福山大学

Wavefront Coding is a powerful technology for extending depth of field, but it has the problem of generating artifacts such as ringing in reconstructed images. As countermeasures, the application of apodization and optimization using deep learning have been proposed. In this paper, we modified the apodization conditions of the intermediate images and reconstruction filters to generate the reconstructed images. We then reduced artifacts in the reconstructed images using deep learning with a high-resolution dataset, resulting in improved spatial frequency characteristics in 4K-equivalent high-resolution images.

The efficacy of immune checkpoint inhibitors (ICIs) in colon cancer (CC) is limited by the tolerogenic immune landscape of both the tumor and the intestine. Here, we investigated the impact of microbial metabolic pathways associated with ICI responsiveness on anti-tumor immunity in CC. Sulfur amino acid (Saa) metabolic pathways were enriched in ICI responders and in individuals without CC. In murine models, high-Saa diets restricted CC progression, increased colonic mucus thickness, and promoted the expansion of mucus-dwelling Mucispirillum schaedleri (M. schaedleri). Dietary Saa supplementation increased the frequency of activated intratumoral cytotoxic CD8+ T cells. The protective effect of high-Saa diets required type 1 conventional dendritic cells (cDC1s) in tumor-draining lymph nodes, where M. schaedleri was sufficient to drive cDC1 expansion and activation. Mechanistically, M. schaedleri stimulated natural killer T (NKT) cell expansion and secretion of the chemokine XCL1, which was essential for cDC1 recruitment and anti-tumor immunity. Dietary modulation of this NKT-XCL1-cDC1 axis in combination with ICIs may open avenues for improved treatments of CC.

We investigate the use of half-precision floating-point numbers (FP16) in mixed-precision linear solvers for lattice QCD simulations. Since the emergence of GPUs for general-purpose, mixed-precision algorithms that combine single-precision (FP32) with double-precision (FP64) arithmetics have become widely used in this field and others. While FP32-based methods are now well established, we examine the practicality of using FP16. In this work, we introduce rescaling steps in both the outer iterative refinement step and the inner BiCGStab solver to avoid numerical instability. In our experiments with a simple Wilson kernel, the solver shows improved stability, and the additional iteration count compared to the FP64 version remains within 20\%, indicating that the FP16 version is practical for use. We believe that the proposed rescaling methods can also benefit other mixed precision preconditioners in avoiding underflows.

The rapid advancement of high-speed and high-power wide-bandgap (WBG) semiconductor devices such as SiC is expected to expand the operating power range of power electronics systems including inverters. However, electromagnetic interference (EMI) caused by the switching operations of power semiconductor devices increases accordingly. The authors have been developing a real-time gate control circuit to suppress the over-shoot generated during the switching transitions of these next-generation semiconductor switches. In this paper, a novel cur-rent overshoot detection circuit with a simple configuration is proposed. The detection theory of the newly designed circuit is described when it is applied to an inverter IGBT. Furthermore, the operational evaluation results of the detection circuit proto-typed using a commercially available MOSFET for fundamental validation are presented.

This study examined the relationship between traditional male-role beliefs and negative social reactions toward male victims of sexual violence in Japan. While previous research has focused on Western contexts, this study explored how such beliefs shape the perceptions of male victims in a non-Western cultural setting. A vignette-based survey was conducted with 291 Japanese participants (154 women, 137 men, Mage = 54.02, SDage = 17.56), selected after exclusions, with gender and age quotas matched to national census data. Participants completed validated measures, including the Traditional Male Role Scale and the Negative Social Reactions Scale, to assess their adherence to traditional male roles and responses to male victims of sexual assault. The results revealed that traditional male-role beliefs were associated with negative social reactions, including stigma, victim blaming, and egocentric or intrusive responses. The belief in male superiority over women, particularly in sexual contexts, showed the strongest relationship with these reactions (take control: β = 0.42; victim blame: β = 0.32; egocentric: β = 0.35; intrusiveness: β = 0.41). Men were more likely than women to endorse traditional male norms. These findings suggest that rigid gender role expectations contribute to harmful responses toward male victims and that interventions targeting these beliefs might help reduce such reactions.