OBJECTIVES:Pre-eruptive intracoronal resorption (PEIR) is a pathological condition lacking standardized treatment guidelines. This systematic review aims to synthesize published evidence on PEIR treatment strategies. MATERIALS AND METHODS:Five databases (PubMed, Web of Science, Scopus, Embase, and Dentistry & Oral Sciences Source) were searched according to a registered PROSPERO protocol (CRD420251018329, 28 March 2025). Eligible studies were case reports and case series describing PEIR treatment and follow-up. Methodological appraisal used the Joanna Briggs Institute Critical Appraisal Checklists for Case Reports and Case Series. RESULTS:Forty-six studies (35 case reports and 11 case series) were included. Treatment varied according to lesion size, eruption status, and pulpal involvement, ranging from observation/sealants (12 cases) to restoration (14), surgical exposure (12), vital pulp/endodontic therapy (9), and extraction (14). CONCLUSIONS:Published case reports and case series describe a range of management approaches for PEIR, with variable clinical and radiographic outcomes. However, the available evidence does not permit reliable estimates of treatment success, failure, recurrence, or prognosis, nor comparison of the effectiveness of different management approaches. Early radiographic detection and careful follow-up may facilitate timely intervention, but further multicenter studies are needed to establish evidence-based management recommendations.
BACKGROUND:Poor compliance with conventional oral analgesics can compromise post-extraction pain management in children. Understanding parental perceptions of innovative therapeutic approaches may support the development of acceptable postoperative pain management strategies. AIM:To assess parental perceptions regarding the potential use of analgesic ice cream as a postdental extraction therapeutic modality for children using a mixed-method approach. DESIGN:An explanatory sequential mixed-method study was conducted among 421 parents using a validated questionnaire (Cronbach's α = 0.82), followed by semi-structured interviews with 26 parents. Quantitative data were analyzed using descriptive statistics, Chi-square tests, and binary logistic regression, while qualitative data underwent thematic analysis. RESULTS:Most parents showed favorable perceptions toward analgesic ice cream, with 72.2% expressing willingness to use it following dental extraction. Perceived benefits included improved compliance, ease of administration, and enhanced postoperative comfort. Key concerns involved safety, dosage accuracy, and overconsumption. Qualitative findings supported these perceptions while highlighting the importance of professional recommendation, clear instructions, and scientific validation. CONCLUSION:Parents generally perceived analgesic ice cream as a potentially acceptable adjunct to postoperative pain management in children. However, concerns regarding safety, dosage regulation, and professional guidance warrant consideration in future formulation development and clinical evaluation.
INTRODUCTION:Children with more caries in the primary dentition have been observed to have greater caries risk in the permanent dentition. In a previous trial, we determined lesion arrest in primary teeth, where 38% SDF gel and 2.5% NaF varnish were applied sequentially. This follow-up study determined the prevalence of children with any caries in untreated first permanent molars. MATERIALS AND METHODS:The design was a retrospective cohort. Participants were drawn from five Centros Educativos Iniciales, Puno, Peru. Examinations were conducted 19 months after the second treatment. Any caries prevalence (D2-4MFS > 0) and D2-4MFS were compared between groups. RESULTS:The exposed group was 219 children in the initial trial; the unexposed group was in the same classes but did not participate. 181/237 (76.4%) children treated at baseline were followed up; 104 unexposed children were examined. Prevalence of any caries in first permanent molars was lower in exposed children (4.4%, 95% CI 1.4, 10) compared to unexposed (66.6%, 95% CI 53.6, 77.2; p < 0.001). D2-4MFS in first permanent molars was lower in the exposed (median [IQR] = 0 [0, 0]) vs. unexposed (median [IQR] = 1 [0, 3]; p < 0.001). DISCUSSION:Children who received two sequential applications of SDF gel/NaF varnish at 3-4y were observed to have fewer caries in first permanent molars at 6-7 y than unexposed children.
BACKGROUND:Evidence comparing toothbrush designs and the influence of children's developmental abilities on brushing performance is limited. AIM:To compare the plaque-removal efficacy of three toothbrush types in 7-year-old children and to assess whether developmental characteristics affect brushing performance. DESIGN:This single-blind, randomized, three-period crossover clinical trial included 60 typically developing 7-year-old children. Participants used a conventional manual, triple-headed manual, and rechargeable powered toothbrush in randomized order with washout periods. Plaque was assessed using the modified Quigley-Hein Plaque Index and the Approximal Plaque Index. Developmental characteristics were evaluated using the parent-reported Five-to-Fifteen questionnaire. RESULTS:Mean plaque reduction differed significantly among toothbrush types. Powered (1.833 ± 0.705) and triple-headed manual toothbrushes (1.802 ± 0.678) achieved greater plaque reduction than the conventional manual toothbrush (1.310 ± 0.563; both p < 0.001), with no difference between powered and triple-headed brushes (p = 0.963). Approximal plaque removal was highest with the powered toothbrush, reaching 75% complete removal on posterior vestibular surfaces (p ≤ 0.016). Children with gross motor difficulties showed lower reduction with the powered toothbrush than children without such difficulties (p = 0.048). CONCLUSION:Powered and triple-headed toothbrushes are more effective than conventional manual brushes in 7-year-old children, with equivalent efficacy. Exploratory analyses suggest gross motor skills may influence powered toothbrush performance, warranting confirmation in adequately powered studies. TRIAL REGISTRATION:The study was registered retrospectively with the Australian New Zealand Clinical Trials Registry (ANZCTR; ACTRN12626000023358).
BACKGROUND:Rhabdomyomatous hamartoma is a rare congenital lesion, usually described on the face and neck and infrequently found in the oral cavity. Because its clinical presentation is non-specific, histopathological examination plays a fundamental role in establishing the final diagnosis and determining appropriate therapeutic management. CASE REPORT:An 8-year-old male patient presented with a submucosal nodule on the left lateral border of the tongue. The initial diagnostic hypothesis was dermoid cyst; however, histopathological examination revealed thick, interlacing bundles of skeletal striated muscle, compatible with rhabdomyomatous hamartoma. CONCLUSION:Although rare, rhabdomyomatous hamartoma should be considered in the differential diagnosis of oral nodules in children. Histopathological confirmation is essential for accurate diagnosis and as a guide to treatment, helping to avoid unnecessary interventions and ensuring proper management of the lesion.
INTRODUCTION:A scoping review of dietary advice for caries prevention in adolescents in high income English-speaking countries was conducted. OBJECTIVE:To identify and appraise dietary advice for dental settings in government or private sector. METHOD:Dentistry and Oral Sciences database was searched from 2015 to September 2023. Papers published between 2015 and 2021 were identified from an existing review of nutrition practices not reporting dietary advice. A MEDLINE, CINAHL, Embase search (2021-September 2023) was also conducted. An advanced Google searches of relevant professional and dental commercial websites was conducted. RESULTS:Ten of 1257 identified papers were included, containing 17 topics of dietary advice: most common was to drink water (5/10), and keep sugars to mealtimes (4/10). Twenty-nine out of 63 national professional organisation yielded 18 topics of advice. Other websites (88 of 90) presented 14 topics of advice. Most common was 'drink water' (28/29 professional, 50/88 other websites) and 'drink milk' (18/29 professional, 28/88 other websites). Information on sugars thresholds ranged from 6 to 18.75 teaspoons/day. Definitions of 'low sugar' ranged from 5 to 15 g/100 g. CONCLUSION:In HIC English-speaking countries, the most common dietary advice for caries prevention in adolescents promotes water and milk and discourages sugars in-between meals. Confusion exists on sugars thresholds and what constitutes 'low sugar'.
BACKGROUND:Molar Incisor Hypomineralization (MIH) is challenging for Pediatric Dentists. AIM:To assess the perception and experience of dentists from the Brazilian Unified Health System (UHS) regarding clinical management of MIH. DESIGN:This cross-sectional study was based on a questionnaire including sociodemographic data, perception and treatment decision, and continuing education. The questionnaire scores and independent variables were tested using Student's t-test, ANOVA, and Poisson regression. RESULTS:The sample comprised 304 dentists. Among available restorative options in the UHS setting, glass ionomer cement was the first choice for severe MIH (65.1% for case 1; 48.4% for case 2). When asked about their first choice when other options were available, indirect restorations (38.9%) and composite (37.2%) were the most preferred. Only 8.9% had used the Hall Technique, but 52% would use it if available. The scale of perception of MIH as a clinical problem resulted in 22.7 (SD = 5.12), being higher among pediatric dentists (PR: 1.23; 95% CI: 1.12-1.33; p < 0.001) and dentists working in the Mountain region of the state (PR: 1.09; 95% CI: 1.001-1.179; p < 0.001). CONCLUSION:UHS dentists frequently treat patients with MIH, acknowledge its clinical implications, and recognize it as a challenge within the UHS.
BACKGROUND:Perinatal and neonatal factors associated with developmental defects of enamel (DDE) among children born prematurely have not been well studied. AIM:To evaluate perinatal and neonatal factors associated with DDE in primary dentition among children born prematurely. DESIGN:A prospective observational study was performed including ≤ 32 weeks gestational age (GA) infants within 12 h after birth. Infants with TORCH infections, chromosomal disorders, craniofacial anomalies, inherited anomalies of teeth, organic acidemia, or who died were excluded. At 3 years of corrected age, DDE was evaluated using the modified DDE index. RESULTS:One hundred and eighty-three infants were studied of which 77 developed DDE. GA was inversely associated with DDE (OR 0.86, 95% CI: 0.75-0.99, p = 0.04). On multivariate logistic regression, maternal diabetes (OR 3.4, 95% CI: 1.05-11.2, p = 0.04), preeclampsia (OR 0.32, 95% CI: 0.15-0.73, p = 0.006), respiratory distress syndrome (RDS, OR 2.44, 95% CI: 1.05-5.7, p = 0.03), and days on furosemide (OR 1.02, 95% CI: 1.001-1.04, p = 0.04) were associated with DDE. CONCLUSION:DDE in primary dentition is common among children born prematurely with incidence directly related to the degree of prematurity. Maternal diabetes, RDS, and days on furosemide may be risk factors, whereas preeclampsia may be protective for DDE.
BACKGROUND:Stainless steel crowns (SSCs) are the standard for restoring severely damaged primary teeth, but esthetic concerns and metal hypersensitivity have driven interest in alternatives. Bioflx crowns (BFCs) are flexible, metal-free restorations with uncertain comparative performance. AIM:To evaluate the clinical and in vitro performance of BFCs versus SSCs, zirconia crowns (ZrCs), and other pediatric crown systems (Figaro, PEEK, Edelweiss, and graphene-based). DESIGN:This PRISMA-based systematic review searched PubMed/MEDLINE, Scopus, Web of Science, Cochrane, Embase, and Google Scholar. Comparative clinical and in vitro studies were included. Risk of bias was assessed using Cochrane ROB-2 and modified CONSORT tools. RESULTS:Twenty-six studies (nine clinical and 17 in vitro) were included. BFCs showed variable fracture resistance, favorable stress distribution, and less antagonist enamel wear than ZrCs, but lower, cement-dependent retention compared with SSCs. Clinically, BFCs demonstrated high short-term survival (> 90%), comparable gingival health, and higher parental satisfaction, with an overall low-to-moderate risk of bias. CONCLUSIONS:Bioflx crowns show promising short-term performance as an esthetic prefabricated option for primary teeth. Although SSCs remain superior in retention with conventional cementation, and Hall technique support is not yet validated for BFCs, BFCs offer esthetic, antagonist-preserving, and clinical efficiency advantages. Evidence remains limited, warranting cautious interpretation and long-term RCTs. Trial Registration This systematic review was prospectively registered in PROSPERO (CRD420251083036).
BACKGROUND:Computer-controlled anesthesia delivery systems (CCLADs), such as SleeperOne, are available as an alternative to traditional anesthesia for the treatment of teeth with molar incisor hypomineralization (MIH). AIM:This study aimed to evaluate the effects of the SleeperOne and the conventional local anesthesia technique on pain and anxiety in children with MIH. DESIGN:Twenty-eight children aged 6-12 were included in the study. Patients were divided into 2 groups (n = 28): Conventional anesthesia group and SleeperOne group. The Children's Fear Survey Schedule-Dental Subscale (CFSS-DS) was administered to all participants prior to treatment. Pain and anxiety levels were assessed using both objective measures (pulse rate, oxygen saturation [SpO2], and salivary cortisol levels) and subjective scales (Wong-Baker Pain Rating Scale [WBS], Visual Analog Scale [VAS], and Face, Legs, Activity, Crying, Consolability Scale [FLACC]). RESULTS:Cortisol levels were significantly higher in the conventional anesthesia group (p < 0.001). In the after treatment values, mandibular cortisol levels in participants without hypersensitivity and total cortisol levels in participants with hypersensitivity were significantly lower in the SleeperOne anesthesia group (p = 0.009 and p = 0.017). CONCLUSIONS:Lower salivary cortisol levels, a physiological marker of stress, were observed in the SleeperOne group during the treatment of MIH-affected teeth. TRIAL REGISTRATION:ClinicalTrials.gov: NCT07268157.
BACKGROUND:Although community-based programs are implemented to promote children's oral health, evidence regarding their impact on oral health-related quality of life (OHRQoL) remains limited. AIM:To evaluate changes in OHRQoL among schoolchildren following participation in a community-based oral health program and to identify factors associated with post-intervention OHRQoL. DESIGN:This observational pre-post study included 668 schoolchildren in Seoul, South Korea, participating in the Student Dental Home Program. OHRQoL was assessed before and after the program using the Korean COHIP-SF 19. Changes in scores were analyzed using paired t-tests, and factors associated with post-intervention OHRQoL were examined using ANCOVA and linear regression analyses. RESULTS:Total scores increased significantly (mean difference 3.7, 95% CI 3.3-4.1; Cohen's d = 0.66). Significant increases were observed across all subscales, with the largest effect in the Oral Health subscale (d = 0.81). In the simple regression analyses, spontaneous tooth pain, gingival bleeding, halitosis, and malocclusion were associated with lower scores. In the multivariable model, malocclusion remained the only factor independently associated with lower scores (B -0.66, 95% CI-1.37 to -0.01, p = 0.048). CONCLUSIONS:OHRQoL scores increased following participation in a community-based oral health program. Malocclusion remained independently associated with lower post-intervention OHRQoL after baseline adjustment.
