Objective: The purpose of this study was to examine electrocardiographic ventricular arrhythmia predictors in patients with schizophrenia by comparing with healthy controls. Methods: The study included 100 patients with schizophrenia and 100 healthy controls. Electrocardiography (ECG) was performed on all participants in resting position. T-wave peak to end (Tp-e), QT ranges, P-wave dispersion (Pd), and R-R range were measured. Then, the Schizophrenia Positive and Negative Syndrome Scale (PANSS) and the Calgary Depression Scale for Schizophrenia (CDSS) were applied to the schizophrenia group. Results: The PANSS positive symptom subscale was calculated as 10.41 (SD = 2.27), the negative symptom subscale was calculated as 14.44 (SD = 5.42), and the overall functionality level was calculated as 27.04 (SD = 5.43). The mean CDSS score was determined to be 3.74 (SD = 2.15). No differences were detected in the heart rate measurements of the patient and control groups in ECG results (P = .427). The minimum QT interval and minimum Tp-e wave times were found to be low in the patient group (P < .001 for both intervals). Corrected QTc dispersion, Pd, Tp-e dispersion, and QT dispersion were found to be higher in the patient group than in healthy controls (P < .001 for all intervals). Discussion: Based on our results, it is possible to speculate that patients with schizophrenia are at a risk of developing cardiac arrhythmia and cardiac dysfunction if they do not receive treatment. For this reason, clinicians should pay attention to cardiac transmission problems when organizing the treatment of patients. Further studies should be conducted to determine cardiac problems in patients with schizophrenia.
Objective:This study aimed to reveal a process model of the relations between automatic thoughts, dysfunctional attitudes, social problem-solving skills, and social media addiction. In this context, the aim was to investigate the mediating effect of automatic thoughts and social problem-solving skills in the relationship between intermediate beliefs and social media addiction. Methods:This study included 56 male and 107 female young adults aged 18-25 years who were referred to the psychiatry outpatient clinic of Yenimahalle Training and Research Hospital, Ankara, Turkey. The participants completed sociodemographic data form, social problem-solving inventory revised form, social media addiction scale, dysfunctional attitudes scale short form, and automatic thoughts questionnaire. In the data analysis, the effect and mediation were tested by the process method. Results: Dysfunctional attitudes positively affected social media addiction and automatic thoughts and negatively affected social problem solving. According to this, the effect of dysfunctional attitudes on social media addiction was mediated by automatic thoughts and social problem solving. Conclusion: In this sense, both cognitive and behavioral processes can be useful in the treatment of social media addiction, and cognitive behavioral therapies can be an effective option.
Headache is generally perceived as a negative symptom focused on oneself. However, there are reports suggesting that patients suffering from pain, especially headache, can be aggressive. The precise nature of the link between headache and aggression is not known. Here, we describe a homicidal attack, triggered by headache, in a middle-aged man. The patient’s background and the characteristics of the attack suggested a dissociative behavior. The case shows that headache may be a trigger for homicidal behavior. Case-control studies are needed to determine the prevalence of aggressive tendencies in patients with headache.
Objective:The aim of this study is to examine the relationships between personality traits, psychopathology, and nonverbal immediacy behaviors. The study gains importance because of the fact that personality traits, psychopathology, and the concept of nonverbal immediacy have not been studied together in Turkish culture. Methods: The research sample was created with the convenience sampling method, one of the nonrandom sampling methods. The sample consisted of 336 university students aged 18 and over. In the study, the 10-Item Personality Inventory, Nonverbal Immediacy Scale-Self Report Form (NIS-STr), Symptom Checklist (SCL-90-R), and Communicator Styles Scale were used. To examine the effect of personality traits on SCL-90-R and the effect of SCL-90-R scores on nonverbal immediacy behavior, a structural equation model was used and the path analysis of the model was created. Results: Although it was determined that the scores for conscientiousness, emotional stability, and extraversion in the scale of resilience to the scope of the study did not significantly predict the SCL-90-R scores (P > 0.05), the scores for agreeableness (beta = 0.38, P < 0.05) and openness (beta = 0.38, P < 0.05) predicted the SCL-90-R scores significantly and positively. In addition, it was determined that the scores of other applications from the SCL-90-R were similarly significant surrounding other predictors of NIS-STr scores (beta = -0.30, P < 0.05). Conclusion: It can be stated that personality traits are predictors of psychopathological symptoms. Students' SCL-90-R scores positively predicted the NIS-STr scores in a statistically negative way.
Objective:There are few studies on oxidative stress in patients with post-traumatic stress disorder (PTSD). The thiol/disulfide homeostasis is a new marker of oxidative stress. This study aimed to examine the oxidative DNA damage and thiol/disulfide homeostasis after 6 months in patients who developed PTSD after an avalanche disaster and to compare them with healthy controls.Methods:A total of 31 patients who developed PTSD after 2 consecutive avalanche disasters that occurred in Van on February 4 and 5, 2020, resulting in 42 deaths, and 33 healthy volunteers were included in the study. The patients were followed up by a psychiatrist within the framework of psychosocial intervention during their admission to Yüzüncü Yil University Medical Faculty Emergency Service. The patients monitored for a long time were diagnosed according to DSM-5 diagnostic criteria. The clinical follow-up was evaluated with the post-traumatic stress disorder self-assessment (PTSD-KD) and the impact of events scale. To determine oxidative DNA damage, 8-hydroxy-2-deoxyguanosine (8-OHdG) and deoxyguanosine (dG) levels were determined by isolating leukocyte DNA. Oxidative DNA damage was given as a ratio of 8-OHdG/106dG. Total thiol/native thiol levels were also determined. Disulfide levels were calculated by subtracting native thiol results from the total thiol results and dividing them by 2.Results:It was determined that total thiol and native thiol levels in patients with PTSD were statistically significantly lower than in the healthy control group (P = .001), and the disulfide levels were higher in the PTSD group compared with that in the healthy control group (P = .001). In addition, 8-OHdG, an indicator of DNA damage, was found to be significantly lower in the control group than in the patient group (P = .001).Conclusion:In our study, thiol/disulfide homeostasis was observed to shift toward disulfide in patients with PTSD when compared with healthy controls. The level of 8-OHdG, the indicator of DNA damage, was observed to increase in patients with PTSD. This result indicates that thiol/disulfide homeostasis can be significant in the pathophysiology of oxidative stress in these patients.
