A new simple method for the synthesis of arylthiocyanates from aniline, pyrrole and indole derivatives has been developed. The synthesized compounds possess antimicrobial activity. Dithiocyanato derivatives of N-methylpyrrole and N-phenylpyrrole are active against fungal species of Candida albicans , Candida tropicalis , Candida krusei and Aspergillus niger . Their activity level is similar to that of fluconazole and amphotericin.