For the purpose of describing a new case of the Woringer-Kolopp disease, we are up-dating the problem and its classification and contributing clinical, histopathological, and ultrastructural facts which show that this is a lymphoma of the T cells and therefore should be classified along with the mycosis fungoides and the Sézary syndrome. The identification test of the lymphocytes and the ultrastructural study bring to light new facts of this disease.
We read with interest the vignette by Spier et al1in the February 1995 issue of theArchivesconcerning recurrent leg ulcerations as the initial clinical manifestation of Klinefelter's syndrome. We completely agree with their conclusion that it is important to consider Klinefelter's syndrome in young male patients with chronic leg ulcers. We must also realize that this chromosomal abnormality is far from rare. Its prevalence has been estimated at one male birth in 500.2Up to now, it is not exactly known which percentage of all patients with Klinefelter's syndrome actually have leg ulcers. We recently diagnosed several patients with Klinefelter's syndrome; their presenting symptom was recurrent leg ulcers. Further investigation into the pathogenesis of skin symptoms and ulcers showed that some of these patients even lack the underlying venous insufficiency. The reported platelet hyperaggregability was not present in our group of patients with Klinefelter's syndrome. Therefore,
