Профилактика Нефротоксичности Аминогликозидных Антибиотиков В Интенсивной Терапии Сепсиса

A new method of prevention of aminoglycoside anibiotics nephrotoxicity in sepsis intensive treatment has been developed. It is based on the elevation of the restored glutathione level in the plasma by means of additional administration of acetylcysteine and melatonin. This leads to the decrease of nephrotoxicity, patients' lethality and their condition severity according to the APACHE II score.