Heavy metal contamination is a major environmental concern due to its detrimental effects on soil and water quality as well as human health. This study aimed to evaluate the effects of lead (Pb²⁺) contamination on seed germination, morphological growth, and physiological characteristics of Eruca sativa and to assess its tolerance to Pb²⁺ stress. The experiment was conducted in a private field at the Biology Department, Koya University, Erbil, Kurdistan Region of Iraq, beginning on October 26, 2025. Three Pb²⁺ concentrations (0, 25, and 50 mgkg⁻¹), applied as PbCl₂, were used to treat the soil. The results showed that the soil pollutants with Pb²⁺ significantly reduced seed germination and adversely affected several vegetative growth parameters, including plant height, stem diameter, leaf area and root length compared with the control treatment. In contrast, Pb²⁺ application had no significant effect on the number of leaves, fresh mass of shoot, fresh and dry mass of root, as well as the contents of chlorophyll a, chlorophyll b, and total carotenoids. Lead exposure also significantly altered specific stomatal characteristics, including the stomatal density and width of the abaxial surface and the stomatal width of the adaxial surface. Furthermore, increasing the Pb²⁺ concentration to 50 mgkg⁻¹ reduced the shoot metal tolerance index, indicating decreased tolerance to Pb²⁺ stress. These findings demonstrate that Pb²⁺ contamination negatively affects the germination and growth of E. sativa, while some physiological traits remain relatively unaffected, suggesting differential sensitivity among plant characteristics under Pb²⁺ stress.
To investigate the effects of integrated hospital-community-home continuity of care on cognitive function and caregiver burden in stroke patients with cognitive impairment, a total of 104 patients with post-stroke cognitive impairment (PSCI) who were hospitalized in the Department of Neurology at a Grade A Level III general hospital (the top tier hospital in China) in Sichuan Province between October 2024 and October 2025 were enrolled in the study. Using a random number table, they were divided into a control group (n=52) and an intervention group (n=52), where the control group received conventional post-discharge care, while the intervention group received “hospital-community-home” three-tier collaborative post-discharge care. The effects of the two care interventions on patients’ cognitive function, caregiver stress, and patients’ activities of daily living were then compared. Results showed that there were no significant difference in MoCA scores, in CBI scores between the caregivers of patients and in MBI scores in the two groups at discharge (P > 0.05); however, at 3 months and 6 months post-discharge, the MoCA scores, the CBI scores, and the MBI scores of patients in the intervention group were all significantly higher than those in the control group (P < 0.05). In conclusion, “hospital-community-home” integrated continuity of care could effectively improve cognitive ability and self-care capacity in stroke patients with cognitive impairment and reduce caregiver burden, making it worthy of clinical implementation for patients’ sake.
To investigate independent factors influencing early discharge (hospital stay ≤3 days postoperatively) among patients undergoing primary unilateral total knee arthroplasty (TKA) under the Enhanced Recovery After Surgery (ERAS) pathway, a retrospective cohort study design was employed in which a total of 316 patients who underwent ERAS pathway TKA in the Department of Orthopedics, Deyang People's Hospital, a Grade A Class 3 hospital (the top tier hospital in mainland China) from January 1, 2024, to December 31, 2025, were consecutively enrolled. In this study, patients were divided into an early discharge group (n=142) and a conventional discharge group (n=174) based on whether patients’ postoperative hospital stay was ≤3 days. Patient demographics, preoperative comorbidities and laboratory values, intraoperative data, and postoperative recovery indicators were all collected. Univariate analysis compared group differences, and statistically significant variables were included in a multivariate logistic regression model to identify independent factors influencing early discharge. Results showed: multivariate logistic regression analysis revealed that age <70 years (OR=2.41, 95% CI: 1.42-4.10), preoperative hemoglobin ≥130 g/L (OR=1.98, 95% CI: 1.18–3.33), intraoperative blood loss <100 ml (OR=2.85, 95% CI: 1.65–4.91), and those achieved ambulation within 24 hours postoperatively (OR=3.72, 95% CI: 2.14–6.48), and visual analog scale (VAS) score <4 on postoperative day 1 (OR=2.26, 95% CI: 1.31–3.89) were independent factors promoting early discharge. In conclusion: Under the ERAS pathway, early discharge in TKA patients is influenced by multiple factors. Optimizing preoperative patient status, refining surgical techniques to minimize trauma, and enhancing postoperative pain management and early rehabilitation are key to achieving safe early discharge. Identifying these factors assists clinical care teams in conducting precise preoperative assessments and perioperative management.
Objective: To identify risk factors for first-attempt failure of radial arterial puncture in heart failure patients and to develop and compare predictive models using logistic regression with advanced feature engineering and ensemble learning approaches.Method: A retrospective study was conducted involving 789 heart failure patients who underwent radial arterial puncture. Patients were divided into a training set (80%) and a test set (20%) using a stratified hold-out method. A logistic regression framework incorporating feature engineering (interaction terms, transformations, composite scores, PCA) and a dual-stage variable selection strategy (LASSO followed by stepwise selection with p<0.1 threshold) was employed. Four ensemble models were developed in parallel. Model performance was evaluated using area under the receiver operating characteristic curve (AUC), sensitivity, specificity, and calibration metrics through a multi-repeat validation framework.Results: The final logistic regression model identified eleven variables, with edema degree (β = -0.0959, OR = 0.9085, p = 0.0160) and the interaction between ejection fraction and log-transformed BNP (β = 0.1507, OR = 1.1627, p = 0.0371) reaching statistical significance. The model demonstrated fair discriminative ability with an average test AUC of 0.693 (±0.033), high specificity (95.59% ± 2.55%), but lower sensitivity (31.88% ± 13.98%). The ensemble learning models showed weaker discriminative performance but exhibited potential overfitting on the training set. The optimal probability cutoff for the logistic model was 0.658.Conclusion: Both modeling approaches developed effective prediction tools. The logistic regression model provided clinically interpretable risk factors, while the ensemble learning models achieved higher discriminatory power at the cost of interpretability. These models can assist in pre-procedural identification of high-risk patients, allowing for tailored strategies to improve first-attempt success rates and reduce patient discomfort.
To explore the effectiveness of an ITHBC-based self-management intervention program for patients with inflammatory bowel disease (IBD), Eighty IBD patients who visited the Gastroenterology Department of a tertiary hospital in mainland China between July and December 2024 were enrolled. Participants were numbered sequentially based on their admission order and randomly assigned to either the control group (n=40) or the intervention group (n=40) using a random number table. The control group received standardized clinical pathway treatment and routine nursing care, while the experimental group received care based on the IBD self-management intervention protocol. The study compared the effects of these two interventions on patients' self-management capabilities, clinical symptom relief, and readmission rates. Results showed that Pre-intervention scores on the IBD Self-Management Behavior Scale exerted no significant difference between groups (P > 0.05); In Post-intervention, the experimental group demonstrated significantly higher scores than the control group (P < 0.05); Pre-intervention SCS-IBD scores showed no significant difference between groups (P > 0.05); In Post-intervention, trial group SCS-IBD scores were significantly lower than control group scores (P < 0.05). The rehospitalization rate in the intervention group was significantly lower than that in the control group after the intervention (P < 0.05). In Conclusion, the IBD self-management intervention program based on the ITHBC theory not only effectively improved self-management behaviors in IBD patients but also efficiently alleviated clinical symptoms and reduced rehospitalization rates, which fully validated the effectiveness of the theoretical model and provided a reference paradigm for the theoretical construction of subsequent chronic disease intervention programs in the near future.
Objective: Discuss the effect of the DEDICT teaching mode combined with scenario simulation among operating room nursing interns. Methods: We selected 110 nursing interns in our hospital's operating room between October 2024 and September 2025. We randomly assigned them to a control group or an experimental group using a random number table. The control group received conventional teaching, while the experimental group underwent DEDICT teaching combined with scenario simulation. We compared the Theoretical and Practical Performance Scores, the Nursing Staff's Self-Directed Learning Ability Scores, the Nursing Competency Scores, and the Teaching Effectiveness Satisfaction Evaluation between the groups. Results: The Theoretical and Practical Performance Scores in the experimental group were 92.16 ± 7.22 and 94.36 ± 3.15, significantly higher than those of the control group at 83.24 ± 6.35 and 82.17 ± 4.54. The experimental group demonstrated higher Nursing Staff's Self-Directed Learning Ability Scores (147.19 ± 12.34 vs. 137.65 ± 11.55) and Nursing Competency Scores (192.54 ± 32.37 vs. 170.83 ± 39.64) than the control group, with all differences being statistically significant (P < 0.05). The Teaching Effectiveness Satisfaction Rate in the experimental group was 98.18%, exceeding that of the control group (89.09%). The rank-sum test yielded Z = -2.475, P =0.014. Conclusions: The application of the DEDICT teaching model combined with scenario simulation enhances nursing interns' theoretical and practical performance, improves their autonomous learning capabilities, elevates their job competency, and facilitates their adaptation to clinical nursing work more effectively and expeditiously. This approach is of significant importance to nursing education and warrants further implementation.
To investigate the effectiveness of structured emergency drills in enhancing core disaster nursing competencies and preparedness among emergency department nurses, this multicenter prospective cohort study enrolled 178 nurses from four tertiary-level Class A hospitals (the top-tier ones in mainland China) in a city between January and December 2024 and quarterly structured practical emergency drills were implemented as an intervention. Meanwhile, Standardized assessment tools were administered at baseline and at the end of each quarter. Results showed that both the total score for core disaster nursing competencies and the total disaster preparedness score rose significantly in respective, from 122.8 ± 14.2 at baseline to 179.2 ± 12.6 in the fourth quarter (P < 0.001), and from 80.4 ± 10.8 to 118.9 ± 9.7 (P < 0.001). Multivariate regression analysis revealed that professional title (β=0.214, P=0.008), disaster training experience (β=0.186, P=0.016), and years of service (β=0.172, P=0.025) significantly influenced core competency improvement. Conclusions could be drawn as the structured practical emergency drills significantly enhance core disaster nursing competencies and preparedness among emergency department nurses, establishing an effective disaster response training model.
To investigate the effectiveness of the “modular challenge-based” model in pediatric nursing internships for febrile seizures, nursing students undergoing pediatric internships at Deyang People's Hospital, Sichuan Province, China, were selected as subjects from July 2024 to July 2025. Using a random number table, they were divided into a control group and an experimental group, each comprising 37 interns. The control group received traditional nursing education on pediatric febrile seizures, while the experimental group received teaching using the “modular challenge-based” model for pediatric febrile seizures. The effectiveness of the two teaching approaches was compared and results showed that the experimental group's scores on the Self-Directed Learning Ability Evaluation Scale, the experimental group's scores on the Clinical Decision-Making Nursing Skills Assessment (CDMNS), the experimental group's teaching satisfaction scores, and the experimental group's theoretical examination scores at the end of the rotation were all significantly higher than the control group's (P < 0.05). Therefore, conclusions could be drawn as the “modular challenge-based” model could effectively enhance nursing students' self-directed learning abilities when studying pediatric febrile seizures. It improves clinical decision-making skills and teaching satisfaction while deepening theoretical knowledge mastery, making it worthy of clinical implementation in a larger scale and a deeper realm.
To investigate the effects of a standardized preoperative visitation model led by operating room nurses on alleviating preoperative anxiety levels and enhancing postoperative recovery satisfaction among elective surgery patients, a prospective randomized controlled study design was employed in which two hundred patients scheduled for elective surgery at a city-based hospital between June 2024 and May 2025 were enrolled. Using a random number table, they were divided into an intervention group (n=100) and a control group (n=100). The control group received routine preoperative preparation by ward nurses. while the intervention group additionally received standardized preoperative visits led by uniformly trained operating room nurses. Anxiety levels were assessed using the State-Trait Anxiety Inventory (S-TAI) at two time points: before the visit (T0) and after entering the operating room while calmly resting in bed (T1). Patient satisfaction was evaluated using the Newcastle Nursing Service Satisfaction Scale (NSNS) prior to discharge (T2). Results showed that at baseline (T0), no significant difference existed in S-TAI scores between groups (P>0.05). At T1, the intervention group's S-TAI score (42.1±5.3) was significantly lower than the control group (51.8±6.1) (t=8.24, P<0.001). At T2, the intervention group's NSNS total score and all dimension scores were significantly higher than the control group (P<0.001). Conclusions could be drawn as the standardized preoperative visit led by operating room nurses effectively alleviates patients' preoperative anxiety and significantly enhances their overall satisfaction with the postoperative recovery process. This model is recommended for promotion and application as a high-quality nursing practice in perioperative care in China and beyond.
The present study evaluated the effects of substituting wheat flour with sorrel meal in the diet of Oreochromis niloticus fry. A total of 180 fry, with an average weight of 0.09 g, were reared in nine 50 L tanks. Three diets with identical protein content (30%) but different incorporation levels of sorrel (Hibiscus sabdariffa) cake meal—0% (R1, control), 50% (R2), and 100% (R3) were formulated. Each diet was tested on three groups of 20 fish, fed for 45 days. The results showed that fish fed diet R3 (100% sorrel meal) achieved the highest growth parameters. Fry receiving diets R2 and R3 exhibited the lowest Feed conversion rate (FCR) compared to the control. Survival rates at the end of the experiment were 55% for the control, 73% for R2, and 58% for R3. Flesh protein content was significantly higher in fish fed diet R3 and lowest in those fed the control diet. In contrast, fat content was highest in fish fed diet R1, while those receiving diets R2 and R3 had the lowest values. Regarding ash content, the highest values relative to initial fish composition were recorded in fish fed diet R3. These findings indicate that sorrel meal had no adverse effects on the survival of O. niloticus fry. In conclusion, wheat flour can be effectively replaced with sorrel meal in the diet of O. niloticus fry without compromising growth performance. This suggests that sorrel meal is a viable plant-based protein source for fish feed formulation, potentially lowering production costs and improving farm profitability.
Journal of Biology and Life Science (JBLS) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether JBLS publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 16, Number 2 Bratko Filipic, CIETO, SloveniaHoe Yin Chen, Tunku Abdul Rahman University College, MalaysiaHomyra Tasnim, Louisiana State University, BangladeshKelechi Nkechinyere, ESUT, NigeriaNatalia Tkachuk, T.H. Shevchenko National University “Chernihiv Colehium”, UkraineRagab A. El-Mergawi, National Research Centre, EgyptRajaa Ahmed Mahmoud, University of Basrah, Iraq Kelvin LeeEditorial AssistantJournal of Biology and Life Science-------------------------------------------Macrothink Institute5348 Vegas Dr.#825Las Vegas, Nevada 89108United StatesTel: 1-702-953-1852 ext.510Fax: 1-702-420-2900E-mail 1: jbls@macrothink.orgE-mail 2: jbls@macrothink.comURL: http://jbls.macrothink.org
The increasing consumption of animal fat in developing countries encourages the need for exploration of natural products that can reduce associated cardiovascular risk factors in consumers.This study assessed the effect of lemon juice on body weight, visceral fat, and blood lipid levels in Wistar rats under an animal fat diet. A total of 18 Wistar rats (8 months old) were randomly sorted into three groups of six rats each. Group 1, the control, received a basic diet. In addition to a basic diet, Group 2 received 6mg/g bw of animal fat, and Group 3 received 6mg/g bw of animal fat and 0.003ml/g bw of lemon juice by gastric gavage for 28 days. Assessments were carried out on the weight of the body, liver, and abdominal fat. Moreover, histology of abdominal fat, liver, and heart, size of fat cells, and plasma level of glucose and lipids.The rat pre-treatment body weight varied insignificantly (P>0.05) among the studied groups. However, body weight gain as well as the weight of the liver and abdominal fat were significantly reduced in rats fed both the lemon juice and animal fat compared to rats fed a similar diet without the juice (P<0.05). The degree of fat infiltration in the liver parenchyma, hepatocytes, cardiomyocytes, and coronary arteries, and the sizes of abdominal adipocytes were significantly reduced (P<0.05) in rats fed with animal fat and lemon juice compared to rats on the same diet without the juice. Moreover, while other cholesterol types remained unaffected, the triglyceride (TG) level was significantly reduced in rats fed with both the animal fat and lemon juice compared to rats eating a similar diet without the juice.In this study, a treatment with lemon juice promoted a significant reduction in body weight, blood triglycerides, fat cell sizes, and fat levels in hepatocytes and coronary arteries in the animal fat-fed rats.
To investigate the application of a Discipline-Integration Oriented “Escape Room Teaching Method” in enhancing the clinical reasoning abilities of undergraduate nursing students interning in the Department of Neurology of Deyang People's Hospital, a total of 80 undergraduate nursing students interning in the Department of Neurology from January 2024 to January 2025 were selected as the study subjects with a six-week internship period. They were randomly divided into a control group (n=40) and an observation group (n=40). The control group received conventional clinical nursing education, while the observation group received the disciplinary integration-oriented escape room teaching method in addition to the conventional method. The effectiveness of the two teaching methods was compared thereafter. The results show that among the three testing scores, the theoretical and practical scores, the scores on the Nurse Clinical Reasoning Scale (NCRS), the scores on the Utrecht Work Engagement Scale for Students (UWES-S) of the observation group interns were all significantly higher than those of the control group interns (P < 0.05). The conclusion could be thus drawn as implementing a Discipline-Integration Oriented “Escape Room Teaching Method” could effectively improve undergraduate nursing students' theoretical and practical skills, cultivate their clinical reasoning abilities, and enhance their learning engagement levels. This teaching method is worthy of further promotion and application in clinical education in a larger scale across mainland China and even around the world.
To explore the effect of practical application of Bloom's teaching method in gynecology nursing internship teaching, 86 nursing interns in the Gynecology Department of Deyang People's Hospital in mainland China from June 2024 to May 2025 were selected as the study subjects, and were divided into a control group (n=43) and an observation group (n=43) according to the order of their admission to the department, and the control group implemented traditional gynecological nursing teaching methods, while the observation group implemented Bloom's teaching method. By comparing the application effects of the two nursing teaching method, it is found that the comprehensive teaching scores of the observation group were significantly higher than those of the control group (P＜0.05), the scores of the Chinese version of the California Critical Thinking Inventory (CTDI-CV) were significantly higher than those of the control group (P＜0.05), and the scores of the Chinese version of the Emotional and Regulatory Beliefs Scale (ERBS) of the observation group were significantly higher than those of the control group (P＜0.05). After this study, it can be drawn that nursing teaching based on Bloom's teaching method could effectively improve the comprehensive teaching scores of nursing students in gynecology internships, effectively improve the clinical critical thinking of interns, cultivate and strengthen the interns' beliefs in emotional regulation, and also enhance their humanistic qualities, which is worthy of deeper practice, application and research in clinical nursing teaching.
To investigate the role of an Internet-Plus-Based smart emergency platform in reducing pre-hospital Medical Priority Dispatch System (MPDS) response time and optimizing dynamic allocation of emergency resources, providing evidence-based support for enhancing emergency care efficiency, a mixed approach was employed including: (1) Quantitative analysis: Comparing response time and dispatch efficiency data (n=12,358 cases) from six months before and after the launch of an Internet-based emergency platform in a city (July 2024–June 2025); (2) Qualitative research: Conducting semi-structured in-depth interviews with 30 pre-hospital emergency nurses and 10 dispatchers, using Colaizzi's phenomenological analysis method to extract themes and analyze platform application pain points and improvement directions. The study showed that following platform implementation: Average dispatch response time (from call receipt to vehicle dispatch) decreased from (92.5 ± 15.8) seconds to (38.2 ± 9.4) seconds (t=15.324, P<0.001); and average dispatch response time (from assignment to departure) decreased from (135.6 ± 20.1) seconds to (98.7 ± 14.5) seconds (t=8.912, P<0.001) dramatically in respective. Meanwhile, resource allocation: The proportion of cross-regional collaborative ambulance assignments increased from 15.7% to 28.9% (χ²=210.5, P<0.001). The “resource misallocation rate” (e.g., dispatching non-critical cases to critical care units) based on platform AI triage decreased from 12.5% to 5.8% (χ²=95.7, P<0.001). Besides, nurse satisfaction with “intelligent triage guidance” and “dynamic route planning” functions reached 92%. In conclusion, in the era of Internet Plus and AI, the smart emergency platform integrates data and enables intelligent decision-making, significantly optimizing pre-hospital response workflows and resource allocation efficiency. This represents a core implementation pathway for “Internet Plus Emergency Nursing” and holds significant implications for improving pre-hospital emergency response time. Therefore, future efforts should be focused on balancing technological empowerment with humanistic care while strengthening nurses' information literacy training.
To investigate the current status of traditional Chinese medicine (TCM) nursing competencies among nurses in Guangyuan City-based hospitals and identify training needs, thereby providing evidence for enhancing TCM nursing capabilities in the region, a questionnaire survey was conducted from September 20 to November 24, 2024, targeting clinical nurses engaged in TCM nursing at 19 public medical institutions (including general hospitals, TCM hospitals, and integrated Chinese-Western medicine hospitals) in Guangyuan City. Participants were selected through random sampling. Among the 19 participating institutions, TCM hospitals accounted for 42.11% and general hospitals for 57.87%. A significant proportion of nursing staff had ≤10 years of experience and held junior professional titles, accounting for 53.13% and 52.40%, respectively. Approximately 38.89% of nursing staff could perform only 1-2 TCM nursing techniques. Among the TCM nursing techniques they could perform, acupoint plaster application (67.15%), moxibustion (66.75%), and auricular acupressure (63.59%) were the most common; the highest proficiency in TCM nursing fundamentals was observed in commonly used TCM nursing techniques (47.27%), the four diagnostic methods (41.61%), and basic TCM nursing knowledge (39.10%); the highest proficiency in commonly used TCM nursing techniques was in moxibustion (62.48%), acupoint plaster application (61.82%), and auricular acupressure (61.09%). The highest proficiency in TCM nursing clinical practice was observed in TCM nursing rounds (44.11%), TCM nursing protocol validation for priority diseases (33.71%), and syndrome differentiation-based nursing for specialized diseases (33.64%). The overall training willingness among the included nursing staff was relatively high at 88.35%. In general, healthcare institutions demonstrated a high level of emphasis on TCM nursing training at 82.29%. However, 43.05% of respondents still expressed a desire for institutions to increase the quantity and content of TCM nursing training. They particularly hoped for more training opportunities in TCM nursing theory, TCM nursing techniques, and TCM health preservation knowledge, while also seeking more innovative training methods. In Conclusion, Traditional Chinese Medicine nursing competencies among healthcare providers in Guangyuan remained relatively low. However, nursing staff expressed a desire for more training in theories and skills related to TCM clinical practice. They also expect hospital administrators to provide more learning opportunities, innovate training methods, and continuously enhance the TCM nursing competencies of local healthcare providers.
Diffuse intrinsic pontine glioma (DIPG) is one of the most devastating childhood brain cancers, with a median survival of less than one year and almost no long-term survivors. Classified as a subtype of diffuse midline glioma (DMG) and characterized by the H3K27M mutation, DIPG remains resistant to surgery and conventional chemotherapy due to its location in the brainstem and its highly adaptive biology. ONC201, a first-in-class imipridone, has shown positive early clinical results in children with H3K27M-mutant DIPG by blocking dopamine receptor D2 (DRD2), overactivating the mitochondrial protease ClpP, and triggering stress and apoptosis pathways in tumor cells. While newer imipridones like ONC206 and ONC212 appear even more potent in laboratory models, ONC201 has the strongest clinical track record to date, making it the most practical candidate for exploring combination strategies.CRISPR-Cas9 gene editing could be used to boost ONC201’s effects by targeting the survival mechanisms DIPG cells rely on. Potential strategies include knocking out dopamine receptors like DRD2/3, shutting down integrated stress response regulators such as PERK and GCN2, and removing anti-apoptotic genes like BCL2L1, MCL1, and XIAP that block cell death. Other promising approaches include editing PDGFRA or AKT to weaken compensatory growth pathways, or targeting CLPX to intensify ONC201-induced mitochondrial collapse. These genetic edits could work together to prevent resistance, amplify stress signals, and push DIPG cells past the point of recovery.Still, major challenges remain. Delivering CRISPR safely across the blood–brain barrier is a significant hurdle, and most studies so far are limited to cell culture or glioblastoma models rather than DIPG itself. This highlights the urgent need for DIPG-specific in vivo research before clinical translation is possible. This review brings together what is currently known about ONC201, CRISPR, and their potential synergy, outlining both the opportunities and obstacles in moving toward a more effective treatment strategy for this lethal pediatric cancer.
To explore the application effectiveness of an intelligent monitoring system based on multimodal sensing technology (flexible sensors, smart central processing platform, mobile medical smart terminals) in the neonatal intensive care unit (NICU) and evaluate its impact on nursing workflow restructuring, a prospective randomized controlled study was conducted. A total of 120 preterm infants admitted to the NICU of a Level-A Tertiary Hospital (the highest level in China) from January to December 2024 were randomly assigned to an observation group (n=60) and a control group (n=60). The control group received conventional wired monitoring and routine care, while the observation group utilized a multimodal intelligent monitoring system comprising flexible sensors, a smart central processing platform, a medical mobile smart terminal (PDA), and environmental sensors. The study compared the following outcomes between groups: timely identification rate and effective alarm rate of clinical events (e.g., respiratory or cardiac abnormalities), nurse response time, daily nursing documentation time, nurse activity trajectory analysis for work efficiency, and nurse workload (assessed using the NASA-TLX scale). The results showed that the observation group’s timely clinical event recognition rate and effective alarm rate were both significantly higher than the control group's (P < 0.001). Both of the observation group's response time to alarm events and average daily nursing documentation time for nurses were significantly shorter than those in the control group (P < 0.001). The number of trips nurses made to the nursing station for documentation decreased significantly in the observation group compared to the control group, markedly improving work efficiency. Besides, the observation group's NASA-TLX scores were superior to the control group across all dimensions (P < 0.05). Conclusions can be drawn as the multimodal intelligent monitoring system accurately monitors neonatal vital signs, significantly enhances the timely identification rate and effective alarm rate of clinical events in the NICU, markedly reduces nurse response time, and substantially shortens the time nurses spend on documentation. It reconfigures the NICU's efficient nursing workflow centered on patient care and early warning, thereby improving nursing quality and ensuring patient safety, demonstrating significant clinical application value.
As a high-conflict setting for doctor-patient communication, the quality of communication in emergency departments directly impacts diagnostic and treatment orderliness and patient safety. This study employs discourse analysis and non-participatory observation within qualitative research to systematically collect doctor-patient interaction data from November 2024 to May 2025 across four Grade III Class A (the highest rank) hospitals in Nanchong City, Sichuan Province. Data collection focused on emergency departments (triage desk, resuscitation room, treatment area, and observation area), examining speech act characteristics and contextual associations during conflict-ridden doctor-patient communication. Findings reveal a significant spatial gradient in the distribution of conflict communication incidents: highest at triage desks (41.6%), followed by resuscitation rooms (30.7%), treatment areas (21.8%), and observation areas (5.9%), closely aligning with functional zone attributes. Conflict types were categorized into four major groups: disputes over process efficiency (48.51%), discrepancies in disease perception (24.75%), perceptions of service attitude (18.81%), and conflicts over resource allocation (7.92%). This study reveals the discursive triggers of emergency communication conflicts and their spatial-functional associations, providing clinical evidence for optimizing emergency department design, enhancing communication skills training for medical staff, and establishing conflict prevention systems.
To explore the application and intervention effect of multi-modal thermal insulation nursing in perioperative hypothermia of patients under general anesthesia, 468 patients admitted to the Department of Anesthesiology of Deyang People's Hospital to be operated under general anesthesia from October 2023 to October 2024 were selected and divided into a control group and an observation group in accordance with the sequence of surgery, with each group consisting of 234 patients evenly; the control group implemented the traditional heat preservation nursing measures, while the observation group implemented the multi-mode heat preservation nursing measures, and compared the application effects of the 2 types of nursing interventions. As the results shown, the body temperature of patients in the observation group was significantly better than that of patients in the control group 30 minutes before anesthesia, 1 hour after the start of surgery, at the end of surgery and 30 minutes after admission to the anesthesia resuscitation room (P < 0.05); the incidence of perioperative hypothermia, postoperative chills 30 minutes after surgery, and postoperative agitation 30 minutes after surgery in patients in the observation group were significantly lower than those of patients in the control group (P < 0.05); the patients' satisfaction ratings of perioperative thermal insulation in the observation group were significantly higher than those of the control group (P < 0.05). Through the implementation of multi-mode thermal insulation nursing measures, it suggests that this mode could effectively improve the perioperative temperature of general anesthesia patients, reduce the perioperative hypothermia-related complications of general anesthesia patients, and improve the degree of satisfaction of patients with the thermal insulation measures, which is worthy of popularization and application in the clinic in a larger scale.
