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Design, Synthesis, and Biological Evaluation of Novel 1-Amido-2-one-4-thio-deoxypyranose As Potential Antitumor Agents for Multiple Myeloma

Xiaomei Li, Hui Zhang,Sanfeng Dong,Xuejie Gao,Haiguo Sun, Zhaoyin Zhou,Ke Hu,Shushan Guo,Qikai Zhang, Zhufeng Guo, Samuel Jacob Bunu,Jianming Zhu,Bo Li,Yong Zhang,Jingshan Shen,Haji Akber Aisa,Zhijian Xu,Haiyan Cai,Jumei Shi,Weiliang Zhu

BIOORGANIC & MEDICINAL CHEMISTRY（2024）

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Key words
Multiple myeloma,1-amido-2-one-4-thio-deoxypyranose,TRIP13 inhibitor,In vivo activity
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