Гетерогенность Распределения Цитотоксических Т-лимфоцитов В Строме Инвазивной Карциномы Молочной Железы: Прогностическое Значение

In the present study evaluated the distribution of leukocytes and cytotoxic T-lymphocytes in the stroma of various morphological structures of the invasive component of the breast cancer (IC NST) and association with tumor progression. Determined by immunohistochemistry CD3 +, CD45LCA + and CD8 + cells which are located near the tumor entities, as well as from those in the distance. Was determined relationship between presence of cytotoxic T-lymphocytes in the microenvironment of the discrete tumor cells, as well as in infiltrate the distance of any tumor structures and hematogenous, but not lymph node metastasis, and recurrence.