Evaluation of the performance of N-doped graphene, synthesized by solvothermal method, as anode for Na-ion and Li-ion batteries
Traditional medicine plays a crucial role in healthcare and disease management in African communities; however, the quality and toxicity of these remedies remain largely unknown, particularly concerning the chronic conditions that are managed by traditional medicines.Despite the widespread use of Kigelia africana as a traditional medicine for chronic conditions, its genotoxic and mutagenic effects remain unclear.This study aimed to address this knowledge gap by examining the genotoxic and mutagenic properties of aqueous and ethyl acetate crude extracts of Kigelia africana fruits obtained from the Kazungula District of Zambia.The study used quantitative fluorescence microscopy to determine mutagenicity and genotoxicity and compared the results with the Ames results obtained in this study.The study found that the aqueous extract had no effect on cell viability, while the ethyl acetate extract caused a dose-dependent reduction in cell viability.The effects of the fruit extracts on His+ revertants were comparable to those of the negative control, showing no mutagenic effects.The study also found that the average nuclear area of Vero cells increased significantly with the highest concentration of the ethyl acetate fruit extract, but there was no significant effect on the multi+dual/mononucleated Vero cell ratio following a 48-hour exposure.This study demonstrated for the first time that K. africana fruit extracts are not cytotoxic and do not have mutagenic potential and that the extracts do not exhibit genotoxic effects at therapeutic doses.
While the world is grappling with the SARS-CoV-2 pandemic and striving to minimize the damage caused, another emerging virus called Monkeypox Virus (MPXV) has surfaced, capturing widespread attention and instilling panic among people.There is a fear that this new virus could lead to a scenario similar to, if not worse than, the ongoing COVID-19 crisis.Hence, the objective of this work is to provide an overview of the monkeypox disease to shed light on the characteristics and behavior of this emergent disease, to explore reliable and possible diagnostic methods, and delve into the available preventive and therapeutic measures, including viable drugs and approved vaccines, to mitigate the impact of the illness.Many enigmas still surround this emergent disease, which makes it crucial to emphasize the importance of clarifying its progression and establishing effective control measures; by doing so, we can learn from past experiences and avoid repeating the errors that occurred during the COVID-19 pandemic.
Copper-driven catalyst design for improved oxygen reduction reactions in carbon-based materials
A new emerging virus named Monkeypox virus (MPXV) has recently gained significant attention, captured the headlines and spread panic among people due to the threat it poses to their health and well-being.This review paper aims to provide an overview of the virology of this novel virus, shedding light on its morphology, genetics, and process of replication.Furthermore, it delves into the origin of the virus and describes the diverse routes through which it spreads, as well as our body's immune response against it.Understanding the fundamental characteristics of the MPXV is crucial in order to comprehend its potential impact on public health.Also, exploring its genetics, and studying its replication would aid in the development of effective diagnostic methods and potential treatments, and to identify specific genes and proteins that contribute to its virulence and pathogenicity.While the likelihood of MPXV becoming a pandemic may be low, comprehensive knowledge about the virus and its modes of transmission is crucial to prevent the possibility of large-scale outbreaks.By staying informed and implementing appropriate preventive measures, we can effectively mitigate the impact of this emerging virus and safeguard public health.
