Background/Objectives: Studies consistently demonstrate that microprocessor-controlled prosthetic knees (MPKs) improve mobility and quality of life for people with lower limb loss or absence by enhancing balance and reducing falls. However, the extent to which these benefits apply across demographic groups remains unclear. Therefore, we conducted a literature review to evaluate how representative and transferable research on MPKs is across different populations, and which factors influence this. Methods: Using systematic review principles and PRISMA guidelines, 27 studies were analysed from databases including Cochrane, CINAHL, MEDLINE, and PubMed, as of 20th September 2025. The included studies primarily focused on young-to-middle-aged adults, men, individuals with trauma-related amputation, and higher mobility levels. Results: We found that older adults, women, and individuals with amputation caused by vascular disease or diabetes were under-represented in MPK research. Moreover, variability in time since amputation complicates the generalisability of findings, as this factor significantly influences adaptation and functional outcomes. Conclusions: While evidence supports MPKs’ effectiveness in enhancing mobility and reducing the risk of falls, their benefits may not fully apply to under-represented groups, such as older adults, women, or low-activity users. Future research should prioritise more diverse participant samples to improve the generalisation of MPK outcomes across different demographics and functional levels.
Background/Objectives: Injection moulding has become a predictable technique for transferring a diagnostic wax-up to direct composite restorations. However, conventional workflows that rely exclusively on injectable flowable composites may have limitations in material handling, mechanical performance, and the dimensional stability of the transparent silicone index. The purpose of this technical note was to describe a silicone-guided modification of the injection moulding workflow, referred to as the compression moulding technique, and to illustrate its clinical application in three representative cases. Methods: The proposed workflow combines a dual-layer silicone index consisting of a transparent polyvinyl siloxane material supported by a high-hardness bite-registration silicone with a preheated medium-viscosity resin composite. Following digital planning and diagnostic wax-up, the composite is positioned within the silicone index and adapted to the prepared tooth surfaces by controlled compression. Three clinical cases with different restorative indications were included to demonstrate the technique’s versatility. Results: In all three cases, the proposed workflow enabled accurate transfer of the diagnostic wax-up while providing improved stabilization of the transparent silicone index during composite placement. The combination of controlled compression, a rigid supporting silicone, and preheated paste composite facilitated material adaptation, minimized manual sculpting, and produced predictable esthetic outcomes in a minimally invasive chairside procedure. Conclusions: The compression moulding technique represents a practical modification of the conventional injection moulding workflow for direct composite restorations. The proposed protocol may improve index stability, material handling, and clinical versatility while maintaining the advantages of silicone-guided restorative procedures. Because the present article is intended to describe a technical workflow supported by representative clinical cases, further prospective clinical studies with long-term follow-up are required before conclusions regarding clinical superiority or long-term performance can be drawn.
Background: Accurate reproduction of subgingival finish lines remains a major challenge in fixed prosthodontics. This scoping review aimed to map and synthesize current evidence comparing digital and conventional impression techniques for tooth-supported restorations with subgingival margins. Methods: The review followed the Arksey and O’Malley framework and was reported in accordance with PRISMA-ScR guidelines. Four electronic databases (PubMed, Scopus, Web of Science, and Google Scholar) were searched for English-language studies published between 2005 and 2025. Eligible studies included both in vitro and in vivo investigations evaluating impression techniques in subgingival conditions. Results: A total of 51 studies were included, of which 66.6% were in vitro. Digital scanning accuracy decreased consistently as subgingival depth increased, particularly beyond approximately 1 mm below the gingival margin. Conventional elastomeric impressions generally demonstrated more consistent reproduction of deeper subgingival margins. Conclusions: Impression accuracy in subgingival conditions appears to depend primarily on finish line depth and clinical conditions rather than on impression modality alone. Digital workflows appear reliable for equigingival and shallow subgingival margins, whereas conventional or hybrid approaches may remain advantageous in deeper subgingival scenarios. Further well-designed in vivo studies using standardized measurement protocols are needed to support evidence-based clinical recommendations.
Background/Objectives: To compare the effects of different surface treatments on the color and translucency of three types of zirconia ceramics. Methods: Ninety CAD/CAM-milled zirconia disks (10 mm diameter, 1 mm thickness) were fabricated from Cercon HT (3-YTZP), IPS e.max ZirCAD MT (4-YTZP), and Cercon XT (5-YTZP). Baseline CIE Lab* coordinates were measured using a digital spectrophotometer. The disks underwent one of three surface treatments: 50 µm alumina air-particle abrasion (AAA), Zircos-E etching (ZE), or 100 µm glass bead air-particle abrasion (GBA). Post-treatment CIE Lab* measurements were obtained, and color change (ΔE00, CIEDE2000) and translucency change (ΔTP00) were calculated. Results: Regarding color change (ΔE00), 50 µm AAA produced the greatest change, followed by ZE, while GBA caused the smallest change. Surface treatment and its interaction with material type were found to exert a significant effect, whereas material type alone was not significant. Cercon XT showed the highest numerical ΔE00 value among the materials, although the difference was not statistically significant. All ΔE00 values were below the clinical acceptability threshold (<1.8). No significant effects of surface treatment, material type, or their interaction were observed for translucency change (ΔTP00) after surface treatment. Baseline translucency values (TP00) differed significantly, with Cercon XT being the most translucent, followed by ZirCAD MT and Cercon HT, but these differences did not result in significant ΔTP00 changes post treatment. Conclusions: Surface treatments and their interaction with material type significantly affected zirconia color change, with 50 µm alumina air-particle abrasion producing the most pronounced effect. Material type alone did not significantly influence ΔE00, though Cercon XT showed the highest numerical value. Translucency change (ΔTP00) after treatment was unaffected by surface treatment or material–treatment interaction.
Background/Objectives: Lower-limb amputation significantly impacts autonomy and daily functioning. Microprocessor-controlled prosthetic knees (MPKs) improve mobility, safety, and quality of life compared with non-microprocessor prosthetic knees (nMPKs). Despite general benefits, differences among MPK models remain unclear. The goal of this investigation was to evaluate functional mobility and patient-reported outcomes in active transfemoral amputees using a new MPK (PROTEOR QUATTRO) compared with existing MPKs. Methods: In this multicenter cross-over clinical trial, active transfemoral amputees were assessed using patient-specific functional scales (PSFS), standardized locomotor capacity tests (6MWT, 10mWT, HAI, SAI) and satisfaction and quality-of-life questionnaires (PEQ-A, SF-36, ESAT). Biomechanical data collection was performed during walking test, to examine gait symmetry indices. Results: The QUATTRO MPK was associated with significantly higher PSFS scores, reflecting higher self-rated ability in performing chosen daily life activities compared with patient’s current prosthesis. Standardized locomotor tests revealed comparable performance between devices. Biomechanical analyses showed similar symmetry indices for QUATTRO and other MPKs. Patient-reported outcomes showed an improvement in physical health with QUATTRO, while overall satisfaction remained similar. Conclusions: QUATTRO improved patient-perceived ability to perform meaningful daily-life activities while maintaining comparable performance on standardized locomotor tests. These results highlight the importance of patient-centered assessments in identifying functional benefits that may guide individualized prosthetic prescriptions for active transfemoral amputees.
Patellar maltracking is among the most common causes of anterior knee pain after total knee arthroplasty (TKA), underscoring the need for accurate prevention and treatment. Therefore, the purpose of this narrative review is to provide a comprehensive overview of current evidence on post-TKA tracking, focusing on component alignment, preoperative patient assessment, and revision treatment options. A PubMed database search was performed, leveraging the literature from the last 20 years, and the results were qualitatively synthesized. According to current studies, several precautions should be taken to prevent patellofemoral stress and, consequently, patellar maltracking, such as avoiding internal rotation, valgus alignment, and excessive flexion of the femoral component and internal rotation of the tibial component. Regarding alignment strategies, kinematic alignment appears to offer potential benefits over mechanical alignment in certain functional outcomes and patient satisfaction scores. However, these differences should be interpreted cautiously as they may not always exceed the minimal clinically important difference. Furthermore, recent evidence indicates that quadriceps biomechanics influence TKA outcomes, potentially suggesting that conventional surgical approaches may need to be individualized, though these preliminary findings require prospective validation. Currently, robotic-assisted surgery represents a developmental direction for patient-tailored interventions and offers great promise for better prosthesis customization to the individual patient. Integration of imaging data with dynamic soft-tissue assessment enables more predictable reconstruction of joint kinematics. Regarding surgical treatment, the selection of specific methods requires a prior clinical and radiographic assessment. Indications range from patellar maltracking direction and component malrotation to patient preferences and rehabilitation potential. Ultimately, the future of TKA relies on personalized interventions to prevent complications and improve patient outcomes. This evolution is driven by the shift from mechanical alignment to kinematic alignment, alongside quadriceps tendon assessment and intraoperative robotic-assisted measurement, all aimed at optimizing the accuracy of implant positioning.
Background/Objectives: Titanium alloy Ti6Al4V remains the gold standard in dental implantology due to its excellent mechanical properties, corrosion resistance, and biocompatibility. However, implant-associated infections and insufficient osseointegration continue to represent major clinical challenges, mainly related to bacterial biofilm formation and suboptimal surface–tissue interactions. Biofilm formation refers to the adhesion, accumulation, and growth of microbial communities embedded within a self-produced extracellular polymeric matrix on implant surfaces, which contributes to bacterial persistence and resistance to host defense mechanisms. This review aims to critically evaluate recent advances in multifunctional bioceramic coatings for dental implants, with a particular focus on zirconia (ZrO2)-based systems and their antibacterial mechanisms. Methods: A structured literature analysis was conducted using major scientific databases including PubMed, Scopus, and Web of Science, focusing mainly on studies published between 2015 and 2025 related to CaP, Ag, and ZrO2-based coatings for dental implants. The review examines their physicochemical properties, antibacterial strategies, ion release behavior, and biological responses, including osteogenic activity and biofilm inhibition. Particular attention is given to hybrid systems integrating multiple functional phases. Results: CaP coatings exhibit excellent osteoconductivity and promote early osseointegration but show limited intrinsic antibacterial activity. Ag-based coatings provide strong broad-spectrum antimicrobial effects through controlled Ag+ ion release, although concerns regarding cytotoxicity and dose-dependent responses remain. ZrO2 coatings significantly enhance corrosion resistance and surface stability, while their antibacterial performance can be improved through nanostructuring, laser surface modification, and ionic doping. Hybrid Ag–CaP–ZrO2 coatings demonstrate improved antibacterial activity, enhanced corrosion resistance, and better regulation of ion release kinetics and osteogenic response compared with single-component coating systems. Conclusions: Multifunctional bioceramic coatings represent a promising strategy for improving the performance of dental implants and addressing the dual challenge of infection control and tissue integration. However, challenges remain regarding long-term stability, controlled ion release, and limited clinical validation. Future research should focus on the development of smart, stimuli-responsive coatings and standardized evaluation protocols to facilitate clinical translation.
Background: Elderly patients often experience difficulty adapting to occlusal reconstruction. Therefore, accurate bite registration is mandatory to ensure precise transfer of the established maxillomandibular relationship to the definitive prosthesis. However, conventional bite registration methods may compromise reproducibility because of deformation of registration materials and instability of mucosa-supported record bases. Methods: A 65-year-old woman with the primary complaints of unstable occlusion and difficulty in mastication underwent occlusal reconstruction. After occlusal stabilization using provisional crowns, bridges, and removable partial dentures, definitive impressions were made with and without the provisional restorations. The casts were scanned, and the digital datasets were superimposed to reproduce the established occlusal morphology of the provisional restorations. This occlusal morphology was used to design a tooth-supported computer-aided design-computer-aided manufacturing (CAD-CAM)-fabricated milled provisional restoration. Following intraoral verification of occlusal stability, the milled provisional restoration served as a mounting guide for the working casts on an articulator. Definitive crowns, bridges, and removable partial dentures were then fabricated. Results: Following comprehensive prosthodontic rehabilitation with definitive prostheses, occlusal stability and masticatory function improved, and the patient was satisfied with the functional outcomes of treatment. Conclusions: A tooth-supported CAD-CAM-fabricated milled provisional restoration used as a bite registration device enables potentially more consistent transfer of the maxillomandibular relationship while avoiding mucosal displacement and material deformation. This technique, which integrates digital and conventional workflows, may provide a new option for addressing adaptation challenges in occlusal reconstruction.
Objectives: Periprosthetic joint infections represent a serious complication following joint arthroplasty, often leading to significant morbidity, with an economic and social impact on the health system. Timely diagnosis of periprosthetic joint infections remains a major challenge. Our study aimed to investigate the diagnostic value and accuracy of several markers, including the neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, and C-reactive protein-to-serum-hemoglobin ratio in revision surgery for periprosthetic joint infections. Methods: A total of 251 revision arthroplasty cases, including 137 cases of periprosthetic joint infections and 114 cases of aseptic revision arthroplasty, were included from the time span January 2016 to May 2025. The diagnostic value and accuracy of the C-reactive protein-to-hemoglobin ratio, neutrophil-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio were evaluated using sensitivity, specificity, and receiver operating characteristic (ROC) analysis with area under the curve analysis. Results: The highest diagnostic performance was obtained by the C-reactive protein-to-hemoglobin ratio, yielding an AUC of 0.859 (SE = 0.0263, 95% CI: 0.809-0.899). This ratio also demonstrated a strong discriminative capacity, with a threshold of >0.0667, sensitivity of 80.45%, and specificity of 85.96%. For the neutrophil-to-lymphocyte count ratio and monocyte-to-lymphocyte count ratio, we obtained an AUC of 0.615 (95% CI: 0.551-0.676) and 0.620 (95% CI: 0.556-0.680), respectively, demonstrating lower sensitivity and specificity than the C-reactive protein-to-hemoglobin ratio. Conclusions: The C-reactive protein-to-hemoglobin ratio demonstrated better diagnostic strength in detecting periprosthetic joint infections, with superior sensitivity and specificity compared to the neutrophil-to-lymphocyte count ratio and monocyte-to-lymphocyte count ratio. Our findings offer new insights into the accurate and early diagnosis of periprosthetic joint infections in cases requiring revision surgery and suggest incorporating these new biomarkers and ratios into the diagnostic algorithm. Future large-scale studies are further needed to validate these results and facilitate their clinical use.
Background/Objectives: 3D printing of removable dentures and temporary crowns and bridges is currently one of the fastest-developing technologies in prosthetic dentistry. However, little is known about the effect of different beverage solutions on the strength and color of 3D-printed denture resins. The study aimed to determine the effect of coffee, red wine, 40% ethyl alcohol, and water (reference samples) on six 3D-printed denture resins (Denture 3D+ (Nexdent); Vita Vionic (Vita), Lucitone Digital Print 3D (Dentsply), DX Denture Flex (Dentex); Formlab Denture Base (Formlabs, Optiprint Dentona). Materials and Methods: Resin samples measuring 3.3 & times; 10 & times; 65 mm (144 total) and disks 1 & times; 20 mm (108 total) were produced using an Asiga printer. The printed materials were then stored in coffee, red wine and distilled water and vodka for 30 days. After this time, they were subjected to a flexural strength (FS) test and the measurement of color change (CC), and compared to reference samples measured before contact with the solutions. One- and two-way ANOVA were used for statistical analysis to compare samples before and after contact with the solutions. Results: The vodka solution affected the materials' FS-the strength was reduced from 10% (Lucitone) to 88% (Detax). For the sample with the most significant FS reduction, the elastic modulus could not be determined. The largest CCs were observed for coffee (E = 22.66 +/- 1.26), and red wine (E = 21.04 +/- 0.70), whereas vodka had the least effect on CC (Lucitone E = 1.04 +/- 0.41 and Form Labs E = 1.31 +/- 0.85). Conclusions: 3D-printed resins are susceptible to the effects of commonly consumed substances, such as coffee, vodka, and red wine. When designing and manufacturing removable prosthetic restorations, it is necessary to carefully consider the dietary habits of patients and the materials from which the removable prosthetics are printed.
Background: Return to play (RTP) after total hip arthroplasty (THA) is increasingly expected by younger and more physically active patients. Current activity recommendations remain heterogeneous and are largely derived from expert opinion and indirect biomechanical modelling approaches, rather than direct in vivo biomechanical evidence. The aim of this article is to systematically map and synthesize the evidence from instrumented hip implant studies and to clarify how direct in vivo telemetry data can inform RTP counselling after THA. Methods: A scoping review was conducted according to a predefined Open Science Framework protocol and reported following PRISMA-ScR guidelines. MEDLINE (PubMed) and Scopus were searched from inception. Peer-reviewed clinical studies reporting direct in vivo biomechanical measurements obtained from instrumented hip implants were included. Conference proceedings, technical notes, reviews, and in vitro or computational-only studies were excluded. Data were extracted and synthesized descriptively according to activity domain, biomechanical variables, and implant technology. Results: Fifty studies met the inclusion criteria. Early investigations established feasibility and evolved from wired strain-gauge systems to fully implantable telemetric prostheses capable of measuring three-dimensional forces, moments, and friction-related parameters. Across cohorts, level walking consistently produced peak hip contact forces of approximately 2–3 times body weight, serving as a clinically meaningful reference loading envelope. Several recreational activities—including cycling, aquatic exercise, Nordic walking, and most gym-machine exercises—generally remained within or close to this range when performed with controlled technique. In contrast, certain rehabilitation tasks, forward-bent postures, lifting maneuvers, and perturbation events generated loads equal to or exceeding those observed during walking. Importantly, frictional moments and load direction showed substantial variability and may be more relevant to implant fixation than peak force magnitude alone. Conclusions: Instrumented hip implants provide objective biomechanical benchmarks that support principle-based and individualized RTP counselling, grounded in directly measured mechanical exposure rather than sport classification alone.
Background/Objectives: The development of high-performance biocompatible polymers such as zirconium-reinforced polyether ether ketone (BioHPP®) has expanded the range of materials available for implant-supported prostheses, traditionally limited to metal alloys and zirconia. Due to its favorable mechanical properties and elastic modulus similar to cortical bone, BioHPP® has been proposed as a potential alternative in implant prosthodontics. This systematic review aimed to analyze the biomechanical behavior of zirconium-reinforced PEEK and assess its advantages and limitations in implant prosthetic applications. Methods: A systematic review was conducted in accordance with PRISMA 2020 guidelines, including studies published between 2011 and 2025 that evaluated the performance of BioHPP in implant prosthetic applications. Results: The search strategy identified 34 studies that met the inclusion criteria. The included studies evaluated mechanical properties such as fracture resistance, elastic modulus, stress distribution, and peri-implant tissue response. Zirconium-reinforced PEEK demonstrated fracture resistance values reaching up to 1623.31 N and an elastic modulus of approximately 4 GPa, comparable to cortical bone. Several studies also reported favorable stress distribution patterns and reduced mechanical complications when compared with conventional metallic materials. Conclusions: Zirconium-reinforced PEEK exhibits promising biomechanical characteristics for use in implant-supported prostheses, particularly due to its fracture resistance and bone-like elastic modulus. However, the available evidence is predominantly based on in vitro and finite element studies. Long-term clinical trials are required to confirm its clinical performance and establish definitive recommendations for routine use.
Background/Objectives: The stability of complete dentures is strongly influenced by the biomechanical properties of the oral mucosa, whose heterogeneity results in non-uniform load distribution, while its clinical evaluation remains predominantly qualitative. This article proposes a theoretical differential hypothesis aimed at providing a conceptual mathematical framework for interpreting the relationship between mucosal resilience and load distribution in complete dentures. Methods: The denture-mucosa system was represented along a one-dimensional coordinate, defining resilience R(x) and pressure P(x) as continuous functions related by a first-order differential equation, interpreted through elementary principles of differential calculus. Results: A theoretical simulation based on physiological parameters (F = 50 N, Young’s modulus 19.75 MPa, R = 2 mm) highlights that areas of thinner mucosa tend to behave as stress concentration points, while spatial variability of resilience generates deformation gradients potentially associated with prosthetic instability. Conclusions: The model, although simplified and non-predictive, provides a coherent interpretative framework and can support the integration of biomechanical parameters into clinical reasoning and prosthetic planning. No clinical recommendations should be derived from this model until experimental validation has been performed.
Background/Objective: Accurate digital recording of implant position is essential for achieving passive fit and predictable outcomes in complete-arch implant-supported prostheses. However, complete-arch cases remain challenging because of increased inter-implant distances, limited anatomical landmarks, soft tissue mobility, scan body-related variables, and cumulative errors during data acquisition and file registration. This narrative review aims to evaluate current intraoral and extraoral digital implant position recording techniques from a clinical decision-making perspective. Methods: A structured narrative literature search was conducted in PubMed from database inception to 15 May 2026 and was supplemented by manual screening of reference lists of key systematic reviews and eligible articles. Systematic reviews, meta-analyses, clinical studies, comparative in vitro studies, dental technique articles, and clinical reports relevant to complete-arch digital implant position recording were considered. Higher-level and clinically relevant evidence was prioritized, whereas technique reports were included primarily for emerging workflows with limited clinical evidence. Results: Intraoral techniques include non-splinted and splinted scan body protocols, calibrated implant scan bodies, calibrated frameworks, and auxiliary reference strategies. These methods may be clinically efficient but remain sensitive to scan path, scanner technology, landmark availability, scan body design, implant distribution, and operator-related factors. Extraoral techniques include stereophotogrammetry, camera- or smartphone-assisted photogrammetric systems, reverse impression workflows, and laboratory scanner-based digitization. These approaches may reduce intraoral stitching errors in complex edentulous arches, but usually require complementary datasets for soft tissue morphology, prosthetic contours, antagonist dentition, and maxillomandibular relationships. Conclusions: Direct intraoral scanner (IOS) protocols may be appropriate in favorable complete-arch situations with accessible scan bodies, limited inter-implant distances, and stable reference geometry. In clinically demanding cases requiring greater cross-arch accuracy, stereophotogrammetry, intraoral photogrammetry, or calibrated scanning approaches may provide more controlled implant position recording. Reverse impression and model-based workflows are particularly useful when a verified interim prosthesis, verification jig, or cast-based reference is available. Regardless of the selected technique, accurate integration of implant coordinates with soft tissue, prosthetic contour, antagonist arch, and occlusal data remains essential.
Background: The Mercer Universal Prosthesis (MUP), designed with a default “neutral” (vertical) socket alignment, was developed to simplify transtibial prosthetic fitting, reduce labor costs, and improve access to prosthetic care in low-resource settings. Methods: This present longitudinal study evaluated biomechanical and functional outcomes at baseline, 6 months, and 12 months in 20 transtibial amputees fitted with the MUP. Results: Functional outcomes, assessed using the SF-36, showed significant improvement in overall health scores at 12 months (p < 0.001), while physical function and energy/fatigue domains remained unchanged (p = 0.686 and p = 0.211, respectively). Biomechanically, sagittal kinematics, measured using inertial motion capture, revealed significant limb × time interactions for hip flexion, knee flexion, and ankle plantarflexion. At 6 months, maximum hip flexion (−7°, p = 0.008) and knee flexion (−11°, p = 0.005) of the prosthetic limb were decreased versus baseline. At 12 months, the only observed difference was increased maximum ankle plantarflexion of the intact limb (+5° vs. baseline, p = 0.016). Muscle effort, quantified via the integral of EMG throughout the gait cycle, did not differ significantly between prosthetic and intact limbs across time points. Gait symmetry index (GSI) scores for hip, knee, and ankle range of motion trended toward gradual improvement but without statistical significance (p > 0.05). Conclusions: The MUP performance was maintained over 12 months, with stable biomechanical performance and meaningful quality-of-life gains. These findings support its potential as a cost-effective solution to expand prosthetic accessibility in low- and middle-income countries.
Background/Objectives: Statistical shape modeling (SSM) is used to describe transtibial residual-limb morphology for prosthetic socket design, simulation, and future structural testing. However, conventional intrinsic metrics such as compactness, generality, and specificity may not directly reflect geometric fidelity to the original shape. This study examined the relationship between geometric fidelity and SSM evaluation and assessed a cross-sectional shape representation framework for transtibial residual limbs. Methods: Residual-limb surfaces were acquired from 62 adults with unilateral transtibial amputation using a structured-light 3D scanner while preserving habitual limb posture. Two surface-based registration methods, non-rigid iterative closest point and Bayesian coherent point drift, were compared with a cross-sectional representation in which proximal and distal regions were sectioned separately and reconstructed by strip triangulation. Geometric fidelity to the original mesh was quantified using average symmetric surface distance (ASSD). SSM performance was evaluated using compactness, generality, and specificity. Results: The optimal cross-sectional configuration was 60 sections × 72 points. The proposed method showed the best geometric fidelity (ASSD, 1.30 ± 0.14 mm), followed by Bayesian coherent point drift (1.33 ± 0.14 mm) and non-rigid iterative closest point (1.48 ± 0.48 mm). Compactness was highest for the proposed method, reaching 95% cumulative variance in four modes, compared with five and seven modes, respectively, for the two surface-based methods. In geometry-space evaluation, the proposed method showed the lowest specificity error, while differences in generality were statistically significant but small in magnitude. Conclusions: Intrinsic SSM metrics alone were insufficient to judge registration quality in transtibial residual-limb modeling. The cross-sectional representation preserved the original surface geometry more faithfully than the evaluated surface-based methods while maintaining competitive SSM performance.
Background: Precise implant placement is crucial during inferior alveolar nerve (IAN) bypass in the posterior mandible where bone height above the IAN is limited. This in vitro study compared the accuracy of static computer-assisted implant surgery (sCAIS) and dynamic computer-assisted implant surgery (dCAIS) for implant placement during IAN bypass. Methods: Two cone-beam computed tomography (CBCT) mandibular models with deficient bone height (<7 mm) above the IAN canal, classified as clinical scenario I and clinical scenario II, were used as an in vitro setting. Thirty models per clinical scenario were prepared, after which 60 dental implants were placed in the edentulous area of tooth no. 47. Software-based analysis compared planned and actual implant placements by postoperative CBCT. The two models were compared for deviation in distance to the inferior alveolar nerve (DIAN), entry-3D deviation, entry-2D deviation, apex-3D deviation, apex-vertical deviation, and angular deviation by comparative statistical analysis. Results: Both sCAIS and dCAIS showed less deviation from planned implant position in both scenarios. No statistically significant differences were detected except for angular deviation (sCAIS: 1.73 degrees vs. dCAIS: 1.19 degrees, p = 0.004), including clinical scenario I (sCAIS: 1.65 degrees vs. dCAIS: 1.19 degrees, p = 0.033) and II (sCAIS: 1.98 degrees vs. dCAIS: 1.2 degrees, p = 0.033). Conclusions: Both approaches showed minor deviation in both IAN bypass models, while dCAIS showed better angular control, requiring future in vitro and in vivo research in complex clinical environments.
Background/Objectives: Alveolar ridge atrophy following tooth extraction complicates subsequent prosthetic rehabilitation and implant placement. This systematic review seeks to provide a comprehensive evaluation of existing evidence regarding the effectiveness of xenogeneic bone graft materials in socket preservation, particularly emphasizing their influence on the adjacent soft tissues. Methods: A systematic literature search was carried out across the CENTRAL, Embase, MEDLINE, PubMed, and Scopus databases. The search targeted randomized controlled trials (RCTs) published in English between January 2015 and September 2025 that examined xenogenic bone grafts used for ridge preservation in comparison either to spontaneous socket healing or to other types of grafting materials. The primary outcomes of interest were bone regeneration and alterations in soft tissues. Multiple independent reviewers performed study screening, data extraction, and risk of bias evaluation using the RoB 2 tool. Results: From 2242 initial records, 4 RCTs (138 patients) met the inclusion criteria. Studies compared xenografts (deproteinized bovine bone mineral with/without collagen), often combined with membranes, to unassisted healing. Augmentation techniques consistently showed a trend toward reduced horizontal and vertical ridge contraction compared to controls, though differences often lacked statistical significance (p > 0.05). Histological analysis revealed significantly less vital bone formation and residual graft particles in xenograft sites versus controls, suggesting volume maintenance is largely graft-dependent. Soft tissue contour changes were evaluated using 3D model scanning. Risk of bias varied, with concerns regarding randomization and reported outcomes in some studies. Conclusions: Xenogenic materials demonstrate comparable clinical effectiveness in preserving alveolar ridge dimensions, though radiographic volume stability may be partially attributed to the slow resorption of the graft material itself rather than new bone formation.
Background/Objectives: Wettability is a key surface property of denture base resins and is related to denture retention through interfacial cohesive–adhesive forces; conversely, compromised material wettability facilitates bacterial adhesion and colonization. Although three-dimensional (3D) printing has become an increasingly popular method for fabricating dentures, there is insufficient evidence regarding the wettability of 3D-printed denture base resins. This study aims to evaluate the wettability of 3D-printed, heat-polymerized, and milled denture base resins by comparing their contact angles. Methods: A search was conducted in MEDLINE, Scopus, and Web of Science, while grey literature was also assessed. The risk of bias was evaluated using the Quality Assessment Tool for In Vitro Studies (QUIN). Meta-analyses were conducted using inverse variance and the random effects model. Results: A total of nine and seven studies were included in the quantitative synthesis comparing 3D-printed denture base resins with heat-polymerized and milled resins, respectively. A statistically significant difference of −6.50 degrees was observed in favor of 3D-printed denture base resins compared to heat-polymerized ones (95% CI: −12.11 to −0.90, I2 = 99%), while the comparison between 3D-printed and milled resins showed a non-statistically significant mean difference (MD: 0.87, 95% CI: −5.08 to 6.82, I2 = 98%). Conclusions: The available in vitro evidence indicates that 3D-printed denture base resins tend to exhibit improved surface wettability compared with heat-polymerized resins and perform similarly to milled resins. However, given the extremely high heterogeneity, these findings should be interpreted with caution, as clinical performance depends on the complex interplay between surface characteristics and microbial adhesion rather than solely on wettability.
Background/Objectives: This cross-sectional observational study was conducted on 146 patients rehabilitated with removable dentures who attended follow-up examinations. Methods: Sociodemographic, medical, prosthetic, and clinical variables were recorded through clinical examination and structured questionnaires. Associations between variables were evaluated using Chi-square and Fisher’s exact tests. Independent predictors were identified through multivariable logistic regression analysis. Results: Denture-related oral mucosal lesions were identified in 81.5% of participants. Denture stomatitis and traumatic ulceration were the most frequently observed lesions. Significant associations were found between lesion occurrence and prosthesis type, nighttime denture wearing, prosthesis stability, and alveolar ridge resorption. Multivariable analysis demonstrated that nighttime denture wearing (OR = 2.84), prosthesis instability (OR = 2.63), complete denture rehabilitation (OR = 1.89), and advanced alveolar ridge resorption (OR = 2.17) were independent predictors of lesion occurrence. Conclusions: A high prevalence of denture-related oral mucosal lesions was observed in this study population; however, the findings should be interpreted within the context of a single-center cross-sectional study.
