42 eyes of 21 rabbits were examined. Experimental animals were divided into 4 groups. In group 1 a subtotal vitrectomy with vancomicin 30 mcg/ml solution as irrigation solution was performed, in group 2 vitrectomy with BSS solution as irrigation solution with antibacterial photodynamic therapy (APDT), in group 3 vitrectomy with vancomicin and APDT. There was no any treatment in control group. Morphological examination was made. The best effect of anti-inflammatory therapy was reached in group 3. Quantitative evaluation of inflammatory process morphological features had decreased from 14,5 points in 1 days to 6,75 points in 14 days.