Gastroesophageal reflux disease (GERD) is a known contributor to chronic hoarseness. This study aimed at determining the prevalence of GERD in patients with idiopathic hoarseness using endoscopy and 24-h impedance pH monitoring and to assessing associated acoustic voice parameters. In this prospective study, 242 patients with hoarseness were screened, of which 40 (n = 40) with idiopathic hoarseness were selected for detailed evaluation. All underwent video laryngoscopy, acoustic voice analysis, esophagogastroduodenoscopy, esophageal manometry and 24-h impedance pH-metry. GERD diagnosis was based on findings such as LA grade B/C/D esophagitis, Barrett’s esophagus, peptic strictures or abnormal acid exposure time and DeMeester scores. Acoustic parameters including jitter, shimmer and noise-to-harmonics ratio (NHR) were analyzed. Among 40 participants selected for evaluation, GERD was diagnosed in 25 (62.5
Acute upper gastrointestinal bleeding (AUGIB) is a frequent life-threatening scenario in everyday clinical practice. We undertook a study to assess the etiology and important clinical outcomes in patients with significant AUGIB unstable for transfer to an endoscopy suite. This is a prospective observational study conducted between December 2019 and December 2022, including patients above the age of 16 years with a history of clinically significant AUGIB undergoing bedside endoscopy in an intensive care (ICU)/high dependency unit (HDU) setting. Seventy patients with a mean age (SD) of 51.27 (13.45) years were included. The initial mean (SD) hemoglobin, APACHE score, SOFA score and GCS of these patients were 6.71 (2.14) g
The impact of sarcopenia on the clinical outcomes following gastric variceal (GV) hemorrhage in cirrhosis remains unclear. We retrospectively analyzed patients with cirrhosis and GV bleeding from six centers in India (January 2017–January 2023). Baseline demographics, further decompensation events—rebleeding, ascites and hepatic encephalopathy (HE) and mortality—were reviewed. Cross-sectional imaging was used to assess skeletal muscle index (SMI). Sarcopenia was defined using gender-specific SMI thresholds (men, < 42 cm2/m2 and women, < 38 cm2/m2). Competing risk analysis was used to evaluate predictors of rebleeding and further decompensation with mortality as a competing event. Total 318 patients (214 males, 67.3
