Cardiac magnetic resonance (CMR) late gadolinium enhancement (LGE) characterises infarct scar and microvascular obstruction (MVO) after myocardial infarction (MI). Left-ventricular ejection fraction (LVEF) remains the reference prognostic marker; data on LGE tissue markers from South Asian populations, in whom delayed presentation produces larger scars, are limited. We examined the association of LGE scar burden and MVO with one-year all-cause mortality. Single-centre, retrospective observational cohort of 260 patients with MI referred for clinically indicated CMR. LGE scar burden (
To assess myocardial positron emission tomography (PET) positivity after negative or low-grade bone scintigraphy, while distinguishing test discordance from independently confirmed cardiac amyloidosis. PubMed, Scopus and Web of Science were searched through 5 August 2026, with targeted source assessment through 2 October 2026. Negative and low-grade imaging denoted Perugini grades 0 and 1, respectively; study-defined negative results were described separately. Eligibility required linked PET and bone-scan results with an extractable denominator. Acquisition modality, PET thresholds and cardiac reference standards were examined. A restricted synthesis required documented tomographic acquisition; a broader three-report synthesis was exploratory. Nine reports provided extractable paired results. In the hereditary transthyretin subgroup examined with carbon-11 Pittsburgh compound B, 20/23 participants were PET-positive after excluding one acquired, domino-transplant case. The exploratory pooled proportion was 87.0
Myocardial infarction with non-obstructive coronary arteries (MINOCA) and acute myocarditis (AM) often present with overlapping clinical features and biomarker profiles, making early differential diagnosis challenging. Cardiovascular magnetic resonance (CMR) is the reference modality for etiological assessment through functional evaluation and multiparametric tissue characterization. The aim of this study was to compare clinical and CMR characteristics of patients with MINOCA and suspected AM, and to identify imaging features enabling accurate differentiation. We retrospectively analyzed 127 consecutive patients undergoing CMR (February 2021–October 2024): 62 with suspected MINOCA and 65 with suspected AM. Clinical data, laboratory findings, ECG, and CMR parameters (cine imaging, T1/T2 mapping, extracellular volume [ECV], and late gadolinium enhancement [LGE]) were assessed. MINOCA patients were older (median 59 years) and predominantly female (64.5
To describe a sequential multimodality imaging strategy for transseptal access during cryoballoon ablation in a patient with cor triatriatum sinister (CTS). Methods: A 55-year-old man with paroxysmal atrial fibrillation and CTS underwent preprocedural cardiac computed tomography (CCT), followed by real-time transesophageal echocardiography (TEE), contrast confirmation, and fluoroscopic guidance during the procedure. Results: CCT demonstrated pulmonary vein drainage into a Proximal Chamber (Posterior-Superior), separated from the Distal Chamber (Anterior-Inferior) by a membrane. Real-time TEE identified and confirmed an anterosuperior transseptal site, with septal tenting before needle passage. After a single BRK needle puncture, contrast confirmed access to the pulmonary-vein-containing chamber, allowing advancement of the FlexCath Advance catheter (Medtronic) and cryoballoon isolation of all 4 pulmonary veins without procedural complications. Conclusion: In CTS, transseptal access should be tailored to the individual atrial anatomy. Sequential use of CCT, real-time TEE, contrast, and fluoroscopy can provide complementary information at the successive stages of the procedure.
