Intracranial CAR-T Cell Delivery in Glioblastoma Patients
Trends in cancer(2024)
摘要
Chimeric antigen receptor (CAR)-T cell therapy is emerging as a promising approach for improving outcomes in high-grade glioma. Here, we highlight three recent studies that reported safety and feasibility of intracranial CAR-T cell administration in patients with glioblastoma (GBM) as well as preliminary evidence of potential responses, supporting further investigations of this approach.
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关键词
glioblastoma,CAR-T cells,clinical trial,immunotherapy
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