基本信息
浏览量:26
职业迁徙
个人简介
Anne-Sophie did her PhD in Paris, France, at Pierre and Marie Curie University in Prof. David Klatzmann lab. She showed that a subpopulation of regulatory T cells (Tregs) was constantly activated by self-antigens and recognized self-tumor antigens when a tumor was present, leading to their rapid reactivation, the suppression of the conversion of naïve T cells to effector T cells, and the protection of the tumor cells.
She then moved to Brisbane, Australia, where she undertook her first postdoc under the supervision of Prof. Ian Frazer, who is internationally renowned for the co-creation of the technology for the cervical cancer vaccines Gardasil and Cervarix. She carried out a highly successful and independent program of work on regulatory mast cells inducing tolerance to papillomavirus-associated cancerous lesions in mice.
She then joined Prof Ranjeny Thomas, recently awarded member of the Order of Australia, to work on the immunotherapy of autoimmune diseases such as T1D and SpA. In T1D her pre-clinical data showed that antigen-specific liposome-based immunotherapy promoted Treg protection of hyperglycemic NOD mice through bystander suppression of third-party CD8 T cells. In SpA, she is focusing on the interaction between the gut microbiome, the immune system, and the development of arthritic inflammation.
研究兴趣
论文共 42 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Anne-Sophie Bergot, Benjamin Cai,Rabina Giri,Miss Amy Cameron,Emily Duggan, Kai Lim,Linda Rehaume,Mark Morrison,Jakob Begun,Ranjeny Thomas
INTERNAL MEDICINE JOURNAL (2023): 57-57
引用0浏览0引用
0
0
Annals of the Rheumatic Diseasesno. Suppl 1 (2023): 471.2-472
Immunology & Cell Biologyno. 1 (2022): 36-48
Clinical immunology (Orlando, Fla.) (2022): 109220-109220
biorxiv(2022)
Aditi Narsale,Breanna Lam,Rosita Moya,TingTing Lu,Alessandra Mandelli, Irene Gotuzzo, Benedetta Pessina,Gian Maria Giamporcaro,Rhonda Geoffrey,Kerry Buchanan,Mark Harris,Anne-Sophie Bergot,
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn