Search result: Only two clinical studies concerning restorations were found.Clinical outcomes: The results indicate no difference in the survival rate after 12 and 24 months.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: There is a lack of clinical studies to this topic: Only three clinical trials were found and traced.Clinical outcomes: The results are conflicting or suggest no difference between conventional GIC and Compomers in regard to their anticariogenic effects.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: As the topic of CPP-ACP is of high-priority a more intensive systematic literature search was conducted in order to produce this evidence sheet. 22 clinical studies were found. In-situ studies, as well as studies including ACP/casein materials not covered by the Recaldent technology, as included in the original systematic review, were not includedClinical outcomes: Preventive effect: The results regarding the clinical efficacy of CPP-ACP in the prevention and treatment of dental caries, i.e. slowing the progress of early caries lesions/white spot lesions appears to be contradictive and no conclusive statement can yet be made based on the available evidence. The quality of the existing evidence requires further assessment. PLEASE NOTE: The outcome of the methodological quality assessment of trials may change the evidence-weight of the study conclusions.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: One clinical trial was found and traced concerning resin-modified GIC (RM-GIC). The material was Fuji II LC (compared to: Tetric Flow and Helioseal F). No trials were identified comparing conventional GIC (C-GIC) with composite resin.Clinical outcomes: The overall results suggest a higher antibacterial effect for RM-GIC up to 6 months.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: Only three clinical studies were found.Clinical outcomes: The results indicate no difference in the longevity between both types of materials.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: Twelve clinical trials were found and traced.Clinical outcomes: The overall results suggest no difference between RM-GIC and Compomers in regard to their anticariogenic effects.[‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: Only three clinical studies were found. Clinical outcomes: The results indicate no difference in the longevity between both types of materials. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: Nine clinical trials were found. Clinical outcomes: Minor or no improvements are reported when selective enamel etching was used. Selective enamel etching may not pose a hazard in terms of postoperative hypersensitivity. State of evidence and recommendations: The current level of clinical evidence to this topic is still limited in quantity and quality and more trials are needed in order to confirm these results. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result : Only trials with low-viscosity GIC were found. Clinical outcomes : The results suggest that cervical restorations placed with chemically cured GICs have good survival rates when compared to composite but are less aesthetic. State of evidence and recommendations : The quality of the existing evidence requires further assessment. ['Preliminary Systematic Literature Searches' are based on SYSTEM's periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result : No clinical evidence concerning adverse effects of aluminium, barium or strontium released from GICs were found. A review of the relevant laboratory literature, including a conservative calculation of any potential adverse clinical effect due to aluminium content, concludes that the amount of aluminum that could be leached into the body from glass-ionomer dental fillings is well below the permitted daily dose and almost certainly too small to have a measurable effect. This, in turn, suggests that there are unlikely to be any adverse health effects arising from the presence of these fillings.Clinical outcomes : NoneState of evidence and recommendations : The quality of the existing evidence requires further assessment.[u0027Preliminary Systematic Literature Searchesu0027 are based on SYSTEMu0027s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: One clinical trial was found. Clinical outcomes: There appears to be no difference in the success rate of both types.State of evidence and recommendations: The current level of clinical evidence to this topic appears to some extent contradictive and may still be limited in quantity and quality. Thus more trials are needed in order to confirm the current results.
Search result : 2 trials were found. Clinical outcomes : The results of the laboratory trials suggest that stannous ions have a remineralising (therapeutic) effect on dental tissue (particularly when stannous fluoride was compared to sodium fluoride). ['Preliminary Systematic Literature Searches' are based on SYSTEM's periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: Two prospective clinical controlled trials were found. Clinical outcomes: The results indicate that there may be a trend that coating can protect Fuji IX GP Extra against wear. State of evidence and recommendations: More clinical (prospective) randomised control trials (RCT) are needed. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: Three contradicting clinical trials were found so far. Clinical outcomes: Some results show that MI Paste Plus appears more effective in reducing white spot lesions than placebo and fluoride varnish after 3 months, while other results suggest that its effect appears to be equal to that of normal home care after 2 months. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: Two clinical trials were found. Clinical outcomes: There appears to be no difference in the survival rate of both types of restorations after 2 years. State of evidence and recommendations: The current level of clinical evidence to this topic appears to some extent contradictive and may still be limited in quantity and quality. Thus more trials are needed in order to confirm the current results.
Search result: Two clinical controlled trials were found. Clinical outcomes: The results suggest no difference in the failure rate of GIC restorations placed after either complete or incomplete removal of infected (soft) carious dentin. State of evidence and recommendations: The quality of the existing evidence requires further assessment. ['Preliminary Systematic Literature Searches' are based on SYSTEM's periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: Four clinical controlled trials were found between the period of 2004 and 2015 (19.11.15). Clinical outcomes: The results show that composite resin performs less satisfactory when compared to amalgam. State of evidence and recommendations: The quality of the existing evidence requires further assessment. ['Preliminary Systematic Literature Searches' are based on SYSTEM's periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: One article, reporting on 2 clinical trials, was identified, concerning plaque pH-decrease after sucrose challenge: (a) comparison of CPP-ACP containing paste with no paste; (b) comparison of CPP-ACP containing paste with placebo. Clinical outcomes: The results show a significant reduction in plaque pH fall after sucrose challenge with CPP-ACP containing paste. State of evidence and recommendations: The results of both reported trials need to be regarded with caution due to: unclear reporting of study methods and results in text and tables; spelling errors in text; use of a 'run-in phase' before the trial. A run-in phase is a stage before a trial where patients are pre-selected that respond well to treatment. Such stage effectively excludes patients, introduces potential selection bias and thus generates risk of overestimation of subsequent trial results. ['Preliminary Systematic Literature Searches' are based on SYSTEM's periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: Ten controlled clinical studies relevant to the topic were found. Clinical outcomes: The results indicate: - GIC/RM-GIC have higher caries-preventive effects than composite/amalgam in cases were no additional fluoride was provided to patients have been shown; - Topical fluoride is indicated as caries-preventive; - Mineral containing supplements, with and without casein appear to be at least as effective as topical fluoride in caries prevention; - The effect of chlorhexidine gel on caries prevention is unclear; - The use of an Intraoral fluoride-releasing system appears as effective s topical fluoride application. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
Search result: Twelve clinical trials were found and traced. Clinical outcomes: The overall results suggest no difference between RM-GIC and Compomers in regard to their anticariogenic effects. State of evidence and recommendations: The quality of the existing evidence requires further assessment. [‘Preliminary Systematic Literature Searches’ are based on SYSTEM’s periodic systematic searches of the dental literature and provide first overviews over existing clinical evidence but are limited in the number of databases searched, as well as the assessment of precision and internal validity of results and thus do not replace the need for a full systematic review report to the topic]
