Bow Hunter syndrome (BHS) is a rare cause of pediatric vertebral artery dissection (VAD) and posterior circulation arterial ischemic stroke (AIS) due to dynamic compression during head rotation. Imaging features, vascular evolution, and outcomes remain poorly defined. We reviewed children with definite or probable BHS diagnosed at a tertiary pediatric center between 2010 and 2026. A systematic review identified published pediatric cases (0–18 years) of definite/probable BHS. Twelve boys were included (mean age, 7.3 years; mean follow-up, 54.4 months). Posterior circulation AIS occurred in 10/12 (83.3
Hereditary hemorrhagic telangiectasia (HHT) is an inherited vascular disorder characterized by telangiectasias and arteriovenous malformations (AVMs) in multiple organs. Although brain MRI screening is recommended in all patients with HHT, in many centers, this may be difficult to implement due to organizational constraints. The aim of this study was to develop a machine learning model to predict the presence of bAVMs and other cerebrovascular malformations in patients with HHT, with the goal of supporting risk stratification in centers where genotype information is already available and identifying patients who may benefit from closer and more conservative surveillance. All patients with confirmed diagnosis of HHT, complete genetic work-up, and radiological screening (2018–2026) were included for the analysis. Two end points were defined: probability of detecting bAVMs, and probability of detecting any cerebrovascular findings. Analysis was performed using Python and R. A total of 142 patients with confirmed HHT (meeting ≥ 3 Curaçao criteria) were included. For bAVM prediction, both models showed good discrimination, with an AUC of 0.84 (95
To characterize the neuroimaging spectrum of nevoid basal cell carcinoma syndrome (NBCCS), with particular emphasis on cerebellar abnormalities. We retrospectively evaluated cranial computed tomography and magnetic resonance imaging examinations of patients with clinically and/or genetically confirmed NBCCS followed at a tertiary center between 2008 and 2023. Studies were independently reviewed by an experienced neuroradiologist and a radiology resident. Dural calcifications, odontogenic keratocysts, intracranial tumors, cerebellar morphology, and other structural abnormalities were assessed together with clinical and genetic findings. Seventeen patients (10 males and 7 females; age range, 1–70 years) were included. Dural calcification was detected in 13 of 16 evaluable patients (81.3
To investigate the association between endovascular treatment strategy and the occurrence of postprocedural DWI lesions and periprocedural complications as well as retreatment rates in patients undergoing elective endovascular treatment (EVT) for unruptured wide-neck intracranial aneurysms. This retrospective single-center study includes all consecutive patients who underwent elective EVT with stent-assisted coiling (SAC) or Contour device (CD) of unruptured wide-neck intracranial aneurysms between January 2019 and January 2026. Wide-neck aneurysms were defined as aneurysms with a neck ≥4 mm and/or a dome-to-neck ratio < 2. Postprocedural MRI was assessed for new DWI lesions. Uni- and multivariable regression analysis was performed to identify predictors for the primary outcome variables DWI lesions and periprocedural complications. Secondary outcome variables included procedure time, residual perfusion and retreatment rates. A total of 96 patients (50
There is no consensus on antiplatelet management after flow-diverter (FD) deployment. While prolonged dual antiplatelet therapy (DAPT) remains common, this approach carries haemorrhagic risks. We evaluated the safety of a short, location-tailored DAPT protocol for patients treated with FDs for intracranial aneurysms. We retrospectively reviewed consecutive patients undergoing elective FD treatment for intracranial aneurysms in our department. Patients followed a post-procedural DAPT protocol tailored to target vessel location: 1-month DAPT for internal carotid (ICA) and vertebral arteries (VA), and 3-month for other locations, followed by single antiplatelet therapy (SAPT). Periprocedural and delayed thromboembolic and haemorrhagic complications were assessed. Seventy-five patients with 82 aneurysms were included. Median DAPT duration was 43.0 days (IQR: 34.0–92.0) for ICA/VA, and 93.5 days (IQR: 90.7–99.0) for other locations. Periprocedural symptomatic neurological thromboembolic complications occurred in 1/82 (1.2
