
The case of a woman with angioleiomyolipoma is reported. In the light of published data a brief review is presented on the aetiology, pathology and clinical aspects of this extremely rare disease. Angioleiomyolipoma is a benign disease which can be cured by removal of the kidney. In the case at issue, there occurred no tuberous sclerosis in the patient.
The effect of low-output He-Ne laser rays on the survival of mouse lymphoma P388 cell cultures was studied on the basis of the colony forming ability. Irradiation with 1.3 and 9 joule of 5 and 10 mW He-Ne lasers, respectively, seemed to cause a relatively low cell necrosis. The survival curve did not show the shape characteristic of ionizing radiation.
After a brief review of the literature on the epidermoid cyst of the testicle, the aspects of the disease are discussed. It stressed that castration is an unavoidable part of the treatment of this type of cyst.
Nineteen cases of tumours arising in the skeletal muscles and 22 cases of tumours arising in tendons seen over 15 years (1967-1981) are surveyed. Malignant tumours occurred most frequently in lower limb muscles and tendons, while benign tumours in the tendons of the hands.
The diagnostic problems and treatment of acute suppurative nephritis are discussed on the basis of 146 patients. The biological properties of the pathogens isolated from urine and their manifestation with clinical symptoms are discussed. The role of incorrectly prescribed antibiotics in changing the characteristic symptoms and thus making diagnosis difficult is stressed. It appears from the material that in 20% of the operated patients all x-ray and laboratory tests gave negative results, despite the fact that in the course of operation abscesses were detected under the renal capsule. In 60% of the cases x-rays supplied reliable information for the indication of surgical intervention. The history of fever and shaking fits and the progression revealed by careful observation of the patients are considered the most important information needed for deciding for surgery.
The methods applicable to the diagnosis of polycystic kidney disease are reviewed. By assessing the clinical data of 314 patients suffering from adult polycystic kidney disease who had been treated in the 30 years between 1950 and 1979, the importance of conservative therapy and nephrological care is emphasized. The significance of hemodialysis in therapy and the special circumstances of transplantation are discussed. The indication of surgical treatment can be extended in complication-free cases.
Comparative tests were performed in animal experiments with traditional and new suture materials placed into the pancreas. Dexon and polyester caused the least tissue reaction and their reaction indices were the most favourable. These threads therefore appear the most suitable for making sutures in the pancreas.
The combination with a malignant tumour of angioneurotic oedema (ANO) elicited by a disturbance of the complement system was studied. After surgical removal of the tumour the pathologic complement component level may become normal and the angioneurotic oedema may disappear. In the reported case an angioneurotic oedema, the disturbance of the complement component and scintigraphic deviations of the thyroid suggested the presence of a thyroid carcinoma. After thyroidectomy the ANO disappeared and the complement component returned to normal. This case draws attention to the possibility that, beside lymphoproliferative and autoimmune diseases and cancer of the rectum, carcinoma of the thyroid may also be in the background of angioneurotic oedema.
On the basis of studies performed during the past two decades primary malignant melanoma can now be recognized in over 90% of the cases. The clinician, the nurse and even the patient can be taught to recognize the lesions early while histology is able to reveal the important prognostic factors, such as growth phase, depth of invasion and tumour thickness. This allows to identify the patients at high risk of developing occult metastases in regional lymph nodes. Early diagnosis and surgical treatment of melanoma are now the only acceptable approach and therefore all physicians must be on the alert for the condition.
In 26 dogs, pH and K+-concentration measured continuously on the surface of the liver. The same decrease of pH and increase of the K+-concentration was found after ligation of the hepatic artery as when arterial and portal circulations were suspended. Reperfusion restored normal conditions even after 45 minutes of circulatory arrest. Arterialization of the portal vein abolished the effect of the ligation of the hepatic artery.
In the preparation of colorectal operations, beside the mechanical cleaning of the bowels, orally administered metronidazole, acting on anaerobic bacteria, was found to be highly effective. Compared to the controls, the drug considerably reduced the number and severity of postoperative infections, and, consequently, also the mortality. With metronidazole prophylaxis no wound suppuration indicating anaerobic infection was noted. The combined application of metronidazole with some antibiotic acting on the aerobic bacteria of the intestinal flora resulted in a significant reduction of postoperative infections.
In the open chest the heart loses more heat and its epicardiac temperature will fundamentally depend upon the temperature of the body and its environment, upon the flow in the coronaries and upon the actual state of myocardial metabolism. The experiments were carried out with the AGA Thermovision Type 750 equipment. The epicardial temperature changes induced by reactive hyperaemia due to the temporary coronary ligation in 24 dogs, and by permanent coronary ligation in 70 dogs, as well as by the gradually reduced coronary flow of another 8 dogs were recorded by means of thermography. The results indicated a relationship between the changes in epicardial flow and epicardial temperature, consequently thermography is considered a method suitable for the study of myocardial flow.
The operational techniques of invaginational, two-layer and one-layer direct ureteroileal anastomoses were studied in 60 dogs. The results were checked by means of radiologic and histologic methods. When the stump of the ureter is intact, direct ureteroileal anastomosis seems to be more favourable from the aspect of restoration of the urine passage and protection of the renal parenchyma.
The simultaneous occurrence of Graves' disease with ophthalmopathy lymphocytic and subacute de Quervains' thyroiditis has been observed in two male patients suffering from follicular-type thyroid carcinoma. In one of them Sjögren syndrome and a mild form of diabetes were also diagnosed. It is assumed, on the basis of indirect evidence, that the humoral and cellular lesions determined by genetic factors and influenced by prolonged thyrostatic and steroid treatment are jointly responsible for tumour genesis.