Экспрессия Рецепторов К Соматостатину 1, 2, 3 И 5 Типов В Нейроэндокринных Опухолях Поджелудочной Железы

It was examined the expression of somatostatin receptors 1, 2, 3 and 5 types in 56 pancreatic neuroendocrine tumors: 48 function (45 insulinomas and 3 gastrinomas) and 18 non-function tumors. Twenty of 56 tumors were malignant (6 insulinomas, 9 non-function tumors, 3 gastrinomas). In function tumors dominated expression of receptor of 3 type (48%), and in non-function tumors type 2 (63.2%). In tumors with metastases the number of cells expressing the receptor type 2 and 3 increased, and receptor type 1 decreased.