Objective The first objective was to investigate the association between cognitive performance and disease-related factors in fibromyalgia (FM). The second objective was to compare non-cognitive impairment group with mild cognitive impairment group in FM. Material and methods Forty-nine FM female participants were included. Individuals with FM were divided into two groups. Scores of 23 or higher were defined as non-cognitive impairment group, and scores below 23 were defined as mild cognitive impairment group. The non-cognitive impairment group had 20 FM, and the mild cognitive impairment group had 29 FM. Body mass index, Montreal Cognitive Assessment (MoCA) Test, Fibromyalgia Impact Questionnaire (FIQ), Widespread Pain Index (WPI), Symptom Severity Scale (SSS), Multidimensional Assessment of Fatigue (MAF), Beck Anxiety Inventory (BAI), Pittsburgh Sleep Quality Index (PSQI), Biopsychosocial Questionnaire (BETY-BQ), Short Form-36 (SF-36), Timed Up and Go Test (TUG), and dual-task performance were assessed. Results MoCA had low-level correlation with WPI (r: −0.424; p: 0.003), SSS (r: −0.319; p: 0.031), BAI (r: −0.316; p: 0.028), BETY-BQ (r: −0.345; p: 0.016), TUG (r: −0.379; p: 0.012), and dual-task performance (r: −0.294; p: 0.045). The intergroup comparison revealed a difference in favor of non-cognitive impairment group in BETY-BQ (p: 0.033). In multiple regression analysis, the greatest contribution to the model of MoCA came from WPI (Beta: −0.395; p: 0.005). The model explains approximately 15.6% of the variance in the dependent variable (MoCA). Conclusion Cognitive performance of FM might be associated with pain, symptom severity, anxiety, biopsychosocial condition, mobility, and dual-task performance. Cognitive status could make a difference in biopsychosocial condition. Widespread pain made the greatest contribution for cognitive performance.
Introduction Low back pain (LBP) is a leading global cause of disability with major functional and socioeconomic consequences. Objective This study aimed to describe the epidemiology, risk factors, disability burden, and perceptual awareness of LBP in patients attending tertiary university hospitals. Methods In this cross-sectional study, 1047 adults with LBP were recruited from tertiary-care university hospitals. Demographic, clinical, and occupational data were collected. Disability was assessed using the Oswestry Disability Index (ODI), and perceptual awareness with the Fremantle Back Awareness Questionnaire (BAQ). Results The cohort had a mean age of 42.1 years with female-to-male ratio 1.3:1. The mean ODI was 34.3 and mean BAQ was 8.7. Males reported higher disability, while females showed higher BAQ scores. Work absence was longer in males (6.1 vs. 3.3 weeks; p=0.003). Smokers had higher ODI scores (p=0.001), and obesity was associated with higher BAQ scores (p<0.0001). Patients with non-specific LBP (n=218) reported lower ODI compared to those with defined diagnoses (p<0.0001). BAQ correlated significantly with ODI and BMI (both p<0.0001). Conclusion LBP-related disability and perceptual awareness are shaped by demographic, lifestyle, and clinical factors. Work absence remains a significant burden, and non-specific LBP is highly prevalent. These findings underscore the importance of interventions that address both physical and perceptual dimensions of LBP.
Introducción La miositis eosinofílica idiopática (MEI) es una miopatía inflamatoria poco comprendida. Se presenta el caso de una paciente con esta condición, quien logró una resolución completa de sus síntomas con el tratamiento instaurado. Presentación caso Mujer de 26 años que indicó cambios inflamatorios y dolor en el antebrazo derecho por un periodo de 30 días. Al examen físico se observó tenosinovitis de los flexores de la mano derecha; los paraclínicos mostraron eosinofilia y elevación de IgE, la resonancia magnética evidenció signos de miositis en el músculo pronador cuadrado y los flexores profundos de los dedos, así como tenosinovitis distal del antebrazo, y la biopsia mostró infiltrado inflamatorio linfoplasmocitario con abundantes eosinófilos de localización endomisial y perimisial. Se inició deflazacort y antihistamínicos, logrando una resolución completa de la sintomatología. Conclusiones La MEI es una enfermedad rara, con manifestaciones clínicas heterogéneas. Se espera que este reporte contribuya a una mejor comprensión de esta condición y sirva como base para futuros estudios relacionados con la MEI.
The clinical relevance of skin ultrasound evaluation in systemic sclerosis (SSc) and psoriasis (PsO) is significant, as it provides a non-invasive, objective, and reproducible method for assessing skin involvement, which is crucial for diagnosis, monitoring disease progression, and evaluating treatment efficacy. High-frequency ultrasound (HFUS) and shear wave elastography (SWE) are particularly useful in quantifying skin thickness and stiffness, parameters that correlate with disease activity and severity. This approach offers a more sensitive alternative to traditional methods such as the modified Rodnan skin score (mRSS), which can be subjective and variable. This article details the specific clinical applications and benefits of skin ultrasound (US) in SSc and PsO. Although the reviewed studies primarily focus on SSc, the principles of using US for skin evaluation can be extended to PsO. In PsO, US can help assess the extent of skin involvement, monitor treatment response, and potentially differentiate between active and inactive lesions, although specific studies on PsO were not detailed in the analyzed contexts. In contrast to advancements in SSc, the application of skin US in PsO requires further exploration to establish standardized protocols and validate its clinical utility. The potential of US to provide detailed insights into PsO-related skin pathology remains promising, warranting further research to fully understand its benefits. This document presents different US techniques, imaging windows, and technical aspects of performing skin US in SSc and PsO with skin involvement, covering the advantages and limitations of each method in both diseases.
Introducción Las vasculitis de grandes vasos son enfermedades inflamatorias crónicas que afectan las arterias de gran calibre y pueden generar complicaciones graves, como isquemia y aneurismas. En Colombia, la variabilidad en la aplicación de guías y en el acceso al tratamiento resalta la necesidad de una guía de práctica clínica adaptada al contexto nacional. Objetivo Formular recomendaciones basadas en la mejor evidencia disponible, para el diagnóstico, tratamiento y seguimiento de las vasculitis de grandes vasos en Colombia. Materiales y métodos Se conformó un grupo multidisciplinario de expertos y se aplicó la metodología Grading of Recommendations, Assessment, Development and Evaluation (GRADE) para garantizar la solidez de las recomendaciones. Se realizaron revisiones sistemáticas y se formularon recomendaciones adaptadas al contexto colombiano, en las cuales se consideró eficacia, seguridad, costos y equidad. Resultados Se formularon recomendaciones para el manejo de pacientes con arteritis de células gigantes (ACG) y arteritis de Takayasu (ATK). La guía incluye orientaciones sobre el uso de glucocorticoides, inmunosupresores convencionales, medicamentos biológicos y otras opciones terapéuticas, así como consideraciones para el abordaje quirúrgico y el seguimiento. Se enfatiza la importancia de una toma de decisiones individualizada, basada en la actividad y gravedad de la enfermedad, los factores de riesgo asociados, las preferencias del paciente y la disponibilidad de las intervenciones. Conclusiones Esta guía de práctica clínica proporciona recomendaciones para optimizar el tratamiento y seguimiento de pacientes con vasculitis de grandes vasos en Colombia, con el fin de reducir la variabilidad en la atención, mejorar los desenlaces clínicos y apoyar la toma de decisiones informadas en el manejo de estos pacientes.
