The emergency resuscitation room serves as the site for initial assessment and resuscitation of critically ill patients. Most patients are transferred to specialized wards for further management after emergency intervention. Currently, prediction tools for mortality risk in this critically-ill population remain scarce. This study aimed to develop a nomogram model integrating early biomarkers to predict 30-day in-hospital mortality among patients hospitalized following emergency resuscitation room care. A single-center retrospective study was performed. A total of 986 adult critically ill patients transferred from the emergency resuscitation room to specialized wards at Zunyi First People’s Hospital between January 2023 and December 2025 were enrolled. Missing data were handled by multiple imputation (m = 5). Candidate predictors were screened by least absolute shrinkage and selection operator (LASSO) regression with dual-stability criteria (≥ 70
Rapid Sequence Intubation (RSI) is an advanced airway intervention performed by Emergency Care Practitioners (ECPs) in South Africa to secure a definitive airway for critically ill or injured patients in the out-of-hospital setting. Although RSI forms part of advanced out-of-hospital airway management practice in South Africa, limited evidence describes documented pharmacological practices, airway management strategies, procedural outcomes, and peri-intubation Adverse Events (AEs). This multicentre study described documented out-of-hospital RSI practices performed by ECPs in selected South African provinces. A descriptive cross-sectional retrospective record review was conducted using patient care records from participating public and private Emergency Medical Service (EMS) providers in Gauteng, KwaZulu-Natal, and the Western Cape provinces between January 2019 and April 2025. Patient care records documenting RSI performed by Health Professions Council of South Africa (HPCSA)-registered ECPs were reviewed using a predefined data extraction tool. Variables included patient characteristics, pharmacological agents administered, airway management practices, procedural outcomes, and documented AEs. Data were analysed using descriptive statistics, with exploratory analyses examining associations between selected pharmacological strategies and first-pass intubation success, and between multiple intubation attempts and documented AEs using Odds Ratios (ORs), 95
The Glasgow Coma Scale (GCS) measures level of consciousness. Its agreement with hospital diagnosis-based injury severity among patients identified by emergency medical services (EMS) as having suspected severe trauma remains uncertain. This population-based cohort study analyzed 6,179 patients aged ≥ 15 years with suspected severe trauma in South Korea (2022–2023), linking 119 EMS run-sheet records with National Emergency Department Information System data. Destination patterns were evaluated using two complementary severity definitions: prehospital GCS 3–8 as the primary classification and a provider-supplied binary indicator of International Classification of Diseases-based Injury Severity Score (ICISS)-2020 < 0.9 as a secondary diagnosis-based reference. Destination undertriage was quantified for each severity definition. Level 1–2 transport proportions were reported descriptively and separately for patients with GCS 13–15 and for patients with ICISS ≥ 0.9. Associations between each prehospital time interval and initial-hospital mortality were assessed in separate regression models adjusted for age, sex, and weighted Revised Trauma Score (RTS). Among 5,841 patients with complete data on both severity criteria, prehospital GCS-based classification and post-hospital ICISS-based severity showed weak positive concordance (Cohen’s κ = +0.192, 95
In-hospital cardiac arrest (IHCA) is associated with substantial mortality. We aimed to develop and internally validate a nomogram to predict IHCA after the 24-hour landmark among adult inpatients. This single-center retrospective case-control study included 216 IHCA cases and 649 randomly selected non-IHCA controls admitted from January 2020 to December 2024. All were alive and hospitalized at the 24-hour landmark; predictors were obtained during the first 24 h, and the outcome was subsequent IHCA before discharge. An 80:20 split yielded a training cohort (n = 692; 173 cases) and an internal validation cohort (n = 173; 43 cases). Missing data were handled using 20 imputed datasets, with imputation models fitted in the training cohort and applied to the validation cohort. We used least absolute shrinkage and selection operator (LASSO) logistic regression to screen 46 candidate predictors, followed by backward stepwise logistic regression. We assessed discrimination, calibration, Brier score, decision curve analysis, and bootstrap validation. We also conducted an exploratory comparison with the National Early Warning Score (NEWS), calculated from admission observations. The final model included hemoglobin, lactate, log-transformed N-terminal pro-B-type natriuretic peptide (NT-proBNP), fasting blood glucose, serum potassium, and creatine kinase-MB (CK-MB). The area under the receiver operating characteristic curve (AUC) was 0.801 (95
Extracorporeal cardiopulmonary resuscitation (ECPR) is a salvage therapy for refractory cardiac arrest (CA) in adults. However, its high cost, technical complexity, and prolonged support requirements necessitate critical evaluations of cost-effectiveness. This retrospective study enrolled 203 adult patients undergoing ECPR with hospitalization duration more than 24 h between January 2020 and December 2024. The incremental cost-effectiveness ratio (ICER) was calculated to compare in-hospital versus onsite ECPR, and shockable versus non-shockable rhythm groups. A stratified incremental cost-effectiveness evaluation was performed to examine the association between ECMO support duration and early survival outcomes. The discharge survival rate was 30.05
