Non-invasive monitoring of cellular adhesion and behavior is essential for lab on chip systems, yet current electrical and optical approaches require external stimuli or labels. Here we introduce two-dimensional adhesion...
A geometry-driven 3-D printed microfluidic platform integrates rapid, enzyme-free dechorionation, chorion filtration, and cell dissociation while preserving cell viability and enabling backflush-assisted device reuse.
Existing three-dimensional (3D) skin equivalents are limited by long maturation times, incomplete dermal architecture, and poor compatibility with systemic assays. We develop a microfluidic full-thickness skin model using a decellularized...
We present a biomimetic microfluidic device that experimentally decouples three static and dynamic determinants governing flow in the small intestine: villus-like structures, channel height, and dynamic wall deformation associated with...
Ultrahigh throughput screening of an enzyme library provides a dense dataset to train a generative machine learning model. Novel enzymes designed by this model can outperform the best enzymes in the screened library.
