Patients with cardiac implantable electronic devices are usually excluded from MRI examinations due to contraindication for MRI. The MRI-conditional pacemaker system may allow the benefits of MRI (system 1.5T) to be more accessible to pacemaker patients. A 62-year-old man was admitted with acute coronary syndrome and atrial fibrillation. A conventional angiography showed normal coronaries. A cardiac cardioversion revealed a significant sinus node dysfunction and a magnetic resonance imaging (MRI) compatible dual chamber system was implanted. At 6-week follow-up, a cardiac MRI revealed a typical anterior myocardial infarction with diagnostic quality images despite pacemaker. This is one of the first reports of cardiovascular MRI in a patient with MRI-conditional pacing system. (C) 2013 Elsevier Masson SAS. All rights reserved.
Background and aim. - Pulse wave analysis is a pivotal instrument to estimate central hemodynamic parameters. Applanation tonometry on radial and/or carotid arteries is usually used to detect pressure waveforms. Available commercial devices have been validated against invasive catheterism, showing a good agreement of harmonics pattern. In a previous investigation, we observed differences on radial second systolic peak (rSPB2) between two commonly used devices: SphygmoCor (AtCor, Australia) and PulsePen (Diatecne, Italy.). The aim of our study was to further quantify differences on radial and carotid signals from the two devices.Methods. - We measured radial and carotid pressure waveforms in 38 patients where systolic, diastolic blood pressure and heart rate presented minimal changes between measurements. Waveforms were digitally extracted for off-line analysis.Results. - Radial rSBP2, mean arterial pressure, form factor and augmentation index were different with SphygmoCor providing lower values. Carotid augmentation index and form factor were similar. However, carotid systolic pressure (cSBP) from PulsePen was higher that cSBP from SphygmoCor (2.7 +/- 4.4 mmHg, P < 0.001).Conclusion. - PulsePen and SphygmoCor sensors are not equivalent and provide different wave shapes. These differences on wave shape have important consequences on parameters computed from these waveforms with more discrepancy on radial derived parameters such as rSBP2 and mean arterial pressure than on carotid derived parameters. Further studies are required to compare invasive pressure parameters to indices derived from these two devices. (C) 2013 Published by Elsevier Masson SAS.
Objective. - Recent studies have shown a link between prolonged television viewing and cardiovascular (CV) morbidity and mortality. We aimed to estimate the relationship between television viewing and CV risk behaviors and in the adult population of the French West Indies.Patients and methods. - We used data from Consant, a cross-sectional study carried out in 2007 on a representative sample of the adult Guadeloupean population (1005 subjects aged 25-74 years selected by stratified random sampling and interviewed at home by trained investigators working in pairs).Results. - Among respondents who reported watching television for 2 hours or more per day, 46.5% stated practicing no leisure time physical activity, compared with 35.6% among those who reported watching television for less than 2 hours per day. Adjusting for age, sex, education, income, family status, and perceived CV benefits of physical activity, the odds ratio of physical inactivity was estimated at 1.75 (P < 10(-3)) among subjects who reported watching television for 2 hours or more per day, compared with other subjects. A similar relationship was observed when considering dieting to prevent weight gain.Conclusion. - In this representative sample of a French Caribbean population, a strong and very significant relationship was observed between prolonged television viewing and CV risk behaviors. Prolonged television viewing seems common to a lifestyle that is characterized by little physical activity and unhealthy eating habits. This may play a role in social inequalities observed in CV diseases. (C) 2013 Elsevier Masson SAS. All rights reserved.
Aim of the study. - The aim was to see if 40% of caloric restriction can improve in rats, the oxidative stress induced by a high fat diet on liver, heart and aorta, and have a positive impact on the lipoproteins-cholesterol contents.Methods. - Male Wistar rats (n=12) consumed at weaning obesegenic diet. The obese rats were divided into two groups (n=6) each consumed for 4 weeks a normocaloric diet (1,60 MJ) or a calorie restricted diet (40% of energy of the standard diet [0.96 MJ]). A control group (n=6) was fed a standard diet during the experiment.Results. - Caloric restriction decreased cholesterol and low-density lipoproteins-cholesterol, whereas the high-density lipoproteins-cholesterol was elevated. Levels of cholesterol in the aorta and heart were lowered in the group that consumed caloric restriction compared to normocaloric diet. The values of thiobarbituric acid reactive substances and hydroperoxides were lowered in the aorta and the heart. The caloric restriction compared to normocaloric diet increased positively the superoxide dismutase., catalase, glutathione peroxidase and glutathione reductase activities in the heart and those of catalase and superoxide dismutase in aorta.Conclusion. - In obese rats, caloric restriction may play a role in the antioxidant defense of cardiovascular system by reducing proatherogenic cholesterol and lipid peroxidation and increasing the antioxidant activity of some enzymes, which was in favor of reduction of cardiometabolic risk associated with obesity. (C) 2013 Elsevier Masson SAS. All rights reserved.
Aim of the study. - To valorize fish by-products oil by investigating its effects on dyslipidemia, hyperglycemia, reverse cholesterol transport and paraoxonase-1 activity in obese rat.Methods. - Sixteen male Wistar rats were fed a high fat diet. At 400 +/- 10 g, obese rats were randomly divided into two groups: the first received 20% of sardine by-products oil and the second 20% of the edible portion oil. At d28, glycemia and serum lipids concentrations were estimated. High density lipoproteins (HDL2 and HDL3) were separated and their contents and composition in lipids and apolipoproteins were analyzed. Lecithin: cholesterol acyltransferase and paraoxonase-1 activities were assessed.Results. - In group which consumed sardine by-products oil, serum cholesterol and triacylglycerols were reduced (-8% and -36%, respectively). However, glycemia was similar. HDL3-phospholipids, HDL3-unesterified cholesterol and HDL3-apolipoproteins were decreased by 56%, 10% and 12%, respectively. Lecithin: cholesterol acyltransferase activity was increased by 35% and the content of HDL2-cholesteryl esters was elevated by 12%. Serum paraoxonase-1 activity was increased by 25%.Conclusion. - In obese rat, sardine by-products oil may have a protective effect against cardiovascular risk by improving the anti-atherogenic metabolic pathway of cholesterol and triacylglycerols. This anti-atherogenic action is particularly enhanced by the increase in paraoxonase-1 activity which protects lipoproteins from oxidation. (C) 2013 Elsevier Masson SAS. All rights reserved.
