The purpose of this study is to objectively quantify physical activity and sedentary behaviour in children and adolescents during hospital admission using device-based monitoring and investigate the association between sedentary behaviour and pain, constipation, surgery status, movement restrictions, 30-day readmission, and length of stay. Children and adolescents aged 2 ≤ 17 years admitted between March and September 2025 to three paediatric departments at a Danish hospital were eligible for this prospective observational study. Children and adolescents scheduled for day surgery and wheelchair users were excluded. All participants wore two triaxial accelerometers throughout their hospital stay. In total, 103 hospitalised children and adolescents were included. The participants spent 45 min per day (interquartile range 20–125) in upright position (standing and walking time combined) and were sedentary (sitting and lying time combined) for 23.3 h per day (21.8–23.7). Adolescents undergoing spine surgery were sedentary for 23.6 h per day (23.5–23.7), of which 22.6 h (21.8–23.0) were spent lying in bed. Sedentary behaviour was significantly associated with higher age (p < 0.001), opioid consumption beyond standardised analgesia (p = 0.028), and orthopaedic procedures (p < 0.001). No associations between sedentary behaviour and length of stay (p = 0.391), 30-day readmission (p = 0.467), laxative use (p = 0.695), and postoperative movement restrictions (p = 0.637) were found. Conclusion: Hospitalised children and adolescents in this study exhibited high levels of sedentary behaviour. The findings highlight that mobilisation strategies are needed across all paediatric surgical procedures, but adolescents, patients undergoing orthopaedic or spine procedures, and those prescribed opioids beyond standardised analgesia require particular attention. There is a need for further evidence of the consequences of sedentary behaviour during hospitalisation among children and adolescents.
To assess temporal changes in the timing of pulmonary valve replacement (PVR) among patients with tetralogy of Fallot and to determine whether temporal shifts toward earlier PVR were accompanied by differences in ventricular volumes, ventricular function and exercise capacity after PVR. The timing of PVR was evaluated in a national, retrospective cohort using the Aalen-Johansen method to estimate cumulative incidence while accounting for death as competing risk. Trends in ventricular volumes, ventricular function and exercise capacity were assessed in patients with prior PVR, who underwent cardiac imaging and exercise testing in a cross-sectional study using robust linear regression. Among 463 potential candidates for PVR in the retrospective cohort, estimated time from repair to PVR was 34 years, 22 years and 16 years in patients born in 1940–1976, 1977–1999, and 2000–2021, respectively (p < 0.001). In total, 153 patients with prior PVR born between 1942 and 2009 were examined in the cross-sectional study. Estimated right ventricular end-systolic volume index was lower by 5.43 mL/m2 per decade (p = 0.02), estimated right ventricular ejection fraction increased by 2.08 Overview of temporal changes in the timing of pulmonary valve replacement and impact on outcomes. The median time from repair to pulmonary valve replacement for each birth era was based on a nationwide cohort of patients with tetralogy of Fallot and estimated using the cumulative incidence function. The temporal trends in ventricular volumes, ventricular function and exercise capacity were estimated based on the results from patients who underwent cardiac magnetic resonance imaging, transthoracic echocardiography and cardiopulmonary exercise testing as part of a national multicentre cross-sectional study and estimated using robust regression methods
To assess the long-term economic and welfare burden of Ménière’s disease, focusing on healthcare costs, income, and reliance on social benefits before and after the first hospital-recorded diagnosis. We conducted a nationwide matched cohort study in Denmark, involving 5,434 patients with a hospital-recorded Ménière’s disease diagnosis later confirmed by an otorhinolaryngologist and 16,302 matched controls based on age, sex, civil status, municipality, and index year defined by the first hospital registration of Ménière’s disease. The mean age was 59 years, and 56
To investigate the association between multimorbidity level, all-cause 30-day readmissions, and 30-day mortality in a cohort of patients hospitalised with an ambulatory care sensitive condition. Older patients with moderate or severe multimorbidity had higher 30-day readmission and mortality compared with those without multimorbidity, increasing with the level of multimorbidity. Multimorbidity increases 30-day readmission and mortality risk. Identifying high-risk patients and tailoring care during and after hospitalisation is therefore crucial. We investigated the association between multimorbidity level, all-cause 30-day readmissions, and post-discharge 30-day mortality. Using Danish national registries, we identified patients aged ≥ 65 years hospitalized for ambulatory care-sensitive conditions between 2013–2018. Multimorbidity was defined as having 2–3 (moderate) or ≥ 4 (severe) of 39 chronic conditions. We estimated 30-day cumulative incidence of readmission after discharge and used Cox regression to calculate hazard ratios (HRs) for readmission and mortality. Among 178,445 patients, median age was 78 years (IQR: 71–85), 59
PURPOSE:Musculoskeletal disorders (MSDs) are a leading cause of sickness absence from work and early retirement. While structured workplace dialogues about musculoskeletal pain are recommended, their implementation remains challenging. This study explored the implementation of the 'Talk About Pain-Take Action Together'' toolbox in two Danish public workplaces. METHODS:Qualitative observational implementation study informed by reflexive thematic analysis was conducted. Two workplaces with physically demanding roles were included: one with researcher-initiated implementation during the study period and one with internally initiated implementation prior to the study. Data were collected through observations, memos, emails, and four focus group interviews with 10 participants including employees, managers, and occupational safety and health consultants. RESULTS:Workplace 1 (WP1) implemented the toolbox, employing seven strategies: identifying and preparing champions, conducting a local needs assessment, distributing educational materials, reminding clinicians, tailoring strategies, organising implementation team meetings, and creating learning collaboratives. Key enablers included management engagement, ongoing exposure, and creating a safe environment, whereas lack of time was identified as a barrier. At workplace 2 (WP2), three strategies were employed: identifying and preparing champions, distributing educational materials, and conducting educational meetings. However, the toolbox was never fully implemented, hindered by time-related barriers, organisational restructuring, and unclear roles and responsibilities. CONCLUSIONS:Effective implementation of workplace MSD interventions requires management engagement, time allocation, and clear roles.
