КЛИНИЧЕСКИЕ АСПЕКТЫ И БИОХИМИЧЕСКИЕ МАРКЕРЫ ФОРМИРОВАНИЯ КОСТНОЙ ТКАНИ ПОСЛЕ ПЕРЕСАДКИ ПЕЧЕНИ

Biochemical markers of bone formation [osteocalcin (OC), N-terminal propeptid of type 1 procollagen (P1NP), bone isoferment of alkaline phosphatase (BALP)] were estimated in 34 recipients after liver transplantation. Three types of deviation have been demonstrated: combination elevated circulating levels OC and P1NP with normal levels BALP in recipients without clinical postoperative complication; combination lower levels OC and BALP with normal levels P1NP in recipients as a result of corticosteroid therapy prior/ following transplantation; superior levels P1NP with normal levels OC and BALP which results excessive accumulation hepatic collagen formation in recipients with postoperative clinical complication.