A new lignan, (+)-nortrachelogenin (I), and a known compound, daphnoretin were isolated from Wikstroemia indica C. A. Meyer (Thymelaeaceae). The structure of (+)-nortrachelogenin was established as 8(R), 8'(R)-4,4',8'-trihydroxy-3,3'-dimethoxylignan-olid(9, 9') on the basis of spectroscopic evidence and comparison with its enantiomer, (-)-nortrachelogenin. (+)-Nortrachelogenin (I) showed effects on the central nervous system producing depression in rabbits.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTXanthocillin, A Metabolite of Eupenicillium Egyptiacum NRRL 1022R. F. VesonderCite this: J. Nat. Prod. 1979, 42, 2, 232–233Publication Date (Print):March 1, 1979Publication History Published online1 July 2004Published inissue 1 March 1979https://pubs.acs.org/doi/10.1021/np50002a016https://doi.org/10.1021/np50002a016research-articleACS PublicationsRequest reuse permissionsArticle Views167Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Several hundred flavonoid derivatives, natural and synthetic, which have been tested in the screening program of the National Cancer Institute, have been examined for indications of structure-activity relationships which might exist among these compounds. No such relationships are apparent. In spite of occasional activity these compounds do not warrant further detailed pursuit as anti-tumor agents.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Wax Hydrocarbons of Scutellaria Lateriflora L.M. S. Yaghmai and G. G. BensonCite this: J. Nat. Prod. 1979, 42, 2, 228–230Publication Date (Print):March 1, 1979Publication History Published online1 July 2004Published inissue 1 March 1979https://doi.org/10.1021/np50002a014RIGHTS & PERMISSIONSArticle Views87Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (220 KB) Get e-Alerts Get e-Alerts
The tropical weed Bidens pilosa L. (Asteraceae) contains a number of polyacetylenes which are phototoxic to bacteria, fungi, and human fibroblast cells in the presence of sunlight, artificial sources of long-wave ultraviolet light, or cool-white fluorescent light. The principle photoactive compound in the leaf, phenylheptatriyne, is present in the cuticle as well as in the underlying cells. Experiments with calf thymus DNA indicate that, unlike photoactive furanocoumarins, phenylheptatriyne does not form interstrand cross linkages with DNA in ultraviolet light.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCyanogenic Plants From ArgentinaDavid S. Seigler, Jorge D. Coussio, and Rubén V. D. RondinaCite this: J. Nat. Prod. 1979, 42, 2, 179–182Publication Date (Print):March 1, 1979Publication History Published online1 March 1979Published inissue 1 March 1979https://pubs.acs.org/doi/10.1021/np50002a008https://doi.org/10.1021/np50002a008research-articleACS PublicationsRequest reuse permissionsArticle Views80Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Occurrence of Tryptamine and N-Methyltryptamine in Mimosa somniansM. P. Gupta, T. D. Arias, J. Etheart, and G. M. HatfieldCite this: J. Nat. Prod. 1979, 42, 2, 234–236Publication Date (Print):March 1, 1979Publication History Published online1 July 2004Published inissue 1 March 1979https://pubs.acs.org/doi/10.1021/np50002a017https://doi.org/10.1021/np50002a017research-articleACS PublicationsRequest reuse permissionsArticle Views172Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTControl of Ecdysterone Biogenesis in Tissue Cultures of Trianthema portulacastrumG. A. Ravishankar and A. R. MehtaCite this: J. Nat. Prod. 1979, 42, 2, 152–158Publication Date (Print):March 1, 1979Publication History Published online1 July 2004Published inissue 1 March 1979https://pubs.acs.org/doi/10.1021/np50002a003https://doi.org/10.1021/np50002a003research-articleACS PublicationsRequest reuse permissionsArticle Views137Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAlkaloids of Papaver Genus XI. Alkaloids of Glaucium vitellinum, Population IsfahanA. Shafiee, A. Ghanbarpour, I. Lalezari, and S. LajevardiCite this: J. Nat. Prod. 1979, 42, 2, 174–178Publication Date (Print):March 1, 1979Publication History Published online1 July 2004Published inissue 1 March 1979https://pubs.acs.org/doi/10.1021/np50002a007https://doi.org/10.1021/np50002a007research-articleACS PublicationsRequest reuse permissionsArticle Views146Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDimeric Aporphine-Benzylisoquinoline and Aporphine-Pavine AlkaloidsHélène Guinaudeau, Michel Leboeuf, and André CavéCite this: J. Nat. Prod. 1979, 42, 2, 133–149Publication Date (Print):March 1, 1979Publication History Published online1 July 2004Published inissue 1 March 1979https://pubs.acs.org/doi/10.1021/np50002a001https://doi.org/10.1021/np50002a001research-articleACS PublicationsRequest reuse permissionsArticle Views242Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCyclopeptide Alkaloids. Phencyclopeptines From Ceanothus sanguineusJ. Clark Lagarias, Dane Goff, and Henry RapoportCite this: J. Nat. Prod. 1979, 42, 6, 663–668Publication Date (Print):November 1, 1979Publication History Published online1 July 2004Published inissue 1 November 1979https://pubs.acs.org/doi/10.1021/np50006a013https://doi.org/10.1021/np50006a013research-articleACS PublicationsRequest reuse permissionsArticle Views143Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Caryachnine N-Methosalt From Cryptocarya chinensis and PMR Spectral Characteristics of Some Quaternary Pavine AlkaloidsChung-hsiung Chen, Shoei-shen Lee, Chung-fang Lai, Jinn Wu, and Jack L. BealCite this: J. Nat. Prod. 1979, 42, 2, 163–167Publication Date (Print):March 1, 1979Publication History Published online1 July 2004Published inissue 1 March 1979https://doi.org/10.1021/np50002a005RIGHTS & PERMISSIONSArticle Views124Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (381 KB) Get e-Alerts Get e-Alerts
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsolation of 11-Hydroxyated Kauranic Acids From Adenostemma laveniaPing C. Cheng, Charles D. Hufford, and Norman J. DoorenbosCite this: J. Nat. Prod. 1979, 42, 2, 183–186Publication Date (Print):March 1, 1979Publication History Published online1 July 2004Published inissue 1 March 1979https://pubs.acs.org/doi/10.1021/np50002a009https://doi.org/10.1021/np50002a009research-articleACS PublicationsRequest reuse permissionsArticle Views170Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Lower Terpenoids of Isocoma wrightiiL. H. Zalkow, R. N. Harris, III., and N. I. BurkeCite this: J. Nat. Prod. 1979, 42, 1, 96–102Publication Date (Print):January 1, 1979Publication History Published online1 July 2004Published inissue 1 January 1979https://doi.org/10.1021/np50001a004RIGHTS & PERMISSIONSArticle Views331Altmetric-Citations30LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (595 KB) Get e-Alerts Get e-Alerts
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPatulitrin and Acetyl Patulitrin, Flavonol Glycosides From Lagascea mollisS. F. El-Naggar and R. W. DoskotchCite this: J. Nat. Prod. 1979, 42, 1, 126–128Publication Date (Print):January 1, 1979Publication History Published online1 July 2004Published inissue 1 January 1979https://pubs.acs.org/doi/10.1021/np50001a009https://doi.org/10.1021/np50001a009research-articleACS PublicationsRequest reuse permissionsArticle Views165Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Benzofurans of Isocoma wrightii. Structure and StereochemistryL. H. Zalkow, B. A. Ekpo, L. T. Gelbaum, R. N. Harris, III., E. Keinan, J. R. Novak, Jr., C. T. Ramming, and D. Van DerveerCite this: J. Nat. Prod. 1979, 42, 2, 203–219Publication Date (Print):March 1, 1979Publication History Published online1 July 2004Published inissue 1 March 1979https://pubs.acs.org/doi/10.1021/np50002a012https://doi.org/10.1021/np50002a012research-articleACS PublicationsRequest reuse permissionsArticle Views173Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTComparative Sterols Composition of the Red Alga Asparagopsis armata and Its Tetrasporophyte Falkenbergia rufolanosaGeorges Combaut, Yves Bruneau, Louis Codomier, and Jean TesteCite this: J. Nat. Prod. 1979, 42, 2, 150–151Publication Date (Print):March 1, 1979Publication History Published online1 July 2004Published inissue 1 March 1979https://pubs.acs.org/doi/10.1021/np50002a002https://doi.org/10.1021/np50002a002research-articleACS PublicationsRequest reuse permissionsArticle Views158Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Latex of Euphorbia tirucalli, collected in Colombia, yielded 12-O-2Z-4E-octadienoyl-4-deoxyphorbol-13-acetate (1), which exhibited an irritant potency equivalent to that of the standard irritant, phorbol-12-tetradecanoate-13-acetate, in a mouse ear test system. The unsaturated 4-deoxyphorbol diesters recently reported in E. tirucalli grown in South Africa were not observed in the present study.
Benzophenanthridine alkaloids, fagaronine 4, O-methylfagaronine 5,nitidine 1, allonitidine 3 and methoxydihydronitidine 2 have been shown to possess inhibitory activity against reverse transcriptase of RNA tumor viruses. The enzyme inhibition (50%) by these alkaloids was found in the range of 6-60 microgram per milliliter of the reaction mixture when polynucleotide-oligodeoxynucleotide complexes were used as template primers. The results suggested that the benzophenanthridine alkaloids interacted with the template primers (particularly of the A:T base pairs) and not with the enzyme proteins. Kinetics reaction of the reverse transciptase inhibition showed that the alkaloids stopped the DNA polymerase synthesis instantly, probably by interacting with the template primer.
