Petrogenetic and geochemical pecularyties of granitoids of topolninskii areal of Moutain Altai devoted in paper. Areal involve two massives: Karaminskii and Topolninskii that it wtre formed in 5 phases from gabbroid to leikogranits. The plutonic phases accompany by dike sierie of rocks. The plutonic varieties carry off to I-type granites strong contamination and reduced. The strong reduction of melts linked with contamination of carbonic rocks of country measures. Ratio of isotopes strontiam (87Sr/86Sr) point out on the mantle character of melts and contamination of crust materials. Parameters of luid regime of magmatic stage evaluted: parcial pressure of carbonic acid, water, fugacity of oxiganium, hydrochloric acid, fl uoric acid. Biotites of intratelluric phase contain high concentration of copper, gold, bismuth. Skarn, loads and gold black shale ore mineralization of gold connected with granitoids.