Transactions of the New York Academy of SciencesVolume 41, Issue 1 Series II p. 243-251 Fifty Years of Developmental Genetics†‡ SALOME GLUECKSOHN-WAELSCH, SALOME GLUECKSOHN-WAELSCH Department of Genetics Albert Einstein College of Medicine Bronx, New York 10461Search for more papers by this author SALOME GLUECKSOHN-WAELSCH, SALOME GLUECKSOHN-WAELSCH Department of Genetics Albert Einstein College of Medicine Bronx, New York 10461Search for more papers by this author First published: August 1983 https://doi.org/10.1111/j.2164-0947.1983.tb02806.xCitations: 1 † Delivered on May 5, 1982 as the Fourth L.C. Dunn Lecture under the sponsorship of the New York Blood Center. ‡ This work was supported by Grants GM-27250 and GM-19100 from the National Institutes of Health and by Grant CD-38 from the American Cancer Society. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume41, Issue1 Series IIAugust 1983Pages 243-251 RelatedInformation
Transactions of the New York Academy of SciencesVolume 41, Issue 1 Series II p. 25-34 Lipid-Specific Toxins From Bacteria, Insects, and Marine Invertebrates† ALAN W. BERNHEIMER, ALAN W. BERNHEIMER Department of Microbiology New York University School of Medicine New York, New York 10016Search for more papers by this author ALAN W. BERNHEIMER, ALAN W. BERNHEIMER Department of Microbiology New York University School of Medicine New York, New York 10016Search for more papers by this author First published: August 1983 https://doi.org/10.1111/j.2164-0947.1983.tb02780.xCitations: 3 † This paper is adapted from work presented at the Symposium on Toxins and Lectins held in Pretoria, Republic of South Africa, July 26 to 28, 1982, sponsored by the International Union of Biological Sciences; my own work in this paper was supported by Public Health Service Grant AI-02874 and by Public Health Career Program Award 5K06-A1-14–198, both from the National Institute of Allergy and Infectious Diseases. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Bernheimer, A. W. & L. L. Schwartz. 1965. J. Pathol. Bacteriol. 89: 209–223. 10.1002/path.1700890121 CASPubMedWeb of Science®Google Scholar 2 Thelestam, M. & R. Mollby. 1979. Biochim. Biophys. Acta 557: 156–169. 10.1016/0005-2736(79)90098-1 CASPubMedWeb of Science®Google Scholar 3 Bernheimer, A. W. 1976. In Mechanisms in Bacterial Toxinology. A. W. Bernheimer, Ed.: 85. Wiley, New York, NY. Google Scholar 4 Habermann, E. 1972. 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Transactions of the New York Academy of SciencesVolume 41, Issue 1 Series II p. 173-182 Properties of Acyl Coenzyme A: 1-Acyl-sn-Glycerol 3-Phosphate Acyltransferase from Rat Liver Mitochondria and Microsomes† DIPAK HALDAR, DIPAK HALDAR Department of Biochemistry The Public Health Research Institute of the City of New York, Inc. New York, New York 10016 Present address: Department of Biological Sciences, St. John's University, Jamaica, New York 11439.Search for more papers by this authorHANNA CHROBOCZEK KELKER, HANNA CHROBOCZEK KELKER Department of Biochemistry The Public Health Research Institute of the City of New York, Inc. New York, New York 10016 Present address: Department of Microbiology, New York University Medical Center, New York, New York 10016.Search for more papers by this authorMAYNARD E. PULLMAN, MAYNARD E. PULLMAN Department of Biochemistry The Public Health Research Institute of the City of New York, Inc. New York, New York 10016Search for more papers by this author DIPAK HALDAR, DIPAK HALDAR Department of Biochemistry The Public Health Research Institute of the City of New York, Inc. New York, New York 10016 Present address: Department of Biological Sciences, St. John's University, Jamaica, New York 11439.Search for more papers by this authorHANNA CHROBOCZEK KELKER, HANNA CHROBOCZEK KELKER Department of Biochemistry The Public Health Research Institute of the City of New York, Inc. New York, New York 10016 Present address: Department of Microbiology, New York University Medical Center, New York, New York 10016.Search for more papers by this authorMAYNARD E. PULLMAN, MAYNARD E. PULLMAN Department of Biochemistry The Public Health Research Institute of the City of New York, Inc. New York, New York 10016Search for more papers by this author First published: August 1983 https://doi.org/10.1111/j.2164-0947.1983.tb02799.xCitations: 8 † This investigation was supported in part by Grant AM-08823 from the National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases of the National Institutes of Health. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume41, Issue1 Series IIAugust 1983Pages 173-182 RelatedInformation
Rats were given intraperitoneal injections of 2 mCi of carrier-free 32Pi and substances known to activate liver phenylalanine hydroxylase. After 30 min, these animals were anesthetized and their livers removed for analysis of enzyme activity, 32Pi incorporation into immunoprecipitated phenylalanine hydroxylase and [gamma-32P]ATP specific activity. Following glucagon treatment, rat liver phenylalanine hydroxylase activity was stimulated more than 6-fold when assayed in the presence of the natural cofactor, tetrahydrobiopterin (BH4). Glucagon injection also resulted in an incorporation of 0.41 mol of 32Pi/mol of hydroxylase subunit (approximately 50,000 Da). In vivo stimulation of phenylalanine hydroxylase activity and 32Pi incorporation by glucagon had been previously observed in this laboratory (Donlon, J., and Kaufman, S. (1978) J. Biol. Chem. 253, 6657-6659). However, we show for the first time in the present study that in vivo treatment with phenylalanine alone results in a 4-fold increase in the BH4-dependent activity of phenylalanine hydroxylase concomitant with a significant incorporation of phosphate into phenylalanine hydroxylase (0.51 mol of 32Pi/mol of hydroxylase subunit). It is further demonstrated in vivo that the combined treatment with phenylalanine and glucagon results in a greater than 10-fold stimulation of BH4-dependent activity and the greatest level of 32Pi incorporation (0.75 mol of 32Pi/mol of hydroxylase subunit). Phenylalanine did not produce an elevation in plasma glucagon in these animals. A model is, thereby, proposed with respect to the ligand binding effects of phenylalanine on the state of phosphorylation and activation of phenylalanine hydroxylase. The significance of these regulatory roles are considered in light of the probable physiological environment of the enzyme.
Transactions of the New York Academy of SciencesVolume 41, Issue 1 Series II p. 61-69 Stereoheterotopism and Prochirality H. HIRSCHMANN, H. HIRSCHMANN Department of Medicine Case Western Reserve University Cleveland, Ohio 44106 Address for correspondence: 14018 Becket Road, Shaker Heights, Ohio 44120.Search for more papers by this author H. HIRSCHMANN, H. HIRSCHMANN Department of Medicine Case Western Reserve University Cleveland, Ohio 44106 Address for correspondence: 14018 Becket Road, Shaker Heights, Ohio 44120.Search for more papers by this author First published: August 1983 https://doi.org/10.1111/j.2164-0947.1983.tb02785.xCitations: 5 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume41, Issue1 Series IIAugust 1983Pages 61-69 RelatedInformation
Transactions of the New York Academy of SciencesVolume 41, Issue 1 Series II p. 187-198 Characterization of Influenza Viral Transcriptional Complexes† OLGA M. ROCHOVANSKY, OLGA M. ROCHOVANSKY Department of Molecular Virology The Christ Hospital Institute of Medical Research Cincinnati, Ohio 45219Search for more papers by this author OLGA M. ROCHOVANSKY, OLGA M. ROCHOVANSKY Department of Molecular Virology The Christ Hospital Institute of Medical Research Cincinnati, Ohio 45219Search for more papers by this author First published: August 1983 https://doi.org/10.1111/j.2164-0947.1983.tb02801.x † This work was supported by Public Health Service Grant AI 14733 from the National Institute of Allergy and Infectious Diseases. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Volume41, Issue1 Series IIAugust 1983Pages 187-198 RelatedInformation
Transactions of the New York Academy of SciencesVolume 41, Issue 1 Series II p. 83-86 Regulation of Hexose Transport-Carrier Activity in Cultured Animal Fibroblasts: Another Confrontation with Cellular Recycling Requiring Oxidative Energy Generation? HERMAN M. KALCKAR, HERMAN M. KALCKAR Department of Chemistry Boston University College of Liberal Arts Boston, Massachusetts 02215Search for more papers by this author HERMAN M. KALCKAR, HERMAN M. KALCKAR Department of Chemistry Boston University College of Liberal Arts Boston, Massachusetts 02215Search for more papers by this author First published: August 1983 https://doi.org/10.1111/j.2164-0947.1983.tb02788.xCitations: 5AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume41, Issue1 Series IIAugust 1983Pages 83-86 RelatedInformation
Transactions of the New York Academy of SciencesVolume 41, Issue 1 Series II p. 237-242 Serotonin-Binding Protein: Function in Synaptic Vesicles† HADASSAH TAMIR, HADASSAH TAMIR Division of Neuroscience New York State Psychiatric Institute, and the Department of Psychiatry College of Physicians & Surgeons of Columbia University New York, New York 10032Search for more papers by this author HADASSAH TAMIR, HADASSAH TAMIR Division of Neuroscience New York State Psychiatric Institute, and the Department of Psychiatry College of Physicians & Surgeons of Columbia University New York, New York 10032Search for more papers by this author First published: August 1983 https://doi.org/10.1111/j.2164-0947.1983.tb02805.xCitations: 6 † This work was supported in part by Grant 09335 from the National Science Foundation. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume41, Issue1 Series IIAugust 1983Pages 237-242 RelatedInformation
Transactions of the New York Academy of SciencesVolume 41, Issue 1 Series II p. 97-102 Solving Problems That May Arise in Devising High-Sensitivity Pyridine Nucleotide Analytical Systems† OLIVER H. LOWRY, OLIVER H. LOWRY Department of Pharmacology Washington University School of Medicine St. Louis, Missouri 63110Search for more papers by this author OLIVER H. LOWRY, OLIVER H. LOWRY Department of Pharmacology Washington University School of Medicine St. Louis, Missouri 63110Search for more papers by this author First published: August 1983 https://doi.org/10.1111/j.2164-0947.1983.tb02790.x † This work was supported in part by Grant BC-4W from the American Cancer Society and by Grants NS-08862 and EY-02294 from the National Institutes of Health. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Volume41, Issue1 Series IIAugust 1983Pages 97-102 RelatedInformation
