation,Uterine artery embolization
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