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    Movement Disorders Clinical Practice

    Movement Disorders Clinical Practice

    JournalISSN 2330-1619eISSN 2330-1619中科院 医学 4区

    年发文量

    研究主题

    论文(49628)

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    1Should Huntington's Disease Remains the First Genetic Consideration in Adults Presenting with Combined Chorea and Ataxia in Resource‐Limited Settings?
    Pedro Fraiman,Rodrigo Alencar e Silva, Fátima de Menezes Dantas,José Luiz Pedroso,Orlando Graziani Povoas Barsottini,Clécio de Oliveira Godeiro Junior
    2026
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    2The Phenomenology of the Golfers’ Yips, a Video‐Panel Study
    Erik van Wensen, Beorn Gerrit Nijenhuis, Esmee van Leeuwen,Roberto Erro,Christos Ganos, Rick Helmich, Hyder Jinnah, Lisette Koens, André Lee,Davide Martino,Eavan McGovern,Francesca Morgante,

    Abstract Background There is ongoing debate on the nature and the phenomenology of the golfers’ yips. Objectives To clarify the phenomenology of the golfers’ yips, based on assessment of videos by expert neurologists. Methods A panel of 13 movement disorder neurologists reviewed videos of 15 golfers (10 with and 5 without the yips). Videos showed wrist movements during putting, in three conditions: both hands, right and left hand only. The presence or absence of a movement disorder and its phenomenology was collected via a short questionnaire. Results The video panel classified the yips as a movement disorder with high overall diagnostic accuracy (0.84[95% CI: 0.71–0.92, p < 0.001]) and significant inter‐rater reliability (Gwet‐AC1 = 0.56, 95% CI: 0.46–0.67, p < 0.001). The phenomenology was predominantly classified as dystonia with significant inter‐rater reliability (Gwet‐AC1 = 0.57, 95% CI: 0.44–0.69, p < 0.001). Conclusions A panel of expert neurologists considered the golfers’ yips a neurological movement disorder, most consistent with dystonia.

    2026
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    3Restless Legs Syndrome Aggravation Associated with Berberine Use
    Kiara Cerda, Eric M. Davis,Elias Georges Karroum
    2026
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    4Nonpharmacological Interventions in Degenerative Cerebellar Ataxia: A Systematic Review
    Divyani Garg, Jacob Yomtoob,Puneet Opal,Pramod Kumar Pal

    Abstract Background A comprehensive synthesis of nonpharmacological interventions (NPI) in degenerative cerebellar ataxia will clarify their efficacy and inform clinical practice and trial design in a field with limited therapeutic options. Methods A Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA)‐compliant systematic review was conducted (PROSPERO CRD42025649802). PubMed/MEDLINE, EMBASE, Scopus, Web of Science, and Cochrane CENTRAL were searched from inception to April 16, 2025. Randomized and nonrandomized interventional studies evaluating rehabilitation, speech therapy, noninvasive neuromodulation (repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation [tDCS]), virtual reality, vibration therapy, biofeedback‐based, assistive devices, and complementary approaches were included. Methodological quality was assessed using the Joanna Briggs Institute Critical Appraisal Checklists. Given substantial clinical and methodological heterogeneity, findings were consolidated narratively. Results A total of 100 studies met inclusion criteria. Structured physical therapy, rTMS, and tDCS demonstrated statistically significant short‐term reductions in ataxia severity (measured using Scale for the Assessment and Rating of Ataxia [SARA] or International Cooperative Ataxia Rating Scale [ICARS]). Improvements were most consistent in axial domains, including gait and postural control. Limited mechanistic studies reported restoration of cerebellar inhibitory modulation, increased cerebellar–frontal connectivity, and enhanced regional perfusion following tDCS. Evidence for speech therapy, virtual reality–based rehabilitation, vibration therapy and complementary approaches was limited. Across all modalities, durability beyond the short‐term remained unclear. Conclusions NPI may confer short‐term symptomatic and functional benefits in degenerative cerebellar ataxia, particularly in axial motor domains, supported by the largest evidence for structured rehabilitation followed by neuromodulation, although heterogeneous. Future multicenter, biomarker‐informed trials are required to define optimal dosing, durability and stage‐specific therapeutic strategies.

    2026
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    5Telling the Future: Narrative Frameworks to Navigate Ethical Challenges in Prodromal Parkinson's Disease
    Jordan Larsen, Elliott Hayden,Sneha Mantri
    2026
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    立即登录,查看全部 49628 篇论文

    高被引作者

    作者引用发文
    Werner Poewe38045566
    Anthony E. Lang24391423
    Andrew Lees23201401
    Joseph Jankovic22090388
    Kaliash Bhatia21688497
    Gregor K. Wenning19439227
    Klaus Seppi19049271
    Niall Quinn18690116
    Dag Aarsland18600100
    Irene Litvan18363139

    高产作者

    作者引用发文
    Werner Poewe38045566
    Kaliash Bhatia21688497
    Anthony E. Lang24391423
    Christine Klein11397415
    Andrew Lees23201401
    Joseph Jankovic22090388
    Michael S. Okun4952347
    Bastiaan R. Bloem13464318
    Olivier Rascol14767317
    Nir Giladi9939296

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    Neurology and Therapy
    Arquivos De Neuro-psiquiatria
    MULTIPLE SCLEROSIS JOURNAL-EXPERIMENTAL TRANSLATIONAL and CLINICAL
    TREMOR and OTHER HYPERKINETIC MOVEMENTS