Introduction: Atypical infections are often considered as a potential etiology for men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). We aimed to describe the prevalence of atypical infections in this patient population to inform clinical management for male patients complaining of pelvic pain. Methods: We retrospectively reviewed patients at a single center from January 2016 to January 2019. We included patients with CP/CPPS Type III diagnosed with pelvic or genital pain in the absence of bacterial infection. All patients underwent an atypical infection panel. The primary outcome measure was the presence of any atypical infection. Results: In total, 345 patients met the inclusion criteria. Of those, 9/345 (2.6%) had an atypical infection (5 mycoplasma and 4 ureaplasma). The mean age of patients with positive atypical infections was 34 compared to the overall study population (44 years, P=0.01). Two patients with atypical infections were also followed for infertility. Urinalysis was available for 6 of the 9 patients with positive atypical infection: 50% (3 out of 6) were normal and 50% (3 out of 6) had >5 WBC/hpf. Symptoms resolved in 66% (2 out of 3) of the patients with positive atypical infection with available follow-up data. Conclusion: Atypical infectious agents were uncommon causes of CP/CPPS. Screening for atypical microbes such as chlamydia, ureaplasma, or mycoplasma may not be necessary for male patients complaining of pelvic or genital pain.
Introduction: Urethral, penile, and scrotal cancers are rare and represent less than 1% of all malignancies. However, they are associated with a high mortality rate and have a significant effect on patients’ quality of life. Penile and urethral cancers comprise 0.6% of all urological cancers. Because of ethnic, geographical, and cultural diversity, risk factors and cancer patterns vary in different communities. We aimed to provide valid information on the prevalence, incidence, and epidemiology of urethral, penile, and scrotal cancers using the National Registry on Cancer of Iran. Methods: This retrospective study of 465 patients included all known cases of urethral, penile, and scrotal cancers from the Department of National Registry on Cancer at the Ministry of Health and Medical Education in Iran during 2004-2015. This study examined the demographic characteristics of patients and discussed the risk factors and possible causes of the above-mentioned cancers. Results: The mean ±SD age at the time of registration was 58.49±20.82 years. The highest and lowest proportions of cases belonged to Tehran/Alborz (14.2%) and Mazandaran (0.65%) provinces, Iran, respectively. Regarding the distribution of records according to a year of registration, these cancers were more prevalent in 2014, and less prevalent in 2004. Conclusion: Urethral, penile, and scrotal cancers were more common in Tehran and Alborz. There was a strong possibility that the prevalence of these cancers is linked to the industrial nature of Tehran and Alborz and the prevalence of human papillomavirus.
Introduction: Social distance is important for reducing the spread of the new COVID-19 pandemic, especially in public places. In addition, urban stores are one of the crowded places where observing social distance is considered necessary. Therefore, the present study aimed to evaluate the social distance between customers in urban stores during the outbreak of the COVID-19 pandemic using a simulation method. Materials and methods: Research data were collected from the closed-circuit television footage of a store from a hypermarket in Iran, and then customers’ social distance was analyzed through their movement behaviors by two modes of 1 and 2-meter distance using software similar to the Pathfinder simulator. Further parts of the urban store required corrections considering the first scenario and the two-meter distance between people compared to the second scenario and the one-meter distance between them. Results: Based on simulation results, dense areas were identified in different sections of the hypermarket, namely, places where the shelves distance was 1 meter to 2 meters. More precisely, this research provided a method for evaluating different parts of the store in terms of population density regarding maintaining social distance. Conclusion: several suggestions were presented to stores for maintaining social distance based on research findings.
Since 31 December 2019, the coronavirus disease 2019 (COVID-19) resulted in a state of hyperinflammation syndrome and multiorgan failure. In areas with pandemic outbreaks, despite several emerging vaccines, supportive treatments to mitigate fatality rates were required. Growing evidence suggests that several small RNAs such as microRNAs (miRNAs) and short interfering RNA (siRNA) could be candidates for the treatment of COVID-19 by inhibiting the expression of crucial virus genes. small RNAs by binding to the 3′-untranslated region (UTR) or 5′-UTR of viral RNA play an important role in COVID-19-host interplay and viral replication. In this review, the authors sought to specify the efficacy and safety of miRNAs and siRNA expressions of patients with COVID-19, which has an axial role in the pathogenesis of human diseases.
Introduction: Self-efficacy is a construct that can greatly influence sports development. Individuals with a high self-efficacy level are more likely to set tougher goals and work harder to achieve them. We aimed to investigate the relationship between sports aggression and sports mindfulness with sports self-efficacy in male athletes through the mediating role of family cohesion. Material and Methods: The statistical population of this descriptive-correlational study covered all male athletes who are members of the youth and adult male football teams in Masjed Soleyman (Iran) in 2021. The 258 athletes were selected using convenience sampling. The research tools included the Sports Self-Efficacy Questionnaire, the Buss-Perry Aggression Questionnaire, the Mindfulness Inventory for Sport, and the Family Cohesion Questionnaire. The proposed model was evaluated using path analysis and indirect correlations were tested with bootstrapping. Results: The results suggested that all direct paths to sport self-efficacy were significant except sports mindfulness (P<0.01), and indirect paths to sports self-efficacy became significant through family cohesion (P<0.01). Conclusion: The proposed model had a good fit, and was a major step toward recognizing the factors affecting sports self-efficacy in male athletes, and can help in designing programs to reduce their experienced tension and improve their sports self-efficacy.
