Влияние Соли Кадмия На Функциональное Состояние Крупноклеточных Ядер Гипоталамуса Белых Крыс В Зимний И Летний Периоды

The morpho-functional condition of supraoptical and paraventricular nuclei of hypothalamus peptide system of males and females of white rats in the conditions of cadmium intoxication during the most contrasting seasons of the year, winter and summer, is considered in the paper. The general mechanisms of reorganizations of hypothalamus large cell nuclei are revealed. The activity of supraoptical and paraventricular nuclei of hypothalamus of both sexes was considerably higher during the winter period in comparison with summer. Sexual differences of control animals were observed only in supraoptical nucleus and only during the winter period, thus, the functional activity in nucleus of males was higher. The chronic intoxication by chloride of cadmium has led to decrease in the functional activity of neurosecretion cells both supraoptical and paraventricular nuclei -at males in a greater degree in summer, and at females in winter.