This chapter presents a review of key publications from 2024, focusing on two areas in which NMR has been applied extensively.
This chapter reviews studies published during the period of May 2024 to April 2025 that have applied magnetic resonance spectroscopy to investigate processes occurring in living systems. In Section 1, new hardware, acquisition methods and analytical processes that are applicable to in vivo investigations are presented. Studies in pre-clinical models and the clinical environment are surveyed in Sections 2 and 3, respectively. The review in both these two sections is subdivided into physiological categories, with each of these sub-divided according to the category of disease or the type of metabolic investigation.
This solid-state NMR report summarises the subject and results of selected articles and original papers published in 2024. In addition to the published reviews, the two major sections in this report consider various methodological developments and a broad range of applications. The presented classification of papers into different sections and subsections is intended to ease the overview of the results, as well as to evaluate the directions in which solid-state NMR techniques and applications are likely to develop in the near future. The overall survey of published papers indicates that the number of solid-state NMR applications to electrolyte materials and complex biological systems is expected to continue increasing in the coming years.
In the current chapter the progress in theoretical methodology of nuclear shielding calculation and its application, reported from the 1st of January 2024 to 31st of December 2024, is briefly reviewed. It continues the annual series of reports on the important physical phenomenon of nuclear shielding, presenting content in seven selected and partially overlapping thematic sections. It starts with an introduction, followed by reviews on nuclear shielding calculations, methodological aspects, and the application of density functional theory (DFT) for shielding prediction. The last two sections deal with calculation of nuclear shieldings in natural products and the solid state. The final part of the chapter reports on some miscellaneous applications and rare works, including the interplay between experimental NMR studies of small molecules in the gas phase and theoretical calculation of nuclear shieldings and indirect coupling constants. Some machine learning and statistical approaches are also mentioned.
This chapter provides an overview of recent advances in measuring, analyzing and applying nuclear spin relaxation via NMR to probe how molecules move in chemical systems. Approximately 100 research papers published between mid-2023 and late-2024 are summarized, grouped by phase of matter (solid, liquid, gas, mixtures, in vivo) and technique (theory and simulation; experiment - solvent-relaxation, co-solute relaxation, relaxationdispersion mapping, fast-field cycling, in vivo, etc; hardware) with the aim of highlighting notable findings, new concepts and methods, plus other information of general interest.
