Cardiovascular diseases are the main cause of disability and mortality in developed countries. Identifying patients for primary prevention is not conducted in time today. Therefore, searching the methods that allow making a selection of patients for high-tech diagnostic methods seems to be very important. The authors conducted pathology screening of magistral arteries in an industrial organization. In total, were surveyed 991 patients of both sexes aged over 45 years (mean age — 55,6±0,16 years). As a result of screening, were identified 58 patients (5.8%) with a decrease of ankle-brachial index (ABI) (of them 42 people — 72,4% with subclinical course of disease), 7 patients (0,7%) with carotid stenosis or occlusion, and 3 patients (0,3%) with indications for coronary angiography.