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    中山大学

    中山大学

    Sun Yat-sen University
    院校EST. 1924
    27.5万论文总数
    333万引用总数

    论文量&引用量时间轴

    机构学者

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    Guihua Chen
    Guihua Chen
    The Third Affiliated Hospital, Sun Yat-Sen University
    论文:633引用:0H-index:0
    Xiaoshun He
    Xiaoshun He
    The First Affiliated Hospital, Sun Yat-sen University
    论文:577引用:0H-index:0
    Xueqing Yu
    Xueqing Yu
    Guangdong Provincial People's Hospital;School of Medicine, South China University of Technology
    论文:463引用:0H-index:0
    Yulong He
    Yulong He
    The First Affliated Hospital, Sun Yat-sen University;School of Medicine, Sun Yat-sen University;The Seventh Affiliated Hospital, Sun Yat-sen University
    论文:419引用:0H-index:0
    Zibin Zheng
    Zibin Zheng
    School of Software Engineering, Sun Yat-Sen University
    论文:385引用:0H-index:0
    Lijian Liang
    Lijian Liang
    The First Affiliated Hospital, Sun Yat-sen University
    论文:371引用:0H-index:0
    Minhu Chen
    Minhu Chen
    The First Affiliated Hospital of Sun Yat-sen University
    论文:364引用:0H-index:0
    Min Huang
    Min Huang
    School of Pharmaceutical Sciences, Sun Yat-sen University
    论文:359引用:0H-index:0
    Zhongdao Wu
    Zhongdao Wu
    Zhongshan School of Medicine, Sun Yat-sen University
    论文:322引用:0H-index:0

    论文(10000)

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    1Corrigendum to “development and Validation of a Sensitive LC-MS/MS Method for Determination of Gefitinib and Its Major Metabolites in Human Plasma and Its Application in Non-Small Cell Lung Cancer Patients” [J. Pharm. Biomed. Anal. 2019 Aug 5:172:364–371]
    Shaoxing Guan,Xi Chen, Fei Wang, Shuang Xin,Wei Feng,Xia Zhu,Shu Liu,Wei Zhuang,Shan Zhou,Min Huang,Xueding Wang,Li Zhang
    2027Journal of Pharmaceutical and Biomedical Analysis(2027)
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    2Robust Collision Prediction Neural Network Based on Η-Form Perceptron Against Visual Variability
    Yi Zheng, Hao Chen, Yusi Wang,Haiyang Li,Jigen Peng

    To construct the micro collision avoidance intelligent unit, efficient solutions have been pursued by modeling a specific collision-sensitive neuron, the lobula giant movement detector (LGMD), identified in the locust’s visual neural system. However, the existing LGMD models cooperating with a threshold-based collision avoidance strategy are less robust in the presence of visual variability, including fluctuations in contrast and noise. Intriguingly, biological research underscores the potential of the single-peak modeling through the η function, suggesting a non-threshold collision avoidance strategy by identifying the peak response moment. Adapting the biological finding to the engineering applications, we establish a novel modeling method based on η-form perceptron, making the response curve behave like the η function. The single peak within the η-function-form response occurs before the collision, offering reliable collision warning cues. Numerical experiments substantiate the effectiveness of the proposed model against visual variability. This study extends the limits of the applications of LGMD models in diverse scenarios, and explores the potential of modeling neural computation in constructing micro-intelligent units.

    2027Expert Systems with Applications(2027)
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    3A New Late Palaeocene Species of Syzygium (myrtaceae) from Southern Tibet with Insights on Its Paleobiogeographic History
    Yi Gao, Aixa Tosal,Ai Song, Jia Liu,Robert A. Spicer, Wei Chai, Xingyuan Qin, Xiaoting Xu,Gaurav Srivastava, Minyan Yu,Shufeng Li,Tao Su

    The Liuqu Formation in southern Tibet, China, archives the late Palaeocene Liuqu flora (ca. 56 Ma) and represents ancient vegetation on the northern margin of the Indian Plate near the India–Asia collision zone. It therefore provides critical evidence for evaluating early biotic interactions between India and Eurasia. Here, we report on Syzygium (Myrtaceae) fossil leaves from the Liuqu flora. Detailed morphological comparisons suggest that these specimens represent a new fossil species, namely Syzygium ovatum Y. Gao et T. Su sp. nov. By integrating fossil records with deep-time ecological niche modelling, we infer that Syzygium originated on the Indian Plate before or during the Palaeocene. By the middle Eocene, Syzygium had migrated to the northeast along the Asian Pacific coastline to East Asia, consistent with an “Out-of-India” dispersal scenario. Fossil evidence demonstrates that the genus reached New Zealand and Australia by the Early Miocene, likely through a Southeast Asian dispersal corridor. During the Pliocene, the distribution of Syzygium resembled that of its modern range. Although the African fossil record of Syzygium only dates to the early Pliocene, climatic suitability and favourable paleogeographic conditions suggest an earlier arrival: 1) during the Palaeocene via the Kohistan–Ladakh Island Arc and associated island systems or 2) during the Oligocene, when more suitable areas for Syzygium linked Africa and India. Generally, our results suggest a Palaeocene origin of Syzygium on the Indian Plate instead of an early Eocene Australian origin as previously proposed.

    2027Review of Palaeobotany and Palynology(2027)
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    4Similarity Analysis of Flow and Heat Transfer Characteristics in Fluid-to-Fluid Natural Circulation Loops
    W.B. Xiao, C.H. Dong, Z.B. Nan, B.H. Yan, L.S. Wang

    Fluid-to-fluid scaling provides an effective approach for investigating thermo-hydraulic systems employing working fluids that are difficult to study experimentally. In this study, the scaling methodology is applied to single-phase natural circulation loops (NCLs) and evaluated for both liquid–liquid (water–molten salt) and liquid–gas (water–helium) systems. A CFD model validated against available integral experimental data for the reference water loop is used to assess the scaling performance. Global similarity is assessed through dimensionless similarity criteria, while local thermo-hydraulic fields are analyzed to identify the mechanisms responsible for similarity distortions. The results show that the scaling law preserves the dominant global thermo-hydraulic characteristics for both fluid pairings, with the deviations of the principal operating parameters from their target similarity values remaining within approximately 3.5%. Moderate distortions in the secondary-side heat-transfer condition have a limited influence on the global circulation response. The remaining local distortions arise primarily from differences in thermo-physical properties that are not explicitly constrained by the scaling criteria, leading to more pronounced temperature and velocity deviations in the liquid–gas case. These deviations are associated mainly with differences in thermal diffusion and the resulting redistribution of buoyancy across the flow cross-section. The results clarify the applicability of unified fluid-to-fluid scaling for systems with substantially different thermo-physical properties and support the development of practical experimental approaches for such systems.

    2027Annals of Nuclear Energy(2027)
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    5Dynamic Pathologic Fusion: A Multimodal Framework for Integrating Global-Local Histopathology and Semantically Imputed Clinical Data
    Jie Zhang, Jiayuan Lei, Yani Wei, Jing Chen

    Multimodal pathological diagnosis is a critical paradigm for accurate clinical decision making. Despite substantial progress, existing weakly supervised multimodal pathological diagnostic approaches integrating whole-slide images(WSIs) and structured clinical data typically rely on predefined collaboration strategies that assume uniform modality reliability, failing to account for sample-wise modality-specific noise and quality variations. Under weak supervision, the lack of fine-grained instance-level annotations prevents reliable assessment of sample-wise modality reliability, causing unreliable modalities to be indiscriminately fused and amplified, leading to unstable representation learning and unreliable multimodal decision making. To address this challenge, we propose a confidence-based multimodal diagnostic framework that models sample-wise modality reliability via prediction confidence and incorporates it throughout representation learning and multimodal decision making. Specifically, a dual-path global-local attention mechanism suppresses attention noise and stabilizes confidence estimation in pathological image representations, while large language models(LLMs)-based semantic reasoning improves the quality and consistency of structured clinical data through clinically plausible missing value imputation. At the multimodal decision stage, prediction confidence is used as an indicator of modality reliability to guide adaptive fusion, preventing unreliable modalities from dominating predictions. Evaluated on CAMELYON16, TCGA-BRCA, and TCGA-NSCLC datasets, the proposed model demonstrates robust improvements. On the TCGA-NSCLC dataset, it achieves 93.36% Accuracy and 96.40% AUC, outperforming the best unimodal baseline by 4.86% and 2.11%. Furthermore, it consistently surpasses multimodal approaches with up to 1.42% accuracy improvements, proving its superior robustness under sample-wise modality noise. GitHub repository: https://github.com/KuaLe/Pathologic_Fusion.

    2027Expert Systems with Applications(2027)
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    合作机构(100)

    国立中山大学合作论文 5,990
    中国科学院合作论文 4,970
    南方医科大学合作论文 3,856
    北京大学合作论文 3,682
    暨南大学合作论文 3,531
    广州医科大学合作论文 2,800
    华南理工大学合作论文 2,291
    复旦大学合作论文 2,267
    上海交通大学合作论文 2,219
    浙江大学合作论文 2,106

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