Reappearance of AFP was demonstrated in a single rat out of a large control population. At autopsy, this DOCA-hypertensive rat was found to have a form of hepatitis associated with proliferative activity, i.e., cellular unrest, mitotic figures and oval cell hyperplasia. It is submitted that increased AFP synthesis in this animal with spontaneous hepatitis is causally related to hepatocellular regeneration.
During acute HBsAg serum positive viral hepatitis, the surface antigen was not detectable in duodenal bile but was almost always present in gallbladder and hepatic bile when cholecystokinin was intravenously administered. The immunologic nondemonstrability of HBsAg in duodenal bile is probably due to the presence of a factor elaborated by the intestinal mucosa. The possible role played by this factor in the non transmission of type B viral hepatitis via faecal-oral route is suggested.
Squamous cell carcinomas were induced in the hamster cheek pouch with 9,10-dimethyl-1,2-benzanthracene. The process of carcinogenesis was inhibited by phenylphosphate, an inducer of alkaline phosphatase. Orthophosphate and l-phenylalanine, which inhibit alkaline phosphatase, had a promoting effect on tumor formation. The results are in accordance with those of previous studies on the effect of inducers of alkaline phosphatase on chemical carcinogenesis. The effect of the studied substances on carcinogenesis was apparently unrelated to the presence of phenyl or phosphate groups or of steroid rings. The tumor inhibition or promotion seemed to be related to the potential of the tested substances to induce or inhibit alkaline phosphatase activity.
The role of the kidneys in hepatic carcinogenesis was studies in inbred A X C strain male rats ingesting 0.025% N-2-fluorenyldiacetamide. The experimental groups consisted of male rats with both kidney intact and male rats that had the left kidney removed. The incidence of hepatic carcinomas and the number of rats with large carcinomas, multiple carcinomas, poorly differentiated and undifferentiated carcinomas, and metastases was greater in rats with a left nephrectomy. The incidence of cirrhosis was the same in animals in both groups; however, cirrhosis was more severe in degree in the rats with the left kidney removed. Some animals in the latter group also developed carcinosarcomas of the salivary glands. The animals with one kidney apparently were not able to excrete the active metabolites of N-2-fluorenyldiacetamide as readily as the animals with both kidneys intact. The metabolites were then returned to the liver and salivary gland.
Following intravenous injection of mycobacteria in the mouse the bacilli are regularly found in the peripheral nervous system after the 5th day. The peripheral nerves and autonomic ganglia are involved at the level of the perineural cells and the sheath of Schwann. When the organisms are of low virulence (BCG, Mycobacterium intracellulare) the development of the nodules is limited. In the case of a virulent strain (Ravenel) extensive granulomas are found but epitheloid cells, always found in other organs, are constantly absent. In animals previously immunized, the bacilli seem to implant themselves as in the controls, but multiply more slowly; the nodules are more infrequent and the lymphoid infiltration appears earlier with the multiplication of interstitial cells.
Research Articles| October 03 2008 Endarteritis obliterans or Arteriosclerosis obliterans? Subject Area: Further Areas , Oncology , Pathology and Cell Biology Anna Kádár; Anna Kádár 2nd Department of Pathology, Electronmicroscope Laboratory, Semmelweis Medical University, Budapest Search for other works by this author on: This Site PubMed Google Scholar H. Jellinek; H. Jellinek 2nd Department of Pathology, Electronmicroscope Laboratory, Semmelweis Medical University, Budapest Search for other works by this author on: This Site PubMed Google Scholar Zsuzsa Béres Zsuzsa Béres 2nd Department of Pathology, Electronmicroscope Laboratory, Semmelweis Medical University, Budapest Search for other works by this author on: This Site PubMed Google Scholar Experimental Cell Biology (1975) 43 (2-3): 167–172. https://doi.org/10.1159/000162815 Article history Published Online: October 03 2008 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Anna Kádár, H. Jellinek, Zsuzsa Béres; Endarteritis obliterans or Arteriosclerosis obliterans?. Experimental Cell Biology 31 December 1975; 43 (2-3): 167–172. https://doi.org/10.1159/000162815 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsPathobiology Search Advanced Search Article PDF first page preview Close Modal Keywords: Thromboangiitís obliterans, Buerger's disease, Arteriosclerosis, Electron microscopy 1975Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. You do not currently have access to this content.
An outbreak of approximately 200 cases of acute hemorrhagic conjunctivitis is described in Prekmurje, a northern province in Yugoslavia. The epidemic was caused by enterovirus type 70, serologically identical with the causative agents of similar outbreaks in London and Japan. The origin of the outbreak could not be elucidated but a link was seen between this case and a small outbreak in Veenendaal in the Netherlands.
Research Articles| October 03 2008 Geographic Patterns of Immunity and Vascular Disease Subject Area: Further Areas , Oncology , Pathology and Cell Biology Werner Dutz; Werner Dutz Medical College of Virginia, Richmond, Va.; Kinderklinik Universität Graz, Graz; Pahlavi University Medical School, Shiraz; Medical College of Virginia, McGuire VA Hospital, Richmond, Va.; Pahlavi University, Shiraz Search for other works by this author on: This Site PubMed Google Scholar Erich Rossipal; Erich Rossipal Medical College of Virginia, Richmond, Va.; Kinderklinik Universität Graz, Graz; Pahlavi University Medical School, Shiraz; Medical College of Virginia, McGuire VA Hospital, Richmond, Va.; Pahlavi University, Shiraz Search for other works by this author on: This Site PubMed Google Scholar Hushang Ghavami; Hushang Ghavami Medical College of Virginia, Richmond, Va.; Kinderklinik Universität Graz, Graz; Pahlavi University Medical School, Shiraz; Medical College of Virginia, McGuire VA Hospital, Richmond, Va.; Pahlavi University, Shiraz Search for other works by this author on: This Site PubMed Google Scholar Elfriede Kohout; Elfriede Kohout Medical College of Virginia, Richmond, Va.; Kinderklinik Universität Graz, Graz; Pahlavi University Medical School, Shiraz; Medical College of Virginia, McGuire VA Hospital, Richmond, Va.; Pahlavi University, Shiraz Search for other works by this author on: This Site PubMed Google Scholar Karim Vessal Karim Vessal Medical College of Virginia, Richmond, Va.; Kinderklinik Universität Graz, Graz; Pahlavi University Medical School, Shiraz; Medical College of Virginia, McGuire VA Hospital, Richmond, Va.; Pahlavi University, Shiraz Search for other works by this author on: This Site PubMed Google Scholar Experimental Cell Biology (1975) 43 (2-3): 173–181. https://doi.org/10.1159/000162816 Article history Published Online: October 03 2008 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Werner Dutz, Erich Rossipal, Hushang Ghavami, Elfriede Kohout, Karim Vessal; Geographic Patterns of Immunity and Vascular Disease. Experimental Cell Biology 31 December 1975; 43 (2-3): 173–181. https://doi.org/10.1159/000162816 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsPathobiology Search Advanced Search Article PDF first page preview Close Modal Keywords: Epidemiology of vascular disease, Immunity and vascular disease This content is only available via PDF. 1975Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. You do not currently have access to this content.
Research Articles| October 03 2008 Phlebitis saltans, Symptom or Disease Entity? Subject Area: Further Areas , Oncology , Pathology and Cell Biology A. Bollinger; A. Bollinger Departments of Internal Medicine and of Pathology, University of Zurich, Zurich Search for other works by this author on: This Site PubMed Google Scholar H.J. Leu H.J. Leu Departments of Internal Medicine and of Pathology, University of Zurich, Zurich Search for other works by this author on: This Site PubMed Google Scholar Experimental Cell Biology (1975) 43 (2-3): 228–229. https://doi.org/10.1159/000162825 Article history Published Online: October 03 2008 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation A. Bollinger, H.J. Leu; Phlebitis saltans, Symptom or Disease Entity?. Experimental Cell Biology 31 December 1975; 43 (2-3): 228–229. https://doi.org/10.1159/000162825 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsPathobiology Search Advanced Search Article PDF first page preview Close Modal Keywords: Endangiitis obliterans, Morbus Behçet, Collagen vascular disease, Panphlebitis chronica, Salicylic acid This content is only available via PDF. 1975Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. You do not currently have access to this content.
