Comparative research of an ultraviolet C (UVC) action and anti-Fas monoclonal antibody on apoptosis regulation of human neutrophils at action endotoxins (LPS) was carried out. It is shown, that at action UVC and anti-Fas monoclonal antibody inhibition of LPS-dependent neutrophil apoptosis considerably decreases. Thus UVC is more effective in comparison with action anti-Fas monoclonal antibody. It is established, that UVC reduces LPS-induced neutrophil activation.