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    Cancer investigation

    Cancer investigation

    JournalISSN 0735-7907eISSN 1532-4192中科院 医学 4区

    年发文量

    研究主题

    论文(4231)

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    1Exploratory Single-Cell Analysis of NK-Annotated Cells Across Marrow Compartments in Prostate Cancer Bone Metastasis
    Kehao Pan,Nianzeng Xing
    2026
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    2Cancer-Associated Fibroblast Exosomes in Breast Cancer: Mechanisms of Tumor-Stroma Crosstalk and Clinical Implications
    Arezoo Ghareh-Hasanlou, Negar Yavari Tehrani-Fard, Parastoo Akbarabadi, Maryam Etesami, Sara Zareian, Roudabeh Behzadi-Andouhjerdi, Zeinab Piravar,Sadegh Babashah
    2026
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    3Assessment of Adverse Drug Reaction, Medication Adherence and Quality of Life in Breast Cancer Patients: A Prospective Observational Study
    Mohamed Akram Ali S, Hariharan B, Sathishkumar K, Somasundram C, Tharun B, Vijayasakthi M
    2026
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    4Psychosocial and Sociodemographic Factors Associated with Perceived Barriers to Physical Activity in Patients Receiving Chemotherapy
    William de Lima Selles, Giovanna Marques Frascoli Dos Santos, Giovanna Lopes, Othavio Ferreira, Beatriz Marques Lima,Adriana Claudia Lunardi

    AIM:To evaluate associations between psychosocial and sociodemographic factors and perceived barriers to physical activity among hospitalized patients receiving chemotherapy. MATERIALS AND METHODS:This cross-sectional study included 163 patients hospitalized for chemotherapy. Anxiety, depressive symptoms, self-efficacy, and perceived barriers were assessed using validated instruments. Spearman and partial Spearman correlations examined associations between psychosocial variables and perceived barriers, and exploratory analyses examined individual barriers. Multiple linear regression evaluated independent associations with the mean score of the 21-item barrier questionnaire, adjusting for age, sex, body mass index, and self-reported race/color. RESULTS:The most frequently reported barriers were the perception that disease prevented engagement in physical activity, physical limitations, and lack of energy. Overall perceived barriers were positively associated with anxiety and depressive symptoms and inversely associated with self-efficacy. In the multivariable analysis, higher anxiety symptoms, older age, and self-reported Black race/color were independently associated with greater perceived barriers. Depressive symptoms and self-efficacy were not independently associated after adjustment. CONCLUSIONS:Perceived barriers to physical activity were common among hospitalized patients receiving chemotherapy. Anxiety, older age, and self-reported Black race/color were independently associated with greater perceived barriers. These findings highlight the importance of individualized approaches addressing physical and psychosocial barriers during cancer treatment.

    2026
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    5Clinical, Allied Health, and Research/Advocacy Professionals’ Perspectives on Body Image and Support Needs for Young Adults with Cancer; A Qualitative Study
    Emilia Graham,Abigail Fisher, Caroline Buck,Phillippa Lally,Madison F Vani, Catherine M Sabiston, Catalina Jaramillo Quintero, Nicole Collaço

    Body image dissatisfaction is a significant concern for young adults with cancer (YAC), yet little is known about the views of clinical, allied health, research, and advocacy professionals who support them. This study aimed to understand their perspectives on body image challenges for YAC, and how best to provide support. Individuals working with YAC were recruited internationally via snowball sampling. Online semi-structured qualitative interviews were conducted, and data were analysed using the Framework Method. Thirteen participants were interviewed. Three themes were identified: (1) Constructing meaning around body changes; (2) Engaging with body image support: barriers and facilitators; and (3) Structural constraints and inequities in BI support/care. Participants identified the need for tailored, patient centred care, peer support and better professional training to address BI distress in YAC. Support should be timely, adaptable to individual needs and sustained across the care pathway.

    2026
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    高被引作者

    作者引用发文
    Wendy J Levin69521
    J A Udove69521
    Steven G Wong69521
    MF PRESS69521
    LA JONES69521
    DE KEITH69521
    Dennis J. Slamon69521
    Stuart Grossman9549
    Alberto Gabizon8012
    John Nemunaitis8008

    高产作者

    作者引用发文
    Gary Herbert Lyman29635
    Nicole M Kuderer13322
    Alfred I. Neugut34718
    Dawn L Hershman30717
    Maurie Markman9616
    Jacob Lokich16615
    Howard A. Skip Burris III30511
    Wright Jason D17611
    George Fountzilas29610
    Janice P. Dutcher21810

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