Jersey Shore University Medical Center (JSUMC) is a 691-bed non-profit, tertiary research and academic medical center located in Neptune Township, New Jersey, servicing coastal New Jersey and the Central Jersey area. JSUMC is the region’s only university-level academic medical center. The hospital is part of the Hackensack Meridian Health Health System and is the system's second largest hospital. JSUMC is affiliated with the Robert Wood Johnson Medical School of Rutgers University, and Hackensack Meridian School of Medicine at Seton Hall University. JSUMC is also an ACS designated level II trauma center with a rooftop helipad handling medevac patients. Attached to the medical center is the K. Hovnanian Children's Hospital that treats infants, children, adolescents, and young adults up to the age of 21. JSUMC is listed as a major teaching and tertiary care hospital and has a staff of 127 interns and residents. It is a member of the Council of Teaching Hospitals and Health Systems.
ABSTRACT Severe hypertriglyceridemia (HTG) can interfere with laboratory assays. HTG‐induced pancreatitis usually presents with hypocalcemia, but the effect of severe HTG, with no associated pancreatitis, on calcium levels is not well described. We present a 25‐year‐old male with severe HTG and diabetes who presented with generalized weakness, nausea, and vomiting. His labs revealed a severely elevated triglyceride level, as well as a critically low total calcium of 2.8 mg/dL, but only mildly reduced ionized calcium (1.10 mmol/L), with no evidence of laboratory or imaging findings of pancreatitis. Hypocalcemia signs were positive on physical examination. Treatment for HTG led to rapid normalization of total calcium levels, while intravenous calcium gluconate normalized ionized calcium and resulted in symptom resolution. This case shows that severe HTG can cause significant total pseudohypocalcemia alongside mild true ionized hypocalcemia, highlighting the importance of monitoring ionized calcium in this setting.
The primary aim is to determine the clinical efficacy of pure hypochlorous acid solution (pHA) in preventing neonatal skin Staphylococcus aureus colonization. The secondary aim is to evaluate both the cutaneous and systemic safety and tolerability of full-body application of pHA. Neonates born at 22–41 weeks’ gestation were enrolled during three consecutive cohorts. A full-body wipe with pHA soaked gauze was performed three times a week. The incidence of colonization was then compared 6 months before and after intervention. The neonatal skin condition score, CMP, and LFTs were assessed. In total, 444 neonates received 1332 applications. There were 32 MRSA-positive colonizations pre-intervention and 15 after, with 53% decrease in the absolute number and a 47% decrease in the rate. There was minimal change in MSSA colonization. There were no signs of systemic or cutaneous toxicity. Cutaneous application of pHA decreases the incidence of MRSA colonization and demonstrates systemic and topical safety.
